Now showing items 1-7 of 7

  • A single-residue substitution inhibits fibrillization of Ala-based pentapeptides. A spectroscopic and molecular dynamics investigation 

    Caruso, M.; Gatto, Emanuela; Placidi, E.; Venanzi, Mariano; Ballano Ballano, María Gema; Formaggio, Fernando; Toniolo, Claudio; Zanuy Gomara, David; Alemán Llansó, Carlos (2014-01-01)
    Article
    Open Access
    The aggregation properties of two Ala-based pentapeptides were investigated by spectroscopic techniques and molecular dynamics (MD) simulations. The two peptides, both functionalized at the N-terminus with a pyrenyl group, ...
  • Effect of solvent choice on the self-assembly properties of a diphenylalanine amphiphile stabilized by an ion pair 

    Mayans Tayadella, Enric; Ballano Ballano, María Gema; Sendros, Javier; Font Bardia, Mercè; Campos López, Josefina de Lourdes; Puiggalí Bellalta, Jordi; Cativiela, Carlos; Alemán Llansó, Carlos (2017-07-19)
    Article
    Restricted access - publisher's policy
    A diphenylalanine (FF) amphiphile blocked at the C terminus with a benzyl ester (OBzl) and stabilized at the N terminus with a trifluoroacetate (TFA) anion was synthetized and characterized. Aggregation of peptide molecules ...
  • Electro-biocompatibility of conjugates designed by chemical similarity 

    Maione, Silvana; Fabregat Jové, Georgina; Valle Mendoza, Luis Javier del; Ballano Ballano, María Gema; Cativiela, Carlos; Alemán Llansó, Carlos (2014-07-01)
    Article
    Restricted access - publisher's policy
    The roughness and thickness of films formed by hybrid conjugates prepared by coupling poly(3,4-ethylenedioxythiophene) and synthetic amino acids bearing a 3,4-ethylenedioxythiophene group in the side chain have been ...
  • Engineering strategy to improve peptide analogs: from structure-based computational design to tumor homing 

    Zanuy Gomara, David; Sayago García, Francisco Javier; Revilla López, Guillermo; Ballano Ballano, María Gema; Agemy, Lilach; Kotamraju, Venkata Ramana; Jimenez, Ana I.; Cativiela, Carlos; Nussinov, Ruth; Sawvel, April M.; Ruoslahti, Erkki; Stucky, Galen; Alemán Llansó, Carlos (2013-01)
    Article
    Restricted access - publisher's policy
    We present a chemical strategy to engineer analogs of the tumor-homing peptide CREKA (Cys-Arg- Glu-Lys-Ala), which binds to fibrin and fibrin-associated clotted plasma proteins in tumor vessels (Simberg et al. in Proc ...
  • Hierarchical self-assembly of di-, tri- and tetraphenylalanine peptides capped with two fluorenyl functionalities: from polymorphs to dendrites 

    Mayans Tayadella, Enric; Ballano Ballano, María Gema; Casanovas Muñoz, Jordi; Valle Mendoza, Luis Javier del; Pérez Madrigal, Mª del Mar; Estrany Coda, Francesc; Jimenez Sanz, Ana Isabel; Puiggalí Bellalta, Jordi; Cativiela, Carlos; Alemán Llansó, Carlos (2016)
    Article
    Open Access
    Homopeptides with 2, 3 and 4 phenylalanine (Phe) residues and capped with fluorenylmethoxycarbonyl and fluorenylmethyl esters at the N-terminus and C-terminus, respectively, have been synthesized to examine their self-assembly ...
  • Self-assembly of diphenylalanine with preclick components as capping groups 

    Gemma, Andrea; Mayans Tayadella, Enric; Ballano Ballano, María Gema; Torras Costa, Juan; Díaz Andrade, Angélica María; Jimenez Sanz, Ana Isabel; Puiggalí Bellalta, Jordi; Cativiela Marín, Carlos A.; Alemán Llansó, Carlos (2017-01-01)
    Article
    Open Access
    Alkyne and azide, which are commonly used in the cycloaddition reaction recognized as “click chemistry”, have been used as capping groups of two engineered diphenylalanine (FF) derivatives due to their ability to form weak ...
  • Self-assembly of tetraphenylalanine peptides 

    Mayans Tayadella, Enric; Ballano Ballano, María Gema; Casanovas Salas, Jordi; Díaz Andrade, Angélica María; Pérez Madrigal, Maria del Mar; Estrany Coda, Francesc; Puiggalí Bellalta, Jordi; Cativiela Marín, Carlos A.; Alemán Llansó, Carlos (2015-11-01)
    Article
    Restricted access - publisher's policy
    Three different tetraphenylalanine (FFFF) based peptides that differ at the N- and C-termini have been synthesized by using standard procedures to study their ability to form different nanoassemblies under a variety of ...