Browsing by Author "Gómez-Mateu, Moisés"
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Composite endpoints in clinical trials : computational tools, practical guidelines and methodological extensions
Gómez-Mateu, Moisés (Universitat Politècnica de Catalunya, 2016-06-30)
Doctoral thesis
Open AccessThe conclusions from randomized clinical trials (RCT) rely on the primary endpoint (PE), which is chosen at the design stage of the study; thus, it is of utmost importance to select it appropriately. In RCT, there should ... -
The asymptotic relative efficiency and the ratio of sample sizes when testing two different null hypotheses
Gómez, Guadalupe; Gómez-Mateu, Moisés (Institut d'Estadística de Catalunya, 2014-06-12)
Article
Open AccessComposite endpoints, consisting of the union of two or more outcomes, are often used as the primary endpoint in time-to-event randomized clinical trials. Previously, Gómez and Lagakos provided a method to guide the decision ...