Browsing by Contributor "Garcia-Parajo, Maria F."
Now showing items 1-12 of 12
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Advanced nanoscopy tools to monitor intracellular membrane trafficking
(Universitat Politècnica de Catalunya, 2021-09-09)
Master thesis
Open AccessIntracellular membrane trafficking function is to transport proteins and other macromolecules by membrane bound vesicles throughout the cell and it is key for maintaining homeostasis and responding to signaling processes. ... -
An optofluidic router in a low-cost (PDMS) platform for rapid parallel sample analysis
(Universitat Politècnica de Catalunya, 2016-09-09)
Master thesis
Open AccessOptofluidic system for (bio)chemical applications are becoming more demanding in terms of num- ber of control points, number of light sources and readout equipment. So far, most of these sys- tems require several light ... -
Fluorescence correlation spectroscopy on 2D optical antennas for single molecule studies in living cells
(Universitat Politècnica de Catalunya, 2014-09-08)
Master thesis
Open Access[ANGLÈS] The intricate molecular events that contribute for the non-homogenous and dynamic nature of the cell membrane occur at spatial and time scales which are not readily accessible by conventional microscopy techniques. ... -
Insights on the spatiotemporal organization of integrins and their ligands using quantitative biophysical tools
(Universitat Politècnica de Catalunya, 2017-03-02)
Doctoral thesis
Open AccessThe migration of leukocytes from the blood stream to sites of injury and infection in the extravascular tissues is fundamental for the immune response. Two of the main receptors mediating this process are the integrins ... -
Membrane protein nanoclustering as a functional unit of immune cells : from nanoscopy to single molecule dynamics
(Universitat Politècnica de Catalunya, 2015-10-02)
Doctoral thesis
Open AccessState-of-the-art biophysical techniques featuring high temporal and spatial resolution have allowed for the first time the direct visualization of individual transmembrane proteins on the cell membrane. These techniques ... -
Multicolor single molecule localization microscopy to monitor the organization of the golgi complex
(Universitat Politècnica de Catalunya, 2020-11-26)
Master thesis
Restricted access - author's decisionThe Golgi complex is the central organelle of the secretory pathway, where it plays akey role in protein sorting, transport and processing. Despite its huge importance, light-microscopy-based studies of the ... -
Nanophotonic antennas for enhanced single-molecule fluorescence detection and nanospectroscopy in living cells membranes
(Universitat Politècnica de Catalunya, 2017-11-10)
Doctoral thesis
Open Access
Covenantee: Aix-Marseille UniversitéSingle-molecule fluorescence spectroscopy has revolutionized the field of biophysical sciences by enabling visualization of dynamic molecular interactions and nanoscopic features with high spatiotemporal resolution. ... -
Nanoscale control of near-field interactions between single emitters and photonic antennas-on-probe
(Universitat Politècnica de Catalunya, 2020-07-27)
Doctoral thesis
Open AccessPhotonic antennas are metallic (or dielectric) nanoscale structures that convert propagating light into highly confined fields, and vice versa, in analogy to common radio antennas but on nanometric scales that lead to ... -
Novel planar photonic antennas to address the dynamic nanoarchitecture of biological membranes
(Universitat Politècnica de Catalunya, 2020-11-27)
Doctoral thesis
Open AccessThe cell membrane is the encompassing protective shield of every cell and it is composed of a multitude of proteins, lipids and other molecules. The organization of the cell membrane is inextricably intertwined with its ... -
Spatiotemporal organisation of protein nanoclusters in adhesion complexes
(Universitat Politècnica de Catalunya, 2022-02-28)
Doctoral thesis
Open AccessThe main goal of this thesis was to contribute to the understanding of the nanoscale lateral organisation of key proteins in adhesion complexes. For this, we exploited single molecule localisation-based super-resolution ... -
Towards ultrabrigth subwavelength aperture antennas for fluorescence correlation spectroscopy on living cells
(Universitat Politècnica de Catalunya, 2013-09-05)
Master thesis
Open Access[ANGLÈS] A recurring topic in cell biology has been the study of cell membrane molecules. Specifically the involvement of the distribution and dynamics of these molecules on cellular function. Several microscopy techniques ... -
Uncovering non-ergodicity on the cell membrane using single particle tracking approaches
(Universitat Politècnica de Catalunya, 2013-09-05)
Master thesis
Open Access[ANGLES] In this work, we study the diffusion on the plasma membrane of the receptor DC-SIGN. The data we used were obtained by Single Particle Tracking technique and hence consist of individual trajectories. Motivated by ...
