Now showing items 1-20 of 65

    • 3D reconstruction and quantification of porous structures 

      Vergés Garcia, Eduard; Ayala Vallespí, M. Dolors; Grau Carrión, Sergi; Tost Pardell, Daniela (2008)
      Article
      Restricted access - publisher's policy
      In this paper, we describe the methodology that we have designed to quantify the pores distribution in bone implants and the empirical results that we have obtained with BioCAD designed scaffolds, microCT and confocal ...
    • 3D-printed calcium phosphate scaffolds for bone regeneration: impact of geometry and treatment an in vivo study 

      Lehmann, Cyril Jean Roland Louis (Universitat Politècnica de Catalunya, 2020-02-18)
      Master thesis
      Open Access
      Covenantee:   Université de Lorraine
      The combination of the direct ink writing (DIW) manufacturing technique, also named robocasting, with the use of self-setting calcium phosphate inks based on α-tricalcium phosphate opens new possibilities ...
    • A low elastic modulus Ti-Nb-Hf alloy bioactivated with an elastin-like 

      González, Marta; Salvagni, Emiliano; Rodríguez Cabello, J.C.; Rupérez de Gracia, Elisa; Gil Mur, Francisco Javier; Manero Planella, José María; Peña, Javier (2012)
      Article
      Restricted access - publisher's policy
      Covenantee:   Universidad de Valladolid
      b-type titanium alloys with low Young’s modulus are desirable to reduce stress shielding effect and enhance bone remodeling for implants used to substitute failed hard tissue. For biomaterials application, the surface ...
    • Accelerated hardening of nanotextured 3D-plotted self-setting calcium phosphate inks 

      Raymond Llorens, Santiago; Maazouz, Yassine; Montufar Jiménez, Edgar Benjamin; Perez, Roman A.; González Arcos, Borja; Konka, Joanna Magdalena; Ginebra Molins, Maria Pau (Elsevier, 2018-01-01)
      Article
      Open Access
      Direct ink writing (DIW) techniques open up new possibilities for the fabrication of patient-specific bone grafts. Self-setting calcium phosphate inks, which harden at low temperature, allow obtaining nanostructured scaffolds ...
    • Angiogenesis in bone regeneration: tailored calcium release in hybrid fibrous scaffolds 

      Castaño Linares, Óscar; Sachot, Nadège; Xuriguera Martin, Elena; Engel López, Elisabeth; Planell Estany, Josep Anton; Park, Jaegyun; Jin, Guang-Zhen; Kim, Tae-Hyun; Kim, Joong-Hyun; Kim, Hae-Won (2014-05-28)
      Article
      Restricted access - publisher's policy
      Covenantee:   Tan'guk Taehakkyo
      In bone regeneration, silicon-based calcium phosphate glasses (Bioglasses) have been widely used since the 1970s. However, they dissolve very slowly because of their high amount of Si (SiO2 > 45%). Recently, our group has ...
    • Bio-CAD analysis of porosity bioimplants 

      Vergés Garcia, Eduard; Ayala Vallespí, M. Dolors; Grau Carrión, Sergi; Tost Pardell, Daniela (2008)
      Conference report
      Restricted access - publisher's policy
      In this work we present two methods to compute the porosity from a μCT image. One is the virtual simulation of a porosimeter and the other is a sphere-based heuristic approach. Both methods obtain a graph representing the ...
    • Biofunctionalization of titanium surfaces for osseintegration process improvement 

      Sevilla Sánchez, Pablo; Godoy Gallardo, Maria; Rodríguez Rius, Daniel; Gil Mur, Francisco Javier (Institute Of Physics Publishing Ltd, 2010-06-01)
      Article
      Restricted access - publisher's policy
      This study aims to improve the osseointegration of titanium implants through surface immobilization of peptides that induce a beneficial biological response. This was carried out biofunctionalizating titanium surfaces by ...
    • Biomaterials with antimicrobial properties for bone regeneration 

      Lafferranderie Lafferranderie, Camille (Universitat Politècnica de Catalunya, 2019-02-08)
      Master thesis
      Open Access
      Covenantee:   Université de Lorraine
      The geometry, arrangement and size of the topographic elements of the surface of a biomaterial has a very important impact on bacterial adhesion. This project aims to investigate the effect of nano and microtopography of ...
    • Caracterización fisicoquímica de materiales de regeneración ósea y su aplicación para la liberación local de antibióticos 

      Sabaté Salvador, Ramon (Universitat Politècnica de Catalunya, 2015-07)
      Bachelor thesis
      Restricted access - author's decision
      El proyecto estudia la viabilidad de cargar materiales de regeneración ósea con antibiótico (doxiciclina) de manera profiláctica. Para ello se han caracterizado las propiedades fisicoquímicas de los distintos materiales ...
    • Caracterización y optimización de superfícies biomimétricas pra regeneración de Ttjido óseo 

      Paredes Méndez, Virginia Nathaly (Universitat Politècnica de Catalunya, 2012-10-26)
      Doctoral thesis
      Open Access
      Este proyecto se propone caracterizar y optimizar superficies biofuncionalizadas con diferentes secuencias peptídicas, para lograr la regeneración ósea (oseointegración) y por ende la disminución de los problemas de ...
    • Comportamiento celular en andamios fabricados por rapid prototyping para la ingeniería tisular ósea 

      Puech, Laurent (Universitat Politècnica de Catalunya, 2013-02)
      Master thesis (pre-Bologna period)
      Open Access
      La fabricación de nuevos andamios biodegradables capaces de guiar y estimular la regeneración ósea es un objetivo de gran importancia en la ingeniería de los tejidos. En este sentido, se han desarrollado innovadoras ...
    • Computed tomography and histological evaluation of xenogenic and biomimetic bone grafts in three-wall alveolar defects in minipigs 

      Raymond Llorens, Santiago; Pastorino Carraz, David; Ginebreda, Ignacio; Maazouz, Yassine; Ortiz, Mònica; Manzanares, Maria Cristina; Ginebra Molins, Maria Pau (2021-05-01)
      Article
      Open Access
      Covenantee:   Mimetis Biomaterials / Universitat Internacional de Catalunya / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental
      Objectives This study aimed to compare the performance of a xenograft (XG) and a biomimetic synthetic graft (SG) in three-wall alveolar defects in minipigs by means of 3D computerised tomography and histology. Materials ...
    • Desarrollo de andamios macroporosos. Hidroxiapatita-Gelatina para aplicaciones en ingeniería de tejidos óseos 

      De Bona Rocha, Tatiane (Universitat Politècnica de Catalunya, 2009-06)
      Master thesis
      Restricted access - author's decision
      En el presente trabajo se buscó desarrollar andamios macroporosos, basados en cementos de fosfato de calcio, para aplicaciones en ingeniería de tejidos, más específicamente para la regeneración ósea. La optimización y ...
    • Desarrollo y caracterización de materiales biodegradables para regeneración ósea 

      Navarro Toro, Melba (Universitat Politècnica de Catalunya, 2005-07-08)
      Doctoral thesis
      Open Access
      Actualmente, en el área de los biomateriales destinados a la fijación y regeneración ósea, existe un interés creciente en el desarrollo de materiales que sean reabsorbibles y a su vez, capaces de estimular la regeneración ...
    • Design of calcium phosphate scaffolds with controlled simvastatin release by plasma polymerisation 

      Canal Barnils, Cristina; Khurana, Kanupriya; Gallinetti, Sara; Bhatt, Sudhir; Pulpytel, Jerome; Arefi Khonsari, Farzaneh; Ginebra Molins, Maria Pau (Elsevier, 2016-06-01)
      Article
      Open Access
      Covenantee:   Université Pierre et Marie Curie / Universitat Autònoma de Barcelona
      Calcium Phosphates (CaPs) have excellent bone regeneration capacity, and their combination with specific drugs is of interest because it allows adding new functionalities. In CaPs, drug release is mainly driven by diffusion, ...
    • Development of 3D-printed biodegradable composite scaffolds for tissue engineering applications 

      Serra, Tiziano (Universitat Politècnica de Catalunya, 2014-04-29)
      Doctoral thesis
      Open Access
      The design of smart biodegradable scaffolds plays a crucial role in the regeneration of tissues and restoration of their functionality. Advances in material science and manufacturing and in the understanding on the effects ...
    • Development of alginate hydrogels for bone regeneration 

      Mahalia, Marion (Universitat Politècnica de Catalunya, 2021-02-17)
      Master thesis
      Open Access
      El hueso es un tejido capaz de regenerarse por sí mismo después de una lesión. Sin embargo, cuando el defecto es demasiado grande, esto es imposible, y se debe utilizar un injerto de hueso. Las limitaciones asociadas a ...
    • Directing bone marrow-derived stromal cell function with mechanics 

      Potier, Esther; Noailly, Jérôme; Ito, Keita (2010-03-22)
      Article
      Restricted access - publisher's policy
      Because bone marrow-derived stromal cells (BMSCs) are able to generate many cell types, they are envisioned as source of regenerative cells to repair numerous tissues, including bone, cartilage, and ligaments. Success ...
    • Early-stage macroporosity enhancement in calcium phosphate cements by inclusion of poly(N-vinylpyrrolidone) particles as a porogen 

      Lodoso Torrecilla, Irene; Stumpel, Floris; Jansen, John A.; van den Beucken, Jeroen J.J.P. (Elsevier, 2020-06-01)
      Article
      Open Access
      The incorporation of poly(DL-lactic-co-glycolic acid) (PLGA) particles into calcium phosphate cements (CPCs) is an effective strategy to enhance CPC macroporosity and degradation. However, bone regeneration is hindered ...
    • Electrospun gelatin/poly(epsilon-caprolactone) fibrous scaffold modified with calcium phosphate for bone tissue engineering 

      Rajzer, Izabella; Menaszek, Elzbieta; Kwiatkowski, Ryszard; Castaño Linares, Óscar; Planell Estany, Josep Anton (2014-11-01)
      Article
      Restricted access - publisher's policy
      In this study gelatin (Gel) modified with calcium phosphate nanoparticles (SG5) and polycaprolactone (PCL) were used to prepare a 3D bi-layer scaffold by collecting electrospun PCL and gelatin/SG5 fibers separately in the ...