Browsing by Author "Fuxe, Kjell"
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Differential expression of muscarinic acetylcholine receptor subtypes in Jurkat cells and their signaling
Alea, M.P.; Borroto Escuela, Dasiel Óscar; Romero Fernandez, Wilber; Fuxe, Kjell; Garriga Solé, Pere (2011-08-15)
Article
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Dissecting the conserved NPxxY motif of the M(3) muscarinic acetylcholine receptor: Critical role of Asp-7.49 for receptor signaling and multiprotein complex formation
Borroto Escuela, Dasiel Óscar; Romero Fernandez, Wilber; Garcia Negredo, G.; Correia, Patricia A.; Garriga Solé, Pere; Fuxe, Kjell; Ciruela, Francisco (2011)
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Diversity and bias through receptor–receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization
Fuxe, Kjell; Tarakanov, Alexander; Romero Fernández, Wilber; Ferraro, Luca; Tanganelli, Sergio; Malgorzata, Filip; Agnati, Luigi F.; Garriga Solé, Pere; Díaz Cabiale, Zaida; Borroto Escuela, Dasiel Óscar (2014-05-13)
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Open AccessAllosteric receptor–receptor interactions in GPCR heteromers appeared to introduce an intermolecular allosteric mechanism contributing to the diversity and bias in the protomers. Examples of dopamine D2R heteromerization ... -
G protein-coupled receptor heterodimerization in the brain
Borroto Escuela, Dasiel Óscar; Romero Fernandez, Wilber; Garriga Solé, Pere; Ciruela, Francisco; Narvaez, Manuel; Tarakanov, O.V.; Palkovits, Miklós; Agnati, Luigi F.; Fuxe, Kjell (2013)
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Restricted access - publisher's policyG protein-coupled receptors (GPCRs) play critical roles in cellular processes and signaling and have been shown to form heteromers with diverge biochemical and/or pharmacological activities that are different from those ... -
Preferential activation by galanin 1-15 fragment of the GalR1 protomer of a GalR1-GalR2 heteroreceptor complex
Borroto Escuela, Dasiel Óscar; Narvaez, Manuel; Di Palma, Michael; Calvo, Feliciano; Rodríguez, David; Millón, Carmelo; Carlsson, Jens; Agnati, Luigi F.; Garriga Solé, Pere; Díaz Cabiale, Zaida; Fuxe, Kjell (2014-09-26)
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Restricted access - publisher's policyThe three cloned galanin receptors show a higher affinity for galanin than for galanin N-terminal fragments. Galanin fragment (1-15) binding sites were discovered in the rat Central Nervous System, especially in dorsal ... -
The M-5 muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization
Borroto Escuela, Dasiel Óscar; Garcia Negredo, G.; Garriga Solé, Pere; Fuxe, Kjell; Ciruela, Francisco (2010-07)
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The zinc binding receptor GPR39 interacts with 5-HT1A and GalR(1) to form dynamic heteroreceptor complexes with signaling diversity
Tena Campos, Mercè; Ramon Portés, Eva; Borroto Escuela, Dasiel Óscar; Fuxe, Kjell; Garriga Solé, Pere (2015-12-01)
Article
Open AccessGPR39 is a class A G protein-coupled receptor involved in zinc binding and glucose homeostasis regulation, among other physiological processes. GPR39 was originally thought to be the receptor for obestatin peptide but this ...