Now showing items 1-20 of 28

    • A mathematical approach to virus therapy of glioblastomas 

      López de Rioja, Víctor; Isern, N.; Fort, J. (2016-12)
      Article
      Open Access
      It is widely believed that the treatment of glioblastomas (GBM) could benefit from oncolytic virus therapy. Clinical research has shown that Vesicular Stomatitis Virus (VSV) has strong oncolytic properties. In addition, ...
    • Action potential propagation: ion current or intramembrane electric field? 

      Martí Edo, Albert; Pérez González, Juan Jesús; Madrenas Boadas, Jordi (2018-01-22)
      Article
      Open Access
      The established action potential propagation mechanisms do not satisfactorily explain propagation on myelinated axons given the current knowledge of biological channels and membranes. The flow across ion channels presents ...
    • Analysis of homestatic regulation in cardiac cells 

      Conesa Ortega, David (Universitat Politècnica de Catalunya, 2018-06)
      Bachelor thesis
      Open Access
      Calcium ions play a leading role in heart contraction. Heart beats at a pace given by the sinoatrial node where an action potential is generated, then propagated to the rest of cardiac cells. Contractile force depends on ...
    • Cell Magnetic tweezers for the study of mechanical interactions in Cells 

      Cabedo Gómez, Aina (Universitat Politècnica de Catalunya, 2016-06-30)
      Bachelor thesis
      Open Access
      Covenantee:   King's College London
      In this project, a cell Magnetic Tweezer (MT) set-up was assembled and calibrated, aimed at the study of mechanical interactions in single cells. The set-up is able to apply forces of ranging from 0.2 to 0.5 nN and is ...
    • Development of a simulator to evaluate public health control strategies of tuberculosis in big cities 

      Gilabert Navarro, Joan Francesc (Universitat Politècnica de Catalunya, 2015-06)
      Bachelor thesis
      Open Access
      Tuberculosis is still one of the most important infectious diseases worldwide, killing over 1.5 million people each year. It is estimated that one third of world population has already been infected by Mycobacterium ...
    • Dynamics of an inchworm nano-walker 

      Alva, Aleix; Sancho, Jose Maria; Lacasta Palacio, Ana María (Elsevier Science, 2006-05-19)
      Article
      Open Access
      An inchworm processive mechanism is proposed to explain the motion of dimeric molecular motors such as kinesin.We present here preliminary results for this mechanism focusing on observables like mean velocity, coupling ...
    • Efectos de los soportes plantares sobre la termorregulación de las plantas de los pies durante la carrera 

      Gil-Calvo, M.; Universitat de València; Priego Quesada, J.I.; Lucas-Cuevas, A.G.; Jiménez-Pérez, I.; Aparicio, I.; Giménez, J.V.; Macián-Romero, C.; Llana-Belloch, S.; Pérez-Soriano, P. (Sociedad Ibérica de Biomecánica y Biomateriales, 2015)
      Article / Article
      Open Access
      Existe una gran controversia acerca de si el uso de soportes plantares puede reducir el riesgo de padecer lesiones por sobreuso en corredores. Se ha observado una relación entre las cargas plantares y la temperatura ...
    • Electromagnetic characterization of living action potential 

      Requena Pozo, Borja (Universitat Politècnica de Catalunya, 2017-05)
      Bachelor thesis
      Open Access
      Brain imaging is a vanguard and promising topic with uncountable applications in several fields. This project is driven by the development of a new brain imaging technique that could provide activity information with spatial ...
    • Front propagation speeds of T7 virus mutants 

      López de Rioja, Víctor; Fort, J.; Isern, N. (2015-11)
      Article
      Open Access
      We propose a new reaction-diffusion model with an eclipse time to study the spread of viruses on bacterial populations. This new model is both biologically and physically sound, unlike previous ones. We determine important ...
    • Implementation of cellular transport models within a multiscale simulation software 

      Hayoun-Mya, Othmane; Ponce De Leon, Miguel; Montagud, Arnau; Valencia, Alfonso (Barcelona Supercomputing Center, 2022-05)
      Conference report
      Open Access
      Agent-based models (ABM) have been increasingly employed to study dynamics of biological systems. However, these mostly lack transport mechanisms that interface between the agents and their microenvironment. We considered ...
    • Interpretabilitat de models d'aprenentatge profund en problemes de classificació d'imatges 

      Condom Tibau, Jordi Guillem (Universitat Politècnica de Catalunya, 2022-07)
      Bachelor thesis
      Open Access
      En aquest projecte s'ha desenvolupat un model d'aprenentatge profund per a la predicció d'uns fenòmens biofísics que es duen a terme a mes membranes de les cèl·lules cardíaques anomenats espícules de Calci. Depenent de com ...
    • Metabolic Cost of Traverses on Future Planetary Extra Vehicular Activities 

      Sainz Ubide, Víctor (Universitat Politècnica de Catalunya, 2020-06-29)
      Bachelor thesis
      Open Access
      Covenantee:   Texas A&M University. Department of Aerospace Engineering
      La despesa energètica per metabolisme (Metabolic Rate, MR) és una magnitud fonamental en els passejos espacials. La predicció de la despesa energètica durant una travessia futura en condicions específiques de velocitat, ...
    • Microchannel enhanced neuron-computer interface: design, fabrication, biophysics of signal generation, signal strength optimization, and its applications to ion-channel screening and basic neuroscience research 

      Wang, Ling (Universitat Politècnica de Catalunya, 2011-12-15)
      Doctoral thesis
      Open Access
      En el presente trabajo, utilizamos técnicas de microfabricación, simulaciones numéricas, experimentos de electrofisiología para explorar la viabilidad en me- jorar la interface ordenador-neurona a través de microcanales, ...
    • Microfluidic point-of-care blood panel based on a novel technique: Reversible electroosmotic flow 

      Mohammadi, Mahdi; Madadi, Hojjat; Casals Terré, Jasmina (2015-09-11)
      Article
      Open Access
      A wide range of diseases and conditions are monitored or diagnosed from blood plasma, but the ability to analyze a whole blood sample with the requirements for a point-of-care device, such as robustness, user-friendliness, ...
    • Modelos físicos de actividad cerebral: de la micro- a la macro-escala 

      Pons Rivero, Antonio Javier; García Ojalvo, Jordi (2012-09-01)
      Article
      Restricted access - publisher's policy
    • Molecular dynamics simulation of complexation between plasmid DNA and cationic peptides 

      Tsuchiya, Kousuke; Gimenez Dejoz, Joan; Numata, Keiji (Springer Nature, 2023)
      Article
      Open Access
      The elucidation of the process by which cationic peptides condense plasmid DNA (pDNA) is important for unraveling the mechanism of peptide/pDNA complex formation, which plays a vital role in gene delivery for the genetic ...
    • New indices for quantification of the power spectrum of heart rate variability time series without the need of any frequency band definition 

      Ramos Castro, Juan José; Padullés, M.; Marina, M.; Bescós, R.; Iglesias, X.; Rodriguez, F. A.; García González, Miguel Ángel; Fernández Chimeno, Mireya; Ferrer, J.; Escorihuela, R.M.; Parrado Romero, Eva; Capdevila, L.; Benitez, A.; Angulo, R. (IOP PUBLISHING LTD, 2011-06-07)
      Article
      Restricted access - publisher's policy
      This paper presents a new family of indices for the frequency domain analysis of heart rate variability time series that do not need any frequency band definition. After proper detrending of the time series, a cumulated ...
    • Optimization of a clinostat for cell growth monitoring 

      Quintana I Bistriceanu, Diana (Universitat Politècnica de Catalunya, 2023-02-01)
      Bachelor thesis
      Open Access
      Covenantee:   Universidade Federal de Pernambuco
      The effects of microgravity on organisms is an important study field expected to have plenty of applications in the future. The problem is that it is not easy at all to experiment with microgravity. The spatial missions ...
    • Physical analysis of a processive molecular motor: the conventional kinesin 

      Alva, Aleix; Lacasta Palacio, Ana María; Sancho, Jose Maria (American Physical Society, 2005-09-29)
      Article
      Open Access
      We present a model that allows for the derivation of the experimentally accesible observables: spatial steps, mean velocity, stall force, useful power, efficiency and randomness, etc. as a function of the adenosine triphosphate ...
    • Planar and cylindrical active microwave temperature imaging... 

      Rius Casals, Juan Manuel; Jofre Roca, Lluís; Broquetas Ibars, Antoni (IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 1992-12-02)
      Article
      Open Access
      A comparative study at 2.45 GHz concerning both measurement and reconstruction parameters for planar and cylindrical configurations is presented. For the sake of comparison, a numerical model consisting of two nonconcentric ...