Exploració per autor "Cárdenas Domínguez, Martha Ivón"
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A computational intelligence analysis of G proteincoupled receptor sequinces for pharmacoproteomic applications
Cárdenas Domínguez, Martha Ivón (Universitat Politècnica de Catalunya, 2017-09-18)
Tesi
Accés obertArguably, drug research has contributed more to the progress of medicine during the past decades than any other scientific factor. One of the main areas of drug research is related to the analysis of proteins. The world ... -
Exploratory visualization of misclassified GPCRs from their transformed unaligned sequences using manifold learning techniques
Cárdenas Domínguez, Martha Ivón; Vellido Alcacena, Alfredo; König, Caroline; Alquézar Mancho, René; Giraldo Arjonilla, Jesús (Copicentro Granada, 2014)
Text en actes de congrés
Accés obertClass C G-protein-coupled receptors (GPCRs) are cell membrane proteins of great relevance to biology and pharmacology. Previous research has revealed an upper boundary on the accuracy that can be achieved in their ... -
Manifold learning visualization of metabotropic glutamate receptors
Cárdenas Domínguez, Martha Ivón; Vellido Alcacena, Alfredo; Giraldo Arjonilla, Jesús (IOS Press, 2014)
Text en actes de congrés
Accés obertG-Protein-Coupled Receptors (GPCRs) are cell membrane proteins with a key role in biological processes. GPCRs of class C, in particular, are of great interest in pharmacology. The lack of knowledge about their 3-D structures ... -
Visual characterization of misclassified Class C GPCRs through Manifold-based machine learning methods
Cárdenas Domínguez, Martha Ivón; Vellido Alcacena, Alfredo; König, Caroline; Alquézar Mancho, René; Giraldo Arjonilla, Jesús (2015-09-18)
Article
Accés obertG-protein-coupled receptors are cell membrane proteins of great interest in biology and pharmacology. Previous analysis of Class C of these receptors has revealed the existence of an upper boundary on the accuracy that can ... -
Visual interpretation of class C GPCR subtype overlapping from the nonlinear mapping of transformed primary sequences
Cárdenas Domínguez, Martha Ivón; Vellido Alcacena, Alfredo; Giraldo Arjonilla, Jesús (Institute of Electrical and Electronics Engineers (IEEE), 2014)
Text en actes de congrés
Accés restringit per política de l'editorialThis brief paper addresses the problem of visually assessing the natural discriminability of the different subtypes that characterize class C G-Protein-Coupled Receptors, which are membrane proteins of interest in pharmacology, ...