Now showing items 1-13 of 13

    • 3D silicon doped hydroxyapatite scaffolds decorated with Elastin-like Recombinamers for bone regenerative medicine 

      Vila, Mercedes; García, Ana; Girotti, Alessandra; Alonso, Matilde; Rodriguez Cabello, Jose Carlos; Gonzalez Vazquez, Arlyng; Planell Estany, Josep Anton; Engel López, Elisabeth; Buján, Julia; García Honduvilla, Natalio; Vallet Regi, Maria (2016-11-01)
      Article
      Open Access
      The current study reports on the manufacturing by rapid prototyping technique of three-dimensional (3D) scaffolds based on silicon substituted hydroxyapatite with Elastin-like Recombinamers (ELRs) functionalized surfaces. ...
    • Análisis de matrices 3D con arquitectura regular para ingeniería de tejidos 

      Marsal Boyer, Èlia (Universitat Politècnica de Catalunya, 2009-09)
      Master thesis (pre-Bologna period)
      Open Access
      Los estímulos mecánicos en las células son uno de los factores relacionados con la actividad celular. Estos estímulos mecánicos se estudian para la regeneración de tejido dañado dentro de la disciplina de ingeniería de ...
    • Bioimpresión 3D de Saffolds para medicina regenerativa 

      Ramírez García, Karoll Tatiana (Universitat Politècnica de Catalunya, 2018-10-23)
      Bachelor thesis
      Restricted access - author's decision
      Bioimpresión 3D de andamios para medicina regenerativa o Ingeniería de Tejidos. Se desarrollarán andamios tridimensionales basados en hidrogeles como el Alginato combinado con nanoparticulas de Fosfato de Calcio. Se ...
    • Comportamiento reológico de geles biodegradables para aplicacions en medicina regenerativa 

      Reyes Ortega, F.; Rodríguez, G.; Rosa Aguilar, M.; García-Sanmartín, J.; Martínez, A.; San Román, J. (Sociedad Ibérica de Biomecánica y Biomateriales (SIBB), 2012-06)
      Article
      Open Access
      Resumen Los hidrogeles (HG) poliméricos son redes macromoleculares tridimensionales constituidas por elementos básicos conectados entre sí física o químicamente e hinchados por un disolvente. Los HG poliméricos tienen ...
    • Development and angiogenic potential of cell-derived microtissues using microcarrier-template 

      Rubi Sans, Gerard; Cano Garcia, Irene; Pérez Amodio, Soledad Graciela; Blanco, Bárbara; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth (2021-02-25)
      Article
      Open Access
      Tissue engineering and regenerative medicine approaches use biomaterials in combination with cells to regenerate lost functions of tissues and organs to prevent organ transplantation. However, most of the current strategies ...
    • Development of 3D-printed biodegradable composite scaffolds for tissue engineering applications 

      Serra, Tiziano (Universitat Politècnica de Catalunya, 2014-04-29)
      Doctoral thesis
      Open Access
      The design of smart biodegradable scaffolds plays a crucial role in the regeneration of tissues and restoration of their functionality. Advances in material science and manufacturing and in the understanding on the effects ...
    • Dynamic behavior of type IV collagen at cell-biomaterial interface 

      Coelho, Nuno Miranda (Universitat Politècnica de Catalunya, 2012-05-25)
      Doctoral thesis
      Open Access
      The initial molecular events that take place at biomaterials interface mimic to a certain extent the natural interaction of cells with the extracellular matrix (ECM). In this thesis we describe the fate of adsorbed type ...
    • Effect of structure, topography and chemistry on fibroblast adhesion and morphology 

      Mateos Timoneda, Miguel Ángel; Castaño Linares, Óscar; Planell Estany, Josep Anton; Engel López, Elisabeth (2014-07)
      Article
      Restricted access - publisher's policy
      Surface biofunctionalisation of many biodegradable polymers is one of the used strategies to improve the biological activity of such materials. In this work, the introduction of collagen type I over the surface of a ...
    • Engineering membrane scaffolds with both physical and biomolecular signaling. 

      Tejeda-Montse, Esther; Smith, Katherine H.; Poch, Marta; López Bosque, Maria Jesús; Martín, Laura; Alonso, Matilde; Engel López, Elisabeth; Mata, Álvaro (2011-09-07)
      Article
      Restricted access - publisher's policy
      We report on the combination of a top-down and bottom-up approach to develop thin bioactive membrane scaffolds based on functional elastin-like polymers (ELPs). Our strategy combines ELP cross-linking and assembly, and a ...
    • Extracellular calcium and CaSR drive osteoinduction in mesenchymal stromal cells 

      Gonzalez Vazquez, Arlyng; Planell Estany, Josep Anton; Engel López, Elisabeth (2014-06-01)
      Article
      Restricted access - publisher's policy
      Bone is the main store of calcium and progenitor cells in the body. During the resorption process, the local calcium concentration reaches 8-40 mM, and the surrounding cells are exposed to these fluctuations in calcium. ...
    • Lignin-based nanoparticles as both structural and active elements in self-assembling and self-healing multifunctional hydrogels for chronic wound management 

      Morena Gatius, Ángela Gala; Pérez Rafael, Silvia; Tzanov, Tzanko (Multidisciplinary Digital Publishing Institute (MDPI), 2022-11-30)
      Article
      Open Access
      Efficient wound healing is feasible when the dressing materials simultaneously target multiple factors causing wound chronicity, such as deleterious proteolytic and oxidative enzymes and bacterial infection. Herein, entirely ...
    • Microsphere incorporation as a strategy to tune the biological performance of bioinks 

      Bonany Mariñosa, Mar; Mazo Bárbara, Laura del; Español Pons, Montserrat; Ginebra Molins, Maria Pau (SAGE publishing, 2022-01-01)
      Article
      Open Access
      Covenantee:   Centre de Recerca en Enginyeria Biomedica (CREB) / Institut de Bioenginyeria de Catalunya
      Although alginate is widely used as a matrix in the formulation of cell-laden inks, this polymer often requires laborious processing strategies due to its lack of cell adhesion moieties. The main objective of the present ...
    • Poly(butylene succinate) matrices obtained by thermally-induced phase separation: Pore shape and orientation affect drug release 

      Zeinali, Reza; Franco García, María Lourdes; Valle Mendoza, Luis Javier del; Puiggalí Allepuz, Jordi (Elsevier, 2022-06-14)
      Article
      Open Access
      Poly(butylene succinate) (PBS) scaffolds with 3D microporous interconnected architecture and crystallized PBS substructures have been prepared by thermally-induced phase separation (TIPS). Curcumin (CUR) and piperine (PIP) ...