Now showing items 1-20 of 112

  • Accelerating binding free energy calculations by combining Monte Carlo simulations, enhanced sampling and Markov State Models 

    Gilabert, Joan F.; Guallar, Victor (Barcelona Supercomputing Center, 2018-04-24)
    Conference report
    Open Access
  • Accelerating K-mer Frequency Counting with GPU and Non-Volatile Memory 

    Cadenelli, Nicola; Polo, Jordà; Carrera, David (IEEE, 2018-02-15)
    Conference lecture
    Open Access
    The emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its ...
  • Accelerating K-mer Frequency Counting with GPU and Non-Volatile Memory 

    Cadenelli, Nicola; Polo Cantero, José; Carrera Pérez, David (2018)
    Conference report
    Open Access
    The emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its ...
  • A compartmental model of a spiking and adapting olfactory receptor neuron 

    Ramos Garcia, Clàudia (Universitat Politècnica de Catalunya, 2010)
    Master thesis (pre-Bologna period)
    Restricted access - confidentiality agreement
    Covenantee:  Kungl. Tekniska högskolan. Skolan för datavetenskap och kommunikation
  • A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing 

    Alioto, Tyler S.; Buchhalter, Ivo; Derdak, Sophie; Torrents Rodas, David (2015-12-09)
    Article
    Open Access
    As whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different ...
  • A dynamic model of the proteins that form the initial iron-sulfur cluster biogenesis machinery in yeast mitochondria 

    Amela Abellán, Isaac; Delicado Useros, Pedro Francisco; Gómez, Antonio; Querol Murillo, Enrique; Cedano, J (2013-03)
    Article
    Restricted access - publisher's policy
    The assembly of iron-sulfur clusters (ISCs) in eukaryotes involves the protein Frataxin. Deficits in this protein have been associated with iron inside the mitochondria and impair ISC biogenesis as it is postulated to act ...
  • Algorismes bioinformàtics utilitzant HMMs 

    García Roca, Marta (Universitat Politècnica de Catalunya, 2007-01-26)
    Master thesis (pre-Bologna period)
    Open Access
  • Anàlisi i optimització de l'aplicació bioinformàtica de docking: Lightdock 

    Vidal-Piñol, Miquel (Universitat Politècnica de Catalunya, 2015-01-26)
    Bachelor thesis
    Open Access
    [CATALÀ] En aquest projecte es realitza una anàlisi de Lightdock, una aplicació de protein docking, i es detallen un seguit d'optimitzacions amb l'objectiu de reduir del temps d'execució del programa. Finalment es proposen ...
  • Análisis de aplicaciones bioinformáticas en un procesador vectorial 

    Mesas Atero, Daniel (Universitat Politècnica de Catalunya, 2007-01-26)
    Master thesis (pre-Bologna period)
    Open Access
  • Análisis del ECG para la detección automática del patrón característico del síndrome de Brugada 

    Calvo González, Mireia; Gomis Román, Pedro; Andreu Caballero, Daniel; Caminal Magrans, Pere; Arbelo Lainez, Elena (2014)
    Conference lecture
    Open Access
    El síndrome de Brugada es una enfermedad hereditaria caracterizada por un patrón electrocardiográfico característico, así como por un aumento del riesgo de sufrir arritmias cardíacas y muerte súbita. No existen actualmente ...
  • Análisis vibracional de proteínas en coordenadas internas mediante el modelo ANM 

    Rincón Muñoz, Alba (Universitat Politècnica de Catalunya, 2014-12-17)
    Master thesis (pre-Bologna period)
    Open Access
    PELE es un software que explora el espacio conformacional de las proteínas, la implementación del movimiento está hecha con el modelo ANM en coordenadas internas. El proyecto tiene como objetivo su desarrollo usando las ...
  • Analysis of incomplete gene expression dataset through protein-protein interaction information 

    Massanet Vila, Raimon; Padró Capmany, Teresa; Cardús, Anna; Badimón, Lina; Caminal Magrans, Pere; Perera Lluna, Alexandre (2011)
    Conference report
    Restricted access - publisher's policy
    This paper shows a graph based method to analyze proteomic expression data. The method allows the prediction of the expression of genes not measured by the gene expression technology based on the local connectivity properties ...
  • An optimized TOPS+ comparison method for enhanced TOPS models 

    Veeramalai, Mallika; Gilbert, David; Valiente Feruglio, Gabriel Alejandro (2010-03-17)
    Article
    Open Access
    Background: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a high degree of biological significance. ...
  • A novel MMR pathway in prokaryotes 

    Rojas, Ana (Barcelona Supercomputing Center, 2019)
    Other
    Open Access
  • Aplicació bioinformàtica per al descobriment de nous fàrmacs 

    Otón Pàmies, Marcel (Universitat Politècnica de Catalunya, 2013-11-08)
    Master thesis (pre-Bologna period)
    Open Access
    El meu projecte de final de carrera consisteix en la implementació d’una eina informàtica anomenada SEABED (Small molEcule Activity scanner web-service Based on Ensemble Docking). Aquesta eina web serà utilitzada per la ...
  • Automating installation, testing and development of bcbio-nextgen pipeline 

    Carrasco Hernandez, Guillermo (Universitat Politècnica de Catalunya, 2013-06-26)
    Master thesis (pre-Bologna period)
    Open Access
    In the recent years, the costs of obtaining biological data have been drastically reduced. This has lead into an exponential growth of the available data. Having such growth of data to analyze sometimes results in ...
  • BIGNASim: a NoSQL database structure and analysis portal for nucleic acids simulation data 

    Hospital, Adam; Andrio, Pau; Cugnasco, Cesare; Codo, Laia; Becerra Fontal, Yolanda; Dans, Pablo D.; Battistini, Federica; Torres Viñals, Jordi; Goñi, Ramon; Orozco, Modesto; Gelpí, Josep Lluís (2016-01-04)
    Article
    Open Access
    Molecular dynamics simulation (MD) is, just behind genomics, the bioinformatics tool that generates the largest amounts of data, and that is using the largest amount of CPU time in supercomputing centres. MD trajectories ...
  • Bioinformática 

    Barceló Garcia, Miquel (2000-10)
    Article
    Open Access
  • Bioinformatics and medicine in the era of deep learning 

    Bacciu, Davide; Lisboa, Paulo J G; Martín, José David; Stoean, Ruxandra; Vellido Alcacena, Alfredo (I6doc.com, 2018)
    Conference report
    Restricted access - publisher's policy
    Many of the current scientific advances in the life sciences have their origin in the intensive use of data for knowledge discovery. In no area this is so clear as in bioinformatics, led by technological breakthroughs in ...
  • Bioinformatics: a promising field for case-based reasoning 

    Orduña Cabrera, Fernando; Sànchez-Marrè, Miquel (2008-06)
    External research report
    Open Access
    Case Based Reasoning has been applied in different fields such as medicine, industry, tutoring systems and others, but in the CBR there are many areas to explore. Nowadays, some research works in Bioinformatics are attempting ...