Exploració per tema "Leukemia"
Ara es mostren els items 1-7 de 7
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Automatic generation of artificial images of leukocytes and leukemic cells using Generative Adversarial Networks (SyntheticCellGAN)
(2023)
Article
Accés obertBackground and objectives: Visual analysis of cell morphology has an important role in the diagnosis of hematological diseases. Morphological cell recognition is a challenge that requires experience and in-depth review by ... -
ChiPPI: a novel method for mapping chimeric protein–protein interactions uncovers selection principles of protein fusion events in cancer
(Oxford University Press, 2017-05-26)
Article
Accés obertFusion proteins, comprising peptides deriving from the translation of two parental genes, are produced in cancer by chromosomal aberrations. The expressed fusion protein incorporates domains of both parental proteins. Using ... -
Chromatin network markers of leukemia
(Oxford University Press, 2020-07)
Article
Accés obertMotivation The structure of chromatin impacts gene expression. Its alteration has been shown to coincide with the occurrence of cancer. A key challenge is in understanding the role of chromatin structure (CS) in cellular ... -
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia
(Nature Research, 2022)
Article
Accés obertRichter transformation (RT) is a paradigmatic evolution of chronic lymphocytic leukemia (CLL) into a very aggressive large B cell lymphoma conferring a dismal prognosis. The mechanisms driving RT remain largely unknown. ... -
Network community cluster-based analysis for the identification of potential leukemia drug targets
(Springer, 2019)
Comunicació de congrés
Accés obertLeukemia is a hematologic cancer which develops in blood tissue and causes rapid generation of immature and abnormal-shaped white blood cells. It is one of the most prominent causes of death in both men and women for which ... -
Optimizing morphology through blood cell image analysis
(Wiley, 2018-05-09)
Article
Accés obertIntroduction Morphological review of the peripheral blood smear is still a crucial diagnostic aid as it provides relevant information related to the diagnosis and is important for selection of additional techniques. ... -
Reconocimiento automático de células malignas en sangre periférica a partir de imágenes digitales y utilizando redes neuronales convolucionales
(Universitat Politècnica de Catalunya, 2018-06-28)
Treball Final de Grau
Accés obertExiste una gran variedad de patologías que afectan a los glóbulos blancos, desde enfermedades benignas a patologías graves. Las leucemias son patologías que se originan por proliferaciones incontroladas de los precursores ...