Browsing by Subject "Genetics"
Now showing items 1-20 of 60
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3D lineage-specific genome architecture links regulatory elements and non-coding disease variants to target gene promoters
(Barcelona Supercomputing Center, 2018)
Conference report
Open Access -
A body mass index-based mathematical model on not frequently collected data: the case of Chile
(Universitat Politècnica de Catalunya / Universitat de Barcelona, 2021-01)
Master thesis
Restricted access - confidentiality agreement
Covenantee: Universidad de Santiago de ChileThe nutritional status is generally measured by body mass index (BMI) being obese, one of the most important non-communicable diseases, a risk factor whose estimation is especially relevant for the development of future ... -
A Compositional Approach to Allele Sharing Analysis
(Springer, 2016)
Part of book or chapter of book
Restricted access - publisher's policyRelatedness is of great interest in population-based genetic association studies. These studies search for genetic factors related to disease. Many statistical methods used in population-based genetic association studies ... -
A genetic association study of colon cancer
(Universitat Politècnica de Catalunya, 2014-07)
Bachelor thesis
Open AccessThe project of this bachelor degree concerns the statistical analysis of a genetic database provided by Professor Victor Moreno, epidemiologist of the Hospital de Bellvitge in Barcelona. The goal is to investigate associations ... -
A genome-wide study of Hardy–Weinberg equilibrium with next generation sequence data
(2017-04-03)
Article
Open AccessStatistical tests for Hardy–Weinberg equilibrium have been an important tool for detecting genotyping errors in the past, and remain important in the quality control of next generation sequence data. In this paper, we ... -
A log-ratio biplot approach for exploring genetic relatedness based on identity by state
(2019-04-24)
Article
Open AccessThe detection of cryptic relatedness in large population-based cohorts is of great importance in genome research. The usual approach for detecting closely related individuals is to plot allele sharing statistics, based on ... -
A Mathematical model of the spread of two viral sub-types on a Plant Leaf (Numerical Simulation)
(Universitat Politècnica de Catalunya, 2015-06)
Master thesis
Restricted access - author's decisionWhilst in humans free virus particles and host cells are assumed to be homogenously mixed, in plants, the spatial component is a key factor. The natural proliferation of the virus through a plant is known to happen from a ... -
Algebraic methods in phylogenetics
(2018-12-19)
Article
Open AccessTo those outside the field, and even to some focused on empirical applications, phylogenetics may appear to have little to do with algebra. Probability and statistics are clearly important ingredients, as modeling and ... -
Algorismes genètics aplicats a ciències de la vida
(Universitat Politècnica de Catalunya, 2010-01-27)
Master thesis (pre-Bologna period)
Open Access -
Ampliación de un modelo de Markov para evaluar estrategias de prevención de enfermedades relacionadas con el VPH
(Universitat Politècnica de Catalunya / Universitat de Barcelona, 2020-01)
Master thesis
Restricted access - author's decision
Covenantee: Institut Català d'OncologiaActualmente, el Virus del Papiloma Humano (VPH) es la infección de transmisión sexual más común que existe. La persistencia de este puede provocar distintos cánceres, siendo el más común el cáncer cervical. El objetivo de ... -
Analysis of clinical diagnostics in human genetics with semantic similarity searches in ontologies
(Universitat Politècnica de Catalunya, 2022-07-05)
Master thesis
Open AccessThis thesis is focused on the analysis of the results of the paper KÖHLER, Sebastian, et al. Clinical diagnostics in human genetics with semantic similarity searches in ontologies(1) and the improvement of them. The ... -
Análisis molecular de mutaciones en proteinas de células fotorreceptoras asociadas a retinosis pigmentaria
(ICM, 2002-12)
Article
Open Access -
Ankle sprain versus muscle strain injury in professional men's basketball: a 9-year prospective follow-up study
(2019-06-11)
Article
Open Access -
Aplicació d'eines d'anàlisi massiu de dades a l'estudi genètic de malalties complexes
(Universitat Politècnica de Catalunya, 2020-06)
Bachelor thesis
Restricted access - confidentiality agreement -
Applications of the Sinkhorn-Knopp algorithm for phylogenetic inference
(Universitat Politècnica de Catalunya, 2016-01)
Master thesis
Open AccessEn aquest treball s'estudia l'algorisme de Sinkhorn-Knopp i les seves aplicacions pel disseny de mètodes de reconstrucció filogenètica. Es dissenyen tres mètodes filogenètics ("Crossing", "$\delta$-crossing$ i Dist-crossing) ... -
AsiteDesign: a Semirational Algorithm for an Automated Enzyme Design
(American Chemical Society, 2023)
Article
Open AccessWith advances in protein structure predictions, the number of available high-quality structures has increased dramatically. In light of these advances, structure-based enzyme engineering is expected to become increasingly ... -
ATM germline variants in a young adult with chronic lymphocytic leukemia: 8 years of genomic evolution
(Springer Nature, 2022)
Article
Open Access -
Characterization of phylogenetic networks with NetTest
(2010-05-20)
Article
Open AccessBackground: Typical evolutionary events like recombination, hybridization or gene transfer make necessary the use of phylogenetic networks to properly depict the evolution of DNA and protein sequences. Although several ... -
Comparison of Tree-Child Phylogenetic Networks
(2009-11-03)
Article
Open AccessPhylogenetic networks are a generalization of phylogenetic trees that allow for the representation of nontreelike evolutionary events, like recombination, hybridization, or lateral gene transfer. While much progress has ...