Now showing items 1-6 of 6

    • Asymmetric sulfoxidation by engineering the heme pocket of a dye-decolorizing peroxidase 

      Linde, Dolores; Cañellas, Marina; Coscolín, Cristina; Davó-Siguero, Irene; Romero, Antonio; Lucas, Fátima; Ruiz-Dueñas, Francisco J.; Guallar, Víctor; Martínez, Ángel T. (Royal Society of Chemistry, 2016-05-23)
      Article
      Open Access
      The so-called dye-decolorizing peroxidases (DyPs) constitute a new family of proteins exhibiting remarkable stability. With the aim of providing them new catalytic activities of biotechnological interest, the heme pocket ...
    • Biografting of ferulic acid onto lignocellulosic fibers by the use of laccases 

      Rencoret, Jorge; Aracri, Elisabetta; Gutíerrez, Ana; del Rio Andrade, José Carlos; Torres López, Antonio Luis; Vidal Lluciá, Teresa; Martínez, Ángel T. (2014)
      Conference lecture
      Restricted access - publisher's policy
      Laccases can functionalize paper pulps with phenolic compounds but little is known about the formed linkages. Treatment of a high-kappa sisal pulp with Trametes villosa laccase and ferulic acid resulted in strong increases ...
    • Molecular determinants for selective C 25-hydroxylation of vitamins D 2 and D 3 by fungal peroxygenases 

      Lucas, Fátima; Babot, Esteban D.; Cañellas, Marina; del Río, José C.; Kalum, Lisbeth; Ullrich, René; Hofrichter, Martin; Guallar, Víctor; Martínez, Ángel T.; Gutiérrez, Ana (Royal Society of Chemistry, 2015-08-07)
      Article
      Open Access
      Hydroxylation of vitamin D by Agrocybe aegerita and Coprinopsis cinerea peroxygenases was investigated in a combined experimental and computational study. 25-Monohydroxylated vitamin D3 (cholecalciferol) and D2 (ergocalciferol), ...
    • Rational Enzyme Engineering Through Biophysical and Biochemical Modeling 

      Acebes, Sandra; Fernández-Fueyo, Elena; Monza, Emanuele; Lucas, Fatima; Almendral, David; Ruiz-Dueñas, Fracisco J.; Lund, Henrik; Martínez, Ángel T.; Guallar, Víctor (ACS Publications, 2016-02-03)
      Article
      Open Access
      Due to its importance in the pharmaceutical industry, ligand dynamic simulations have experienced a great expansion. Using all-atom models and cutting edge hardware, one can perform non-biased ligand migration, active site ...
    • Steroid hydroxylation by basidiomycete peroxygenases: A combined experimental and computational study, Applied and environmental microbiology 

      Babot, Esteban D.; del Río, José C.; Cañellas, Marina; Sancho, Ferran; Lucas, Fatima; Guallar, Víctor; Kalum, Lisbeth; Lund, Henrik; Gröbe, Glenn; Scheibner, Katrin; Ullrich, René; Hofrichter, Martin; Martínez, Ángel T.; Gutiérrez, Ana (ASM Journals, 2015-04-10)
      Article
      Open Access
      The goal of this study is the selective oxyfunctionalization of steroids under mild and environmentally friendly conditions using fungal enzymes. With this purpose, peroxygenases from three basidiomycete species were tested ...
    • Structural insights on laccase biografting of ferulic acid onto lignocellulosic fibers 

      Rencoret, Jorge; Aracri, Elisabetta; Gutíerrez, Ana; del Río, José C.; Torres López, Antonio Luis; Vidal Lluciá, Teresa; Martínez, Ángel T. (2014-05-15)
      Article
      Restricted access - publisher's policy
      Treatment of high-kappa sisal pulp with Trametes villosa laccase and ferulic acid resulted in strong increases of kappa-number and acid-group content due to biografting of this phenolic acid, as shown by pyrolysis in the ...