Browsing by Author "Krieg, Michael"
Now showing items 1-8 of 8
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Atomic force microscopy-based mechanobiology
(Nature, 2018-11-01)
Article
Open AccessMechanobiology emerges at the crossroads of medicine, biology, biophysics and engineering and describes how the responses of proteins, cells, tissues and organs to mechanical cues contribute to development, differentiation, ... -
Automated dual olfactory device for studying head/tail chemosensation in Caenorhabditis elegans
(American Institute of Physics (AIP), 2024-06-01)
Article
Open AccessThe correct interpretation of threat and reward is important for animal survival. Often, the decisions underlying these behavioral programs are mediated by volatile compounds in the animal's environment, which they detect ... -
Direct force measurements of subcellular mechanics in confinement using optical tweezers
(2021-08-31)
Article
Open AccessDuring the development of a multicellular organism, a single fertilized cell divides and gives rise to multiple tissues with diverse functions. Tissue morphogenesis goes in hand with molecular and structural changes at the ... -
Neural engineering with photons as synaptic transmitters
(Nature methods, 2023-04-06)
Article
Open AccessNeuronal computation is achieved through connections of individual neurons into a larger network. To expand the repertoire of endogenous cellular communication, we developed a synthetic, photon-assisted synaptic transmission ... -
Neuronal stretch reception – making sense of the mechanosense
(Elsevier, 2019-05-01)
Article
Open AccessThe sensation of mechanical force underlies many of our daily activities. As the sense of touch determines the quality of life, the subconscious sense of proprioception and visceral mechanosensation is indispensible for ... -
Rationally designed azobenzene photoswitches for efficient two-photon neuronal excitation
(Nature, 2019-02-22)
Article
Open AccessManipulation of neuronal activity using two-photon excitation of azobenzene photoswitches with near-infrared light has been recently demonstrated, but their practical use in neuronal tissue to photostimulate individual ... -
The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior
(ACS, 2020-10-16)
Article
Open AccessSingle cells continuously experience and react to mechanical challenges in three-dimensional tissues. Spatial constraints in dense tissues, physical activity, and injury all impose changes in cell shape. How cells can ... -
Understanding neural circuit function through synaptic engineering
(Nature reviews neuroscience, 2024-01-03)
Article
Open AccessSynapses are a key component of neural circuits, facilitating rapid and specific signalling between neurons. Synaptic engineering — the synthetic insertion of new synaptic connections into in vivo neural circuits — is an ...
