Browsing by Author "Martin-Fernandez, Laura"
Next generation sequencing to dissect the genetic architecture of KNG1 and F11 loci using factor XI levels as an intermediate phenotype of thrombosis Martin-Fernandez, Laura; Gavidia Bovadilla, Giovana Elizabeth; Corrales, Irene; Brunel, Helena; Ramirez, Lorena; Lopez Esteban, Sonia; Carlos Souto, Juan; Vidal, Francisco; Soria, José Manuel (2017-04-26)
Open AccessVenous thromboembolism is a complex disease with a high heritability. There are significant associations among Factor XI (FXI) levels and SNPs in the KNG1 and F11 loci. Our aim was to identify the genetic variation of KNG1 ...
The Central role of KNG1 gene as a genetic determinant of coagulation pathway-related traits: Exploring metaphenotypes Brunel, Helena; Massanet, Raimon; Martinez Perez, Angel; Ziyatdinov, Andrey; Martin-Fernandez, Laura; Souto, Juan Carlos; Perera Lluna, Alexandre; Soria, José Manuel (2016-12-22)
Open AccessTraditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same ...