Now showing items 1-6 of 6

  • Changes in the drug release pattern of fresh and set simvastatin-loaded brushite cement 

    Mestres Beà, Gemma; Kugiejko, Karol; Pastorino Carraz, David; Unosson, Johanna; Ohman, Caroline; Karlsson Ott, Marjam; Ginebra Molins, Maria Pau; Persson, Cecilia (2016-01-01)
    Article
    Open Access
    Covenantee:  Uppsala universitet
    Calcium phosphate cements are synthetic bone graft substitutes able to set at physiological conditions. They can be applied by minimally invasive surgery and can also be used as drug delivery systems. Consequently, the ...
  • Elastic properties and strain-to-crack-initiation of calcium phosphate bone cements: revelations of a high-resolution measurement technique 

    Ajaxon, Ingrid; Acciaioli, A.; Lionello, G.; Ginebra Molins, Maria Pau; Ohman, Caroline; Baleani, M.; Persson, Cecilia (Elsevier, 2017-10-01)
    Article
    Open Access
    Calcium phosphate cements (CPCs) should ideally have mechanical properties similar to those of the bone tissue the material is used to replace or repair. Usually, the compressive strength of the CPCs is reported and, more ...
  • Evaluation of a porosity measurement method for wet calcium phosphate cements 

    Ajaxon, Ingrid; Maazouz, Yassine; Ginebra Molins, Maria Pau; Ohman, Caroline; Persson, Cecilia (2015)
    Article
    Open Access
    Covenantee:  Uppsala universitet
    The porosity of a calcium phosphate cement is a key parameter as it affects several important properties of the cement. However, a successful, non-destructive porosity measurement method that does not include drying has ...
  • Evaluation of bone formation in calcium phosphate scaffolds with mu CT-method validation using SEM 

    Lewin, Susanne; Barba Martí, Antonio; Persson, Cecilia; Franch Serracanta, Jordi; Ginebra Molins, Maria Pau; Ohman, Caroline (2017-12-01)
    Article
    Open Access
    Covenantee:  Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animal
    There is a plethora of calcium phosphate (CaP) scaffolds used as synthetic substitutes to bone grafts. The scaffold performance is often evaluated from the quantity of bone formed within or in direct contact with the ...
  • Osteoinduction by foamed and 3D-printed calcium phosphate scaffolds: effect of nanostructure and pore architecture 

    Barba Serrahima, Albert; Díez Escudero, Anna; Maazouz, Yassine; Rappe, K.; Español Pons, Montserrat; Montufar Jiménez, Edgar Benjamin; Bonany Mariñosa, Mar; Sadowska, Joanna Maria; Guillem Martí, Jordi; Ohman, Caroline; Persson, Cecilia; Manzanares, Maria Cristina; Franch Serracanta, Jordi; Ginebra Molins, Maria Pau (2017-12-06)
    Article
    Open Access
    Covenantee:  Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animal / Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental
    Some biomaterials are osteoinductive, that is, they are able to trigger the osteogenic process by inducing the differentiation of mesenchymal stem cells to the osteogenic lineage. Although the underlying mechanism is still ...
  • Porosity prediction of calcium phosphate cements based on chemical composition 

    Ohman, Caroline; Unusson, Johanna; Carlsson, Elin; Ginebra Molins, Maria Pau; Persson, Cecilia; Engqvist, Hakan (2015-07-01)
    Article
    Open Access
    Covenantee:  Uppsala universitet
    The porosity of calcium phosphate cements has an impact on several important parameters, such as strength, resorbability and bioactivity. A model to predict the porosity for biomedical cements would hence be a useful tool. ...