Now showing items 1-3 of 3

  • Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy''): the influence of gender and genetics (CYP2D6, COMT, 5-HTT) 

    Pardo-Lozano, Ricardo; Farré, Magí; Yubero-Lahoz, Samanta; O’Mathúna, Brian; Torrens, M.; Mustata, Cristina; Pérez-Mañá, Clara; Langohr, Klaus; Cuyàs, Elisabet; Carbó, Marcel·lí; de la Torre, Rafael (2012-10-24)
    Article
    Open Access
    The synthetic psychostimulant MDMA (63,4-methylenedioxymethamphetamine, ecstasy) acts as an indirect serotonin, dopamine, and norepinephrine agonist and as a mechanism-based inhibitor of the cytochrome P-450 2D6 (CYP2D6). ...
  • Ethanol induces hydroxytyrosol formation in humans 

    Pérez-Mañá, Clara; Farré, Magí; Pujadas, Mitona; Mustata, Cristina; Menoyo, Ester; Pastor, Antoni; Langohr, Klaus; De la Torre Fornell, Rafael (2015)
    Article
    Open Access
    Previous studies in animals have shown an increase of hydroxytyrosol (OHTyr), a potent phenolic antioxidant and a minor metabolite of dopamine (also called 3,4-dihydroxyphenylethanol or DOPET), after ethanol intake. The ...
  • Non-linear formation of EtG and FAEEs after controlled administration of low to moderate doses of ethanol 

    Pérez-Mañá, Clara; Farré, Magí; Pastor, Antoni; Fonseca, Francina; Torrens, Marta; Menoyo, Ester; Pujadas, Mitona; Frias, Silvia; Langohr, Klaus; De la Torre Fornell, Rafael (2017-09-01)
    Article
    Open Access
    Aims Ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEEs) are non-oxidative metabolites of alcohol that can be detected in conventional and non-conventional biological matrices for longer periods than alcohol. The ...