Exploració per tema "Cholesterol"
Ara es mostren els items 1-13 de 13
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A well-tempered metadynamics study on free energy landscapes of melatonin bound to DMPC-cholesterol bilayers
(2019)
Text en actes de congrés
Accés restringit per política de l'editorialSmall molecules, such as melatonin (MEL, C 13 H 16 N 2 O 2 ),are essential compo- nents in biological environments. MEL’s main applications are: (1) helping to control brain function; (2) immunotherapeutic potential in ... -
Binding and dynamics of melatonin at the interface of phosphatidylcholine-cholesterol membranes
(Public Library of Science (PLOS), 2019-11-07)
Article
Accés obertThe characterization of interactions between melatonin, one main ingredient of medicines regulating sleeping rhythms, and basic components of cellular plasma membranes (phospholipids, cholesterol, metal ions and water) ... -
Effects of cholesterol on the binding of the precursor neurotransmitter tryptophan to zwitterionic membranes
(American Institute of Physics (AIP), 2018-10-28)
Article
Accés obertThe characterization of the microscopical forces between the essential a-amino-acid tryptophan, pre- cursor of the neurotransmitter serotonin and of the hormone melatonin, and the basic components of cell membranes and ... -
Effects of cholesterol on the binding of the precursor neurotransmitter tryptophan to zwitterionic membranes
(American Institute of Physics (AIP), 2018-10-25)
Article
Accés obertThe characterization of the microscopical forces between the essential a-amino-acid tryptophan, precursor of the neurotransmitter serotonin and of the hormone melatonin, and the basic components of cell membranes and their ... -
Free energy landscapes of sodium ions bound to DMPC–cholesterol membrane surfaces at infinite dilution
(2016-03-02)
Article
Accés obertExploring the free energy landscapes of metal cations on phospholipid membrane surfaces is important for the understanding of chemical and biological processes in cellular environments. Using metadynamics simulations we ... -
Free-energy surfaces of ionic adsorption in cholesterol-free and cholesterol-rich phospholipid membranes
(2017-10-23)
Article
Accés obertFree energy surfaces associated to the adsorption of metal cations ((Formula presented.), (Formula presented.), (Formula presented.), and (Formula presented.)) in biological environments have been computed by metadynamics ... -
Impact of cholesterol induced hydrophobicity on thrombosis
(Universitat Politècnica de Catalunya, 2018-01-18)
Projecte Final de Màster Oficial
Accés restringit per acord de confidencialitat -
Influence of cholesterol on the orientation of the farnesylated GTP-bound KRas-4B binding with anionic model membranes
(Multidisciplinary Digital Publishing Institute (MDPI), 2020-11-22)
Article
Accés obertThe Ras family of proteins is tethered to the inner leaflet of the cell membranes which plays an essential role in signal transduction pathways that promote cellular proliferation, survival, growth, and differentiation. ... -
Lysozyme influence on monolayers of individual and mixed lipids
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-03)
Article
Accés obertFatty acids, cholesterol, and phospholipids are amphiphilic compounds of biological interest, which form ordered monolayers mimicking biomembranes, and can be studied with the Langmuir technique using surface pressure-area ... -
Pair interactions among ternary DPPC/POPC/cholesterol mixtures in liquid-ordered and liquid-disordered phases
(2016-04-12)
Article
Accés obertSaturated phospholipids, unsaturated phospholipids, and cholesterol are essential components of cell membranes, making the understanding of their mutual interactions of great significance. We have performed microsecond ... -
PLA-PEG-Cholesterol biomimetic membrane for electrochemical sensing of antioxidants
(2024-02)
Article
Accés obertPolymeric membranes exhibit unique and modulate transport properties when they are properly functionalised, which make them ideal for ions transport, molecules separation and molecules interactions. The present work proposes ... -
Structure of benzothiadiazine at zwitterionic phospholipid cell membranes
(American Institute of Physics (AIP), 2021-10-15)
Article
Accés obertThe use of drugs derived from benzothiadiazine, which is a bicyclic heterocyclic benzene derivative, has become a widespread treatment for diseases such as hypertension (treated with diuretics such as bendroflumethiazide ... -
The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER–Golgi membrane contact sites
(Rockefeller University Press, 2020-11-06)
Article
Accés obertIn response to cholesterol deprivation, SCAP escorts SREBP transcription factors from the endoplasmic reticulum to the Golgi complex for their proteolytic activation, leading to gene expression for cholesterol synthesis ...