Exploració per tema "Bioinformatics"

Ara es mostren els items 1-20 de 160

    • A compartmental model of a spiking and adapting olfactory receptor neuron 

      Ramos Garcia, Clàudia (Universitat Politècnica de Catalunya, 2010)
      Projecte/Treball Final de Carrera
      Accés restringit per acord de confidencialitat
      Realitzat a/amb:   Kungl. Tekniska högskolan. Skolan för datavetenskap och kommunikation

    • A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing 

      Alioto, Tyler S.; Buchhalter, Ivo; Derdak, Sophie; Torrents Rodas, David (2015-12-09)
      Article
      Accés obert
      As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different ...

    • A dynamic model of the proteins that form the initial iron-sulfur cluster biogenesis machinery in yeast mitochondria 

      Amela Abellán, Isaac; Delicado Useros, Pedro Francisco; Gómez, Antonio; Querol Murillo, Enrique; Cedano, J (2013-03)
      Article
      Accés restringit per política de l'editorial
      The assembly of iron-sulfur clusters (ISCs) in eukaryotes involves the protein Frataxin. Deficits in this protein have been associated with iron inside the mitochondria and impair ISC biogenesis as it is postulated to act ...

    • A framework to assess the quality and impact of bioinformatics training across ELIXIR 

      Gurwitz, Kim T.; Singh Gaur, Prakash; Bellis, Louisa J.; Larcombe, Lee; Alloza, Eva; Laszlo Balint, Balint; Botzki, Alexander; Dimec, Jure; Dominguez del Angel, Victoria; Fernandes, Pedro L.; Korpelainen, Eija; Krause, Roland; Kuzak, Mateusz; Le Pera, Loredana; Leskošek, Brane; Lindvall, Jessica M.; Marek, Diana; Martinez, Paula A.; Muyldermans, Tuur; Nygård, Ståle; Palagi, Patricia M.; Peterson, Hedi; Psomopoulos, Fotis; Spiwok, Vojtech; Gelder, Celia W. G. van; Via, Allegra; Vidak, Marko; Wibberg, Daniel; Morgan, Sarah L.; Rustici, Gabriella (Public Library of Science (PLOS), 2020-07)
      Article
      Accés obert
      ELIXIR is a pan-European intergovernmental organisation for life science that aims to coordinate bioinformatics resources in a single infrastructure across Europe; bioinformatics training is central to its strategy, which ...

    • A limited set of transcriptional programs define major cell types 

      Breschi, Alessandra; Muñoz Aguirre, Manuel; Wucher, Valentin; Guigo Serra, Roderic (2020-03-11)
      Article
      Accés obert
      We have produced RNA sequencing data for a number of primary cells from different locations in the human body. The clustering of these primary cells reveals that most cells in the human body share a few broad transcriptional ...

    • A novel MMR pathway in prokaryotes 

      Rojas, Ana (Barcelona Supercomputing Center, 2019)
      Altres
      Accés obert

    • A Tool for integrating dynamic healthcare data sources 

      Zamani Forooshani, Meysam (Universitat Politècnica de Catalunya, 2020-06-22)
      Projecte Final de Màster Oficial
      Accés obert
      Currently, there is a growing interest in finding a comprehensive method in ETL process technology that can deal with healthcare data formats. Healthcare centers are very concerned about their sensitive information which ...

    • A user guide for the online exploration and visualization of PCAWG data 

      Goldman, Mary J.; Zhang, Junjun; Fonseca, Nuno A.; Cortés-Ciriano, Isidro; Xiang, Qian; Craft, Brian; Piñeiro-Yáñez, Elena; O'connor, Brian D.; Bazant, Wojciech; Barrera, Elisabet; Muñoz-Pomer, Alfonso; Petryszak, Robert; Füllgrabe, Anja; Al-Shahrour, Fatima; Keays, Maria; Haussler, David; Weinstein, John N; Huber, Wolfgang; Park, Peter J.; Papatheodorou, Elena; Valencia, Alfonso; Zhu, Jingchun; Ferretti, Vincent; Vazquez, Miguel (Springer Nature, 2020)
      Article
      Accés obert
      The Pan-Cancer Analysis of Whole Genomes (PCAWG) project generated a vast amount of whole-genome cancer sequencing resource data. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which ...

    • A workflow for the analysis and modelling of high-dimensional omics data 

      Otero Martín, Gerard (Universitat Politècnica de Catalunya, 2019-09)
      Treball Final de Grau
      Accés obert
      En los últimos años, los avances en el campo de la computación han convertido al Machine Learning en un método viable para obtener información muy precisa y hacer grandes predicciones relacionadas con todo el campo de la ...

    • Accelerating binding free energy calculations by combining Monte Carlo simulations, enhanced sampling and Markov State Models 

      Gilabert, Joan F.; Guallar, Victor (Barcelona Supercomputing Center, 2018-04-24)
      Text en actes de congrés
      Accés obert

    • Accelerating K-mer Frequency Counting with GPU and Non-Volatile Memory 

      Cadenelli, Nicola; Polo Cantero, José; Carrera Pérez, David (2018)
      Text en actes de congrés
      Accés obert
      The emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its ...

    • Accelerating K-mer Frequency Counting with GPU and Non-Volatile Memory 

      Cadenelli, Nicola; Polo Bardés, Jordà; Carrera, David (IEEE, 2018-02-15)
      Comunicació de congrés
      Accés obert
      The emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its ...

    • Accelerating pairwise sequence alignment on GPUs using the Wavefront Algorithm 

      Aguado Puig, Quim (Universitat Politècnica de Catalunya, 2022-10-19)
      Projecte Final de Màster Oficial
      Accés obert
      Advances in genomics and sequencing technologies demand faster and more scalable analysis methods that can process longer sequences with higher accuracy. However, classical pairwise alignment methods, based on dynamic ...

    • Algorismes bioinformàtics utilitzant HMMs 

      García Roca, Marta (Universitat Politècnica de Catalunya, 2007-01-26)
      Projecte/Treball Final de Carrera
      Accés obert

    • AligNet: alignment of protein-protein interaction networks 

      Alcala Mena, Adrià; Alberich Martí, Ricardo; Llabrés Segura, Mercè; Rosselló Llompart, Francesc A.; Valiente Feruglio, Gabriel Alejandro (2020-11-18)
      Article
      Accés obert
      Background: All molecular functions and biological processes are carried out by groups of proteins that interact with each other. Metaproteomic data continuously generates new proteins whose molecular functions and relations ...

    • An FPGA accelerator of the wavefront algorithm for genomics pairwise alignment 

      Haghi, Abbas; Marco-Sola, Santiago; Álvarez Martí, Lluc; Diamantopoulos, Dionysios; Hagleitner, Christoph; Moretó Planas, Miquel (Institute of Electrical and Electronics Engineers (IEEE), 2021)
      Text en actes de congrés
      Accés obert
      In the last years, advances in next-generation sequencing technologies have enabled the proliferation of genomic applications that guide personalized medicine. These applications have an enormous computational cost due to ...

    • An optimized TOPS+ comparison method for enhanced TOPS models 

      Veeramalai, Mallika; Gilbert, David; Valiente Feruglio, Gabriel Alejandro (2010-03-17)
      Article
      Accés obert
      Background: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a high degree of biological significance. ...

    • Analysis of incomplete gene expression dataset through protein-protein interaction information 

      Massanet Vila, Raimon; Padró Capmany, Teresa; Cardús, Anna; Badimón, Lina; Caminal Magrans, Pere; Perera Lluna, Alexandre (2011)
      Text en actes de congrés
      Accés restringit per política de l'editorial
      This paper shows a graph based method to analyze proteomic expression data. The method allows the prediction of the expression of genes not measured by the gene expression technology based on the local connectivity properties ...

    • Anàlisi i optimització de l'aplicació bioinformàtica de docking: Lightdock 

      Vidal, Miquel (Universitat Politècnica de Catalunya, 2015-01-26)
      Treball Final de Grau
      Accés obert
      [CATALÀ] En aquest projecte es realitza una anàlisi de Lightdock, una aplicació de protein docking, i es detallen un seguit d'optimitzacions amb l'objectiu de reduir del temps d'execució del programa. Finalment es proposen ...

    • Análisis de aplicaciones bioinformáticas en un procesador vectorial 

      Mesas Atero, Daniel (Universitat Politècnica de Catalunya, 2007-01-26)
      Projecte/Treball Final de Carrera
      Accés obert