Browsing by Subject "Genomics"
Now showing items 1-20 of 111
-
A FM-index transformation to enable large k-steps
(Barcelona Supercomputing Center, 2019-05-07)
Conference report
Open Access -
A hardware/software co-design of K-mer counting using a CAPI-enabled FPGA
(Institute of Electrical and Electronics Engineers (IEEE), 2020)
Conference report
Open AccessAdvances in Next Generation Sequencing (NGS) technologies have caused the proliferation of genomic applications to detect DNA mutations and guide personalized medicine. These applications have an enormous computational ... -
A model of large-scale proteome evolution
(2002-03)
Article
Open AccessThe next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent ... -
A multilayer network approach to elucidate severity in Congenital Myasthenic Syndromes
(Barcelona Supercomputing Center, 2019-05-07)
Conference report
Open Access -
A novel MMR pathway in prokaryotes
(Barcelona Supercomputing Center, 2019)
Other
Open Access -
A user guide for the online exploration and visualization of PCAWG data
(Springer Nature, 2020)
Article
Open AccessThe Pan-Cancer Analysis of Whole Genomes (PCAWG) project generated a vast amount of whole-genome cancer sequencing resource data. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which ... -
Accelerating edit-distance sequence alignment on GPU using the wavefront algorithm
(Institute of Electrical and Electronics Engineers (IEEE), 2022-06-10)
Article
Open AccessSequence alignment remains a fundamental problem with practical applications ranging from pattern recognition to computational biology. Traditional algorithms based on dynamic programming are hard to parallelize, require ... -
Accelerating K-mer Frequency Counting with GPU and Non-Volatile Memory
(IEEE, 2018-02-15)
Conference lecture
Open AccessThe emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its ... -
Accelerating K-mer Frequency Counting with GPU and Non-Volatile Memory
(2018)
Conference report
Open AccessThe emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its ... -
Accelerating pairwise sequence alignment on GPUs using the Wavefront Algorithm
(Universitat Politècnica de Catalunya, 2022-10-19)
Master thesis
Open AccessAdvances in genomics and sequencing technologies demand faster and more scalable analysis methods that can process longer sequences with higher accuracy. However, classical pairwise alignment methods, based on dynamic ... -
Acinetobacter type VI secretion system comprises a non-canonical membrane complex
(Public Library of Science, 2023-09)
Article
Open AccessA. baumannii can rapidly acquire new resistance mechanisms and persist on abiotic surface, enabling the colonization of asymptomatic human host. In Acinetobacter the type VI secretion system (T6SS) is involved in twitching, ... -
Adding security and privacy to genomic information representation
(IOS Press, 2019)
Conference lecture
Open AccessProvision of security and privacy to genomic data is a key issue in current genomic information representation. Existing formats do not give a solution to these issues (or they provide a partial one), so new solutions are ... -
Adding security and privacy to genomic information representation
(2019)
Article
Open AccessProvision of security and privacy to genomic data is a key issue in current genomic information representation. Existing formats do not give a solution to these issues (or they provide a partial one), so new solutions are ... -
An FPGA accelerator of the wavefront algorithm for genomics pairwise alignment
(Institute of Electrical and Electronics Engineers (IEEE), 2021)
Conference report
Open AccessIn the last years, advances in next-generation sequencing technologies have enabled the proliferation of genomic applications that guide personalized medicine. These applications have an enormous computational cost due to ... -
Analysis and improvement of security and privacy techniques for genomic information
(Universitat Politècnica de Catalunya, 2021-10-28)
Master thesis
Open AccessThe purpose of this thesis is to review the current literature of privacy preserving techniques for genomic information on the last years. Based on the analysis, we propose a long-term classification system for the reviewed ... -
Analysis of transposon dynamics in Prunus species using a pangenome approach
(Universitat Politècnica de Catalunya, 2021-09-02)
Bachelor thesis
Open Access
Covenantee: Centre for Research in Agricultural GenomicsTransposable elements (TEs) are repetitive DNA sequences found in all prokaryotic and eukaryotic organisms. They are able to move from one genome location to another and replicate in the genome, producing mutations and ... -
AnchorWave: Sensitive alignment of genomes with high sequence diversity, extensive structural polymorphism, and whole-genome duplication
(2022-01-04)
Article
Open AccessMillions of species are currently being sequenced, and their genomes are being compared. Many of them have more complex genomes than model systems and raise novel challenges for genome alignment. Widely used local alignment ... -
Assessment of kinship detection using RNA-seq data
(2019-12-02)
Article
Open AccessAnalysis of RNA sequencing (RNA-seq) data from related individuals is widely used in clinical and molecular genetics studies. Prediction of kinship from RNA-seq data would be useful for confirming the expected relationships ... -
Big data analytics for obesity prediction
(Universitat Politècnica de Catalunya, 2018-04-26)
Master thesis
Open Access
Covenantee: Fundació EurecatFeature selection is an important technique to find the most relevant features. Apache Spark is a big data processing framework but unable to cope with approx. 0.74 million features in our Obesity dataset. However, we ... -
BIGNASim: a NoSQL database structure and analysis portal for nucleic acids simulation data
(2016-01-04)
Article
Open AccessMolecular dynamics simulation (MD) is, just behind genomics, the bioinformatics tool that generates the largest amounts of data, and that is using the largest amount of CPU time in supercomputing centres. MD trajectories ...