Now showing items 1-18 of 18

    • 3D printing with star-shaped strands: a new approach to enhance in vivo bone regeneration 

      Raymond Llorens, Santiago; Lehmann, Cyril; Thorel, Emilie; Benítez Iglesias, Raúl; Riveiro Rodríguez, Antonio; Pou Saracho, Juan María; Manzanares Céspedes, Maria Cristina; Franch Serracanta, Jordi; Canal Barnils, Cristina; Ginebra Molins, Maria Pau (Elsevier, 2022-06-01)
      Article
      Open Access
      Covenantee:   Mimetis Biomaterials / Institut de Recerca Sant Joan de Déu / Universidade de Vigo / Universitat de Barcelona / Universitat Autònoma de Barcelona / Institut de Bioenginyeria de Catalunya
      Concave surfaces have shown to promote bone regeneration in vivo. However, bone scaffolds obtained by direct ink writing, one of the most promising approaches for the fabrication of personalized bone grafts, consist mostly ...
    • Ceramic-hydrogel composite as carrier for cold-plasma reactive-species: Safety and osteogenic capacity in vivo 

      Solé Martí, Xavier; Labay, Cédric Pierre; Raymond Llorens, Yago; Franch, Jordi; Benítez Iglesias, Raúl; Ginebra Molins, Maria Pau; Canal Barnils, Cristina (Wiley (John Wiley & Sons), 2022-01-01)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Mimetis Biomaterials / Universitat Autònoma de Barcelona / Institut de Bioenginyeria de Catalunya
      Plasma-treated hydrogels have been put forward as a potential selective osteosarcoma therapy through the release of reactive species to the diseased site. To allow their translation to the clinics, it is crucial to show ...
    • Citric acid in the passivation of titanium dental implants: corrosion resistance and bactericide behavior 

      Verdeguer, Pablo; Gil Mur, Javier; Punset Fuste, Miquel; Manero Planella, José María; Nart, José; Vilarrasa Sánchez, Javier; Rupérez de Gracia, Elisa (Multidisciplinary Digital Publishing Institute (MDPI), 2022-01-12)
      Article
      Open Access
      Covenantee:   Universitat Internacional de Catalunya / Institut de Recerca Sant Joan de Déu
      The passivation of titanium dental implants is performed in order to clean the surface and obtain a thin layer of protective oxide (TiO2) on the surface of the material in order to improve its behavior against corrosion ...
    • Cold plasma and inhibition of STAT3 selectively target tumorigenicity in osteosarcoma 

      Tornin Cavielles, Juan; Mateu Sanz, Miguel; Rey, Veronica; Murillo, Dzohara; Huergo García, Carmen; Gallego, Borja; Rodríguez, Aida; Rodríguez, René; Canal Barnils, Cristina (2023-06-01)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Hospital Universitario Central de Asturias / Instituto Universitario de Oncología del Principado de Asturias / CIBERONC. Centro de Investigación Biomédica en Red. Cáncer
      Osteosarcoma (OS) is a malignant type of bone cancer that arises in periods of increased bone formation. Curative strategies for these types of tumors have remained essentially unchanged for decades and the overall survival ...
    • Combining 2D organic and 1D inorganic nanoblocks to develop free-standing hybrid nanomembranes for conformable biosensors 

      García Torres, José Manuel; Sylla, Dioulde Huguette; Lanzalaco, Sonia; Ginebra Molins, Maria Pau; Alemán Llansó, Carlos (2022-03-02)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Institut de Recerca en Energia de Catalunya / Institut de Bioenginyeria de Catalunya
      We report a simple approach to fabricate free-standing perforated 2D nanomembranes hosting well-ordered 1D metallic nanostructures to obtain hybrid materials with nanostructured surfaces for fexible electronics. Nanomembranes ...
    • Comparison of the antibacterial effect of silver nanoparticles and a multifunctional antimicrobial peptide on titanium surface 

      Moreno Duarte, Daniel; Buxadera Palomero, Judit; Ginebra Molins, Maria Pau; Manero Planella, José María; Martín Gómez, Helena; Mas Moruno, Carlos; Rodríguez Rius, Daniel (Multidisciplinary Digital Publishing Institute (MDPI), 2023-06-04)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Institut de Bioenginyeria de Catalunya
      Titanium implantation success may be compromised by Staphylococcus aureus surface colonization and posterior infection. To avoid this issue, different strategies have been investigated to promote an antibacterial character ...
    • Does non-thermal plasma modify biopolymers in solution? A chemical and mechanistic study for alginate 

      Tampieri, Francesco; Espona Noguera, Albert; Labay, Cédric Pierre; Ginebra Molins, Maria Pau; Yusupov, Maksudbek; Bogaerts, Annemie; Canal Barnils, Cristina (Royal Society of Chemistry (RSC), 2023-01-01)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Institut de Bioenginyeria de Catalunya / New Uzbekistan University / National Research University, Uzbekistan / Universiteit Antwerpen
      In the last decades, non-thermal plasma has been extensively investigated as a relevant tool for various biomedical applications, ranging from tissue decontamination to regeneration and from skin treatment to tumor therapies. ...
    • Functionalization of 3D printed polymeric bioresorbable stents with a dual cell-adhesive peptidic platform combining RGDS and YIGSR sequences 

      Chausse Calbet, Victor; Mas Moruno, Carlos; Martín Gómez, Helena; Pino Curto, Marc; Díaz Ricart, Maribel; Escolar Albaladejo, Ginés; Ginebra Molins, Maria Pau; Pegueroles Neyra, Marta (Royal Society of Chemistry (RSC), 2023-05-08)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Hospital Clínic i Provincial de Barcelona / Institut de Bioenginyeria de Catalunya
      Biomimetic surface modification with cell-adhesive peptides is a promising approach to improve endothelialization of current bioresorbable stents (BRS). Among them, RGDS and YIGSR sequences have been reported to mediate ...
    • Hydrothermal processing of 3D-printed calcium phosphate scaffolds enhances bone formation in vivo: a comparison with biomimetic treatment 

      Raymond Llorens, Santiago; Bonany Mariñosa, Mar; Lehmann, Cyril; Thorel, Emilie; Benítez Iglesias, Raúl; Franch Serracanta, Jordi; Canal Barnils, Cristina; Ginebra Molins, Maria Pau (Elsevier, 2021-11-01)
      Article
      Open Access
      Covenantee:   Mimetis Biomaterials / Institut de Recerca Sant Joan de Déu / Universitat Autònoma de Barcelona / Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística / Institut de Bioenginyeria de Catalunya
      Hydrothermal (H) processes accelerate the hydrolysis reaction of a-tricalcium phosphate (a-TCP) compared to the long-established biomimetic (B) treatments. They are of special interest for patient-specific 3D-printed bone ...
    • In-situ laser directed energy deposition of biomedical ti-nb and ti-zr-nb alloys from elemental powders 

      Arias González, Felipe; Rodríguez Contreras, Alejandra María; Punset Fuste, Miquel; Manero Planella, José María; Barro Guizán, Óscar; Fernández Arias, M.; Lusquiños Rodriguez, Fernando; Gil Mur, Javier; Pou, Juan (Multidisciplinary Digital Publishing Institute (MDPI), 2021-08-01)
      Article
      Open Access
      Covenantee:   Universitat Internacional de Catalunya / Institut de Recerca Sant Joan de Déu / Universidade de Vigo
      In order to achieve the required properties of titanium implants, more resources and research are needed to turn into reality the dream of developing the perfect implant material. The objective of this study was to evaluate ...
    • Laser-deposited beta type Ti-42Nb alloy with anisotropic mechanical properties for pioneering biomedical implants with a very low elastic modulus 

      Arias González, Felipe; Rodríguez Contreras, Alejandra María; Punset Fuste, Miquel; Manero Planella, José María; Barro Guizán, Óscar; Fernández Arias, M.; Lusquiños Rodriguez, Fernando; Gil, Javier; Pou, Juan (Multidisciplinary Digital Publishing Institute (MDPI), 2022-10-01)
      Article
      Open Access
      Covenantee:   Universidade de Vigo / Institut de Recerca Sant Joan de Déu / Instituto de Investigación Sanitaria Galicia Sur / Universitat Internacional de Catalunya. Facultat d'Odontologia
      Present commercial titanium alloy implants have an elastic modulus higher than 100 GPa, whereas that of the cortical bone is much smaller (17–28 GPa). This elastic modulus mismatch produces a stress shielding effect and ...
    • On-growth and in-growth osseointegration enhancement in PM porous Ti-scaffolds by two different bioactivation strategies: alkali thermochemical treatment and RGD peptide coating 

      Steffaine Rappe, Katrin; Ortiz Hernández, Mónica; Punset Fuste, Miquel; Molmeneu Trias, Meritxell; Barba Serrahima, Albert; Mas Moruno, Carlos; Guillem Martí, Jordi; Caparrós, Cristina; Rupérez de Gracia, Elisa; Calero, José; Manzanares, Maria Cristina; Gil Mur, Javier; Franch, Jordi (2022-02-01)
      Article
      Open Access
      Covenantee:   Universitat Autònoma de Barcelona / Institut de Recerca Sant Joan de Déu / AMES / Universitat de Barcelona / Universitat Internacional de Catalunya
      A lack of primary stability and osteointegration in metallic implants may result in implant loosening and failure. Adding porosity to metallic implants reduces the stress shielding effect and improves implant performance, ...
    • Osteoclast-mediated acidic hydrolysis of thermally gelled curdlan component of the bone scaffolds: Is it possible? 

      Przekora, Agata; Penolazzi, Maria Letizia; Kalisz, Grzegorz; Kazimierczak, Paulina; Canal Barnils, Cristina; Wojcik, Michal; Piva, Roberta; Sroka Bartnicka, Anna (2022-11-01)
      Article
      Open Access
      Covenantee:   Uniwersytet Medyczny w Lublinie / Università degli Studi di Ferrara / Institut de Recerca Sant Joan de Déu
      Many biomaterials for bone regeneration have recently been produced using thermally gelled curdlan (1,3-ß-d-glucan) as a binder for bioceramics. As the human organism does not produce enzymes having the ability to degrade ...
    • Oxidation of lactate to pyruvate mediates the cytotoxic potential of physical plasma-treated saline solutions in ovarian cancer 

      Bucci, Cristina; Tampieri, Francesco; Mateu Sanz, Miguel; Laurita, Romolo; Colombo, Vittorio; Canal Barnils, Cristina (John Wiley & sons, 2023-10-02)
      Article
      Open Access
      Covenantee:   Università di Bologna / Institut de Recerca Sant Joan de Déu
      Epithelial ovarian cancer (EOC) is the most common type of gynecological tumor, presenting poor prognosis at diagnosis and with recurrences being frequently observed. Reactive species generated by physical plasma and ...
    • Solvent-cast direct-writing and electrospinning as a dual fabrication strategy for drug-eluting polymeric bioresorbable stents 

      Chausse Calbet, Victor; Casanova Batlle, Enric; Canal Barnils, Cristina; Ginebra Molins, Maria Pau; Ciurana Gay, Joaquim; Pegueroles Neyra, Marta (Elsevier, 2023-06-05)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Universitat de Girona / Institut de Bioenginyeria de Catalunya
      Bioresorbable stents (BRS) are conceived to retain sufficient radial strength after implantation while releasing an antiproliferative drug in order to prevent vessel restenosis until complete resorption. Ongoing research ...
    • Surface competition between osteoblasts and bacteria on silver-doped bioactive titanium implant 

      Piñera Avellaneda, David; Buxadera Palomero, Judit; Ginebra Molins, Maria Pau; Calero, José Antonio; Manero Planella, José María; Rupérez de Gracia, Elisa (Elsevier, 2023-01-24)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Institut de Bioenginyeria de Catalunya / AMES
      The rapid integration in the bone tissue and the prevention of bacterial infection are key for the success of the implant. In this regard, a silver (Ag)-doped thermochemical treatment that generate an Ag-doped calcium ...
    • Titanium Boston keratoprosthesis with corneal cell adhesive and bactericidal dual coating 

      Gómez González, Silvia; Guillem Martí, Jordi; Martín Gómez, Helena; Mas Moruno, Carlos; Ginebra Molins, Maria Pau; Gil Mur, Francisco Javier; Barraquer Compte, Rafael Ignasi; Manero Planella, José María (Elsevier, 2023-11-01)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Institut de Bioenginyeria de Catalunya / Universitat Internacional de Catalunya / Centre d'Oftalmologia Barraquer
      The Boston keratoprosthesis (BKPro) is a medical device used to restore vision in complicated cases of corneal blindness. This device is composed by a front plate of polymethylmethacrylate (PMMA) and a backplate usually ...
    • Toughening 3D printed biomimetic hydroxyapatite scaffolds: polycaprolactone-based self-hardening inks 

      Mazo Barbara, Laura del; Johansson, Linh Ha Huong Lovisa; Tampieri, Francesco; Ginebra Molins, Maria Pau (Elsevier, 2024-02)
      Article
      Open Access
      Covenantee:   Institut de Recerca Sant Joan de Déu / Mimetis Biomaterials / Centro de Investigación Biomédica en Red. Bioingeniería, Biomateriales y Nanomedicina / Institut de Bioenginyeria de Catalunya
      The application of 3D printing to calcium phosphates has opened unprecedented possibilities for the fabrication of personalized bone grafts. However, their biocompatibility and bioactivity are counterbalanced by their high ...