Browsing by Subject "Bioinformàtica"
Now showing items 1-20 of 148
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A compartmental model of a spiking and adapting olfactory receptor neuron
(Universitat Politècnica de Catalunya, 2010)
Master thesis (pre-Bologna period)
Restricted access - confidentiality agreement
Covenantee: Kungl. Tekniska högskolan. Skolan för datavetenskap och kommunikation -
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
(2015-12-09)
Article
Open AccessAs whole-genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Here using tumour-normal sample pairs from two different ... -
A limited set of transcriptional programs define major cell types
(2020-03-11)
Article
Open AccessWe have produced RNA sequencing data for a number of primary cells from different locations in the human body. The clustering of these primary cells reveals that most cells in the human body share a few broad transcriptional ... -
A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma
(Springer Nature, 2023)
Article
Open AccessTherapy Induced Senescence (TIS) leads to sustained growth arrest of cancer cells. The associated cytostasis has been shown to be reversible and cells escaping senescence further enhance the aggressiveness of cancers. ... -
A novel MMR pathway in prokaryotes
(Barcelona Supercomputing Center, 2019)
Other
Open Access -
A theoretical approach to the engineering of bioinspired systems: design, applications & information management
(Universitat Politècnica de Catalunya, 2011-02-17)
Doctoral thesis
Open AccessL’enginyeria de sistemes bioinspirats ha crescut en importància i nombre d’aplicacions en el últims anys, atraient l’atenció dels científics sobre els seus usos potencials en camps com ara la bionanotecnologia, la ... -
A Tool for integrating dynamic healthcare data sources
(Universitat Politècnica de Catalunya, 2020-06-22)
Master thesis
Open AccessCurrently, there is a growing interest in finding a comprehensive method in ETL process technology that can deal with healthcare data formats. Healthcare centers are very concerned about their sensitive information which ... -
A user guide for the online exploration and visualization of PCAWG data
(Springer Nature, 2020)
Article
Open AccessThe Pan-Cancer Analysis of Whole Genomes (PCAWG) project generated a vast amount of whole-genome cancer sequencing resource data. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which ... -
A Web-based tool for training radiologists in medical imaging
(2013)
Conference report
Restricted access - publisher's policy -
A workflow for the analysis and modelling of high-dimensional omics data
(Universitat Politècnica de Catalunya, 2019-09)
Bachelor thesis
Open AccessEn los últimos años, los avances en el campo de la computación han convertido al Machine Learning en un método viable para obtener información muy precisa y hacer grandes predicciones relacionadas con todo el campo de la ... -
Accelerating binding free energy calculations by combining Monte Carlo simulations, enhanced sampling and Markov State Models
(Barcelona Supercomputing Center, 2018-04-24)
Conference report
Open Access -
Accelerating K-mer Frequency Counting with GPU and Non-Volatile Memory
(2018)
Conference report
Open AccessThe emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its ... -
Accelerating pairwise sequence alignment on GPUs using the Wavefront Algorithm
(Universitat Politècnica de Catalunya, 2022-10-19)
Master thesis
Open AccessAdvances in genomics and sequencing technologies demand faster and more scalable analysis methods that can process longer sequences with higher accuracy. However, classical pairwise alignment methods, based on dynamic ... -
Acinetobacter type VI secretion system comprises a non-canonical membrane complex
(Public Library of Science, 2023-09)
Article
Open AccessA. baumannii can rapidly acquire new resistance mechanisms and persist on abiotic surface, enabling the colonization of asymptomatic human host. In Acinetobacter the type VI secretion system (T6SS) is involved in twitching, ... -
Algorismes bioinformàtics utilitzant HMMs
(Universitat Politècnica de Catalunya, 2007-01-26)
Master thesis (pre-Bologna period)
Open Access -
AligNet: alignment of protein-protein interaction networks
(2020-11-18)
Article
Open AccessBackground: All molecular functions and biological processes are carried out by groups of proteins that interact with each other. Metaproteomic data continuously generates new proteins whose molecular functions and relations ... -
An FPGA accelerator of the wavefront algorithm for genomics pairwise alignment
(Institute of Electrical and Electronics Engineers (IEEE), 2021)
Conference report
Open AccessIn the last years, advances in next-generation sequencing technologies have enabled the proliferation of genomic applications that guide personalized medicine. These applications have an enormous computational cost due to ... -
An optimized TOPS+ comparison method for enhanced TOPS models
(2010-03-17)
Article
Open AccessBackground: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a high degree of biological significance. ... -
An R package to analyse LC/MS metabolomic data: MAIT (Metabolite Automatic Identification Toolkit).
(2014-03-17)
Article
Restricted access - publisher's policy -
Anàlisi i optimització de l'aplicació bioinformàtica de docking: Lightdock
(Universitat Politècnica de Catalunya, 2015-01-26)
Bachelor thesis
Open Access[CATALÀ] En aquest projecte es realitza una anàlisi de Lightdock, una aplicació de protein docking, i es detallen un seguit d'optimitzacions amb l'objectiu de reduir del temps d'execució del programa. Finalment es proposen ...
