Now showing items 1-6 of 6

    • Bases genético-moleculares de las distrofias de conos y bastones 

      Escoz Terzibachian, Maria Victoria (Universitat Politècnica de Catalunya, 2017-06-22)
      Master thesis
      Open Access
      Las distrofias de conos y bastones (cone-rod distrophies, CRDs), son distrofias retinianas que pertenecen al grupo de retinopatías pigmentarias. A diferencia de la retinosis pigmentaria (RP) en la que la patología retiniana ...
    • Coiled-coil conformation of a pentamidine-DNA complex 

      Moreno Chicano, Tadeo; Pous, Joan; Subirana Torrent, Juan A.; Campos López, Josefina de Lourdes (2010-03)
      Article
      Restricted access - publisher's policy
      The coiled-coil structure formed by the complex of the DNA duplex d(ATATATATAT)2 with pentamidine is presented. The duplex was found to have a mixed structure containing Watson-Crick and Hoogsteen base pairs. The drug ...
    • Estudis estructurals sobre fragments de DNA de composició 100% AT 

      Ciurans Mesa, Ruth (Universitat Politècnica de Catalunya, 2007-04)
      Master thesis (pre-Bologna period)
      Open Access
      El DNA és el component principal del material genètic de la majoria d’organismes. Es podria considerar com un magatzem d’informació que es transmet de generació en generació. Estan format per nucleòtids, constituïts d’un ...
    • Hsp90 inhibition protects against inherited retinal degeneration 

      Aguilà, Mònica; Bevilacqua, Dalila; McCulley, Caroline; Schwarz, Nele; Athanasiou, Dimitra; Kanuga, Naheed; Novoselov, Sergey S.; Lange, Clemens A.K.; Ali, Robin R.; Bainbridge, James W.; Gias, Carlos; Coffey, Peter J.; Garriga Solé, Pere; Cheetham, Michael E. (2014-04-15)
      Article
      Open Access
      The molecular chaperone Hsp90 is important for the functional maturation of many client proteins, and inhibitors are in clinical trials for multiple indications in cancer. Hsp90 inhibition activates the heat shock response ...
    • Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships 

      Sánchez, Jon; Tejero, Héctor; Fernández, José María; Juan, David; Urda García, Beatriz; Capella Gutiérrez, Salvador; Al-Shahrour, Fátima; Tabarés Seisdedos, Rafael; Baudot, Anais; Pancaldi, Vera; Valencia, Alfonso (Springer Nature, 2020)
      Article
      Open Access
      Comorbidity is a medical condition attracting increasing attention in healthcare and biomedical research. Little is known about the involvement of potential molecular factors leading to the emergence of a specific disease ...
    • Toxicogenomic analysis of environmental impact in aquatic systems 

      Navarro Cuenca, Anna (Universitat Politècnica de Catalunya, 2012-06-18)
      Doctoral thesis
      Open Access
      Field biomonitoring based on molecular biomarkers detects early warning signals of stress suffered by organisms exposed to contamination. The lower part of the Ebro River basin has a long pollution history related to the ...