Now showing items 1-1 of 1

    • Intercalative DNA binding of the marine anticancer drug variolin B 

      Canals, Albert; Arribas Bosacoma, Raquel; Albericio Palomera, Fernando; Alvarez Domingo, Mercedes; Aymami Bofarull, Juan; Coll, Miquel (Macmillan Publishers, 2017-01-04)
      Open Access
      Variolin B is a rare marine alkaloid that showed promising anti-cancer activity soon after its isolation. It acts as a cyclin-dependent kinase inhibitor, although the precise mechanism through which it exerts the cytotoxic ...