Browsing by Contributor "Dafni, Urania"
Now showing items 1-2 of 2
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Composite endpoints in clinical trials : computational tools, practical guidelines and methodological extensions
(Universitat Politècnica de Catalunya, 2016-06-30)
Doctoral thesis
Open AccessThe conclusions from randomized clinical trials (RCT) rely on the primary endpoint (PE), which is chosen at the design stage of the study; thus, it is of utmost importance to select it appropriately. In RCT, there should ... -
Statistical efficiency of survival endpoints in breast cancer clinical trials
(Universitat Politècnica de Catalunya, 2012-07)
Master thesis
Open AccessPer demostrar l'eficàia d'una nova teràpia, en assajos clínics en càncer es recomana l'ús d'endpoints basats en la supervivència. D'entre ells, les principals agències reguladores (FDA i EMA) recomanen l'ús d' Overall ...
