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  • Rational design of new class of BH3-mimetics as inhibitors of the Bcl-X(L) protein 

    Pinto Manresa, Marta; Orzaez, Maria del Mar; Delgado-Soler, L.; Pérez González, Juan Jesús; Rubio Martinez, Jaime (2011-06)
    Open Access
    The Bcl-2 family of proteins plays an important role in the intrinsic pathway of cell apoptosis. Overexpression of prosurvival members of this family of proteins is often associated with the development of many types of ...