Browsing by Author "Alves, Paula M."
Now showing items 1-3 of 3
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3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment
(2018-05)
Article
Open AccessThe tumour microenvironment (TME) shapes disease progression and influences therapeutic response.Most aggressive solid tumours have high levels of myeloid cell infiltration, namely tumour associatedmacrophages (TAM). ... -
Imaging of human differentiated 3D neural aggregates using light sheet fluorescence microscopy
(2014-08-06)
Article
Open AccessThe development of three dimensional (3D) cell cultures represents a big step for the better understanding of cell behavior and disease in a more natural like environment, providing not only single but multiple cell type ... -
Modelling the tumour microenvironment in long-term microencapsulated 3D co-cultures recapitulates phenotypic features of disease progression
(2016-02)
Article
Open Access3D cell tumour models are generated mainly in non-scalable culture systems, using bioactive scaffolds. Many of these models fail to reflect the complex tumour microenvironment and do not allow long-term monitoring of ...
