Now showing items 1-3 of 3

  • Collective cell durotaxis emerges from long-range intercellular force transmission 

    Sunyer, Raimon; Conte, Vito; Escribano, Jorge; Elosegui Artola, Alberto; Labernadie, Anna; Valon, Leo; Navajas Navarro, Daniel; Garcia Aznar, José Manuel; Muñoz Romero, José; Trepat, Xavier (2016-09-09)
    Article
    Open Access
    The ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that exhibited durotaxis even if isolated ...
  • Control of cell-cell forces and collective cell dynamics by the intercellular adhesome 

    Bazellieres, Elsa; Conte, Vito; Elosegui Artola, Alberto; Serra-Picamal, Xavier; Bintanel Morcillo, Maria; Roca Cusachs, Pere; Muñoz Romero, José; Sales Pardo, Marta; Guimerà, Roger; Trepat Guixer, Xavier (2015-04-01)
    Article
    Open Access
    Dynamics of epithelial tissues determine key processes in development, tissue healing and cancer invasion. These processes are critically influenced by cell-cell adhesion forces. However, the identity of the proteins that ...
  • Physical principles of membrane remodelling during cell mechanoadaptation 

    Casares, Laura; Elosegui Artola, Alberto; Arroyo Balaguer, Marino; Navajas, Daniel; Roca Cusachs, Pere (2015-06-01)
    Article
    Open Access
    Biological processes in any physiological environment involve changes in cell shape, which must be accommodated by their physical envelope-the bilayer membrane. However, the fundamental biophysical principles by which the ...