Now showing items 1-3 of 3

    • Effects of aging on the biomechanical properties of the lung extracellular matrix: dependence on tissular stretch 

      Ulldemolins, Anna; Narciso, Maria; Sanz Fraile, Héctor; Otero, Jorge; Farré Ventura, Ramon; Gavara, Núria; Almendros, Isaac (Frontiers Media SA, 2024-04-05)
      Article
      Open Access
      Introduction: Aging induces functional and structural changes in the lung, characterized by a decline in elasticity and diminished pulmonary remodeling and regenerative capacity. Emerging evidence suggests that most ...
    • Silk-reinforced collagen hydrogels with raised multiscale stiffness for mesenchymal cells 3D culture 

      Sanz Fraile, Héctor; Amorós García de Valdecasas, Susana; Mendizabal, Irene; Galvez Monton, Carolina; Prat Vidal, Cristina; Bayés Genis, Antoni; Navajas Navarro, Daniel; Farré Ventura, Ramon; Otero, Jordi (2020-03-01)
      Article
      Open Access
      Type I collagen hydrogels are of high interest in tissue engineering. With the evolution of 3D bioprinting technologies, a high number of collagen-based scaffolds have been reported for the development of 3D cell cultures. ...
    • The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening 

      Andreu Arzuaga, Ion; Falcones Olarte, Bryan; Hurst, Sebastian; Chahare, Nimesh Ramesh; Quiroga Álvarez, Xarxa; Le Roux, Anabel-Lise; Kechagia, Zanetta; Beedle, Amy E.M.; Elósegui Artola, Alberto; Trepat Guixer, Xavier; Farré Ventura, Ramon (2021-07-09)
      Article
      Open Access
      Cell response to force regulates essential processes in health and disease. However, the fundamental mechanical variables that cells sense and respond to remain unclear. Here we show that the rate of force application ...