Now showing items 1-3 of 3

    • A practical guide for mutational signature analysis in hematological malignancies 

      Maura, Francesco; Degasperi, Andrea; Nadeu, Ferran; Leongamornlert, Daniel; Davies, Helen; Moore, Luiza; Royo, Romina; Ziccheddu, Bachisio; Puente, Xose S.; Avet-Loiseau, Herve; Cambell, Peter J.; Nik-Zainal, Serena; Campo, Elias; Munshi, Nikhil; Bolli, Niccolò (Nature Research, 2019)
      Article
      Open Access
      Analysis of mutational signatures is becoming routine in cancer genomics, with implications for pathogenesis, classification, prognosis, and even treatment decisions. However, the field lacks a consensus on analysis and ...
    • IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms 

      Nadeu, Ferran; Mas-de-les-Valls, Rut; Navarro, Alba; Royo, Romina; Martín, Silvia; Villamor, Neus; Suárez-Cisneros, Helena; Mares, Rosó; Lu, Junyan; Enjuanes, Anna; Rivas-Delgado, Alfredo; Aymerich, Marta; Baumann, Tycho; Colomer, Dolors; Delgado, Julio; Morin, Ryan D.; Zenz, Thorsten; Puente, Xose S.; Campbell, Peter J.; Beà, Sílvia; Maura, Francesco; Campo, Elías (Springer Nature, 2020-07)
      Article
      Open Access
      Immunoglobulin (Ig) gene rearrangements and oncogenic translocations are routinely assessed during the characterization of B cell neoplasms and stratification of patients with distinct clinical and biological features, ...
    • Minimal spatial heterogeneity in chronic lymphocytic leukemia at diagnosis 

      Nadeu, Ferran; Royo, Romina; Maura, Francesco; Dawson, Kevin J; Dueso Barroso, Ana; Aymerich, Marta; Pinyol, Magda; Beà, Sílvia; López Guillermo, Armando; Delgado, Julio; Puente, Xosé S.; Campo, Elías (Springer Nature, 2020)
      Article
      Open Access