Browsing by Author "Alcalde, Miguel"
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Mapping potential determinants of peroxidative activity in an evolved fungal peroxygenase from agrocybe aegerita
Molina Espeja, Patricia; Beltran Nogal, Alejandro; Alfuzzi, Maria Alejandra; Guallar, Victor; Alcalde, Miguel (Frontiers Media, 2021)
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Open AccessFungal unspecific peroxygenases (UPOs) are hybrid biocatalysts with peroxygenative activity that insert oxygen into non-activated compounds, while also possessing convergent peroxidative activity for one electron oxidation ... -
Oxidoreductases on their way to industrial biotransformations
Martinez, Angel T.; Ruiz-Dueñas, Francisco; Camarero, Susana; Serrano, Ana; Linde, Dolores; Lund, Henrik; Vind, Jesper; Tovborg, Morten; Herold-Majumdar, Owik M.; Hofrichter, Martin; Liers, Christiane; Ullrich, René; Scheibner, Katrin; Sannia, Giovanni; Piscitelli, Alessandra; Pezzella, Cinzia; Sener, Mehmet E.; Kiliç, Sibel; van Berkel, Willhem J.H.; Guallar, Victor; Lucas, Fátima; Zuhse, Ralf; Ludwig, Roland; Hollmann, Frank; Fernández-Fueyo, Elena; Record, Eric; Faulds, Craig B.; Tortajada, Marta; Winckelmann, Ib; Rasmussen, Jo-Anne; Gelo-Pujic, Mirjana; Gutiérrez, Ana; del Río, José C.; Rencoret, Jorge; Alcalde, Miguel (Elsevier, 2017-11)
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Open AccessFungi produce heme-containing peroxidases and peroxygenases, flavin-containing oxidases and dehydrogenases, and different copper-containing oxidoreductases involved in the biodegradation of lignin and other recalcitrant ... -
Sequential oxidation of 5-hydroxymethylfurfural to furan-2,5-dicarboxylic acid by an evolved aryl-alcohol oxidase
Viña-Gonzalez, Javier; Martinez, Angel T.; Guallar, Víctor; Alcalde, Miguel (Elsevier, 2020)
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Open AccessFuran-2,5-dicarboxylic acid (FDCA) is a building block of biodegradable plastics that can be used to replace those derived from fossil carbon sources. In recent years, much interest has focused on the synthesis of FDCA ... -
Switching the substrate preference of fungal aryl-alcohol oxidase: towards stereoselective oxidation of secondary benzyl alcohols
Serrano, Ana; Sancho, Ferran; Viña-González, Javier; Carro, Juan; Alcalde, Miguel; Guallar, Victor; Martínez, Angel T. (Royal Society of Chemistry, 2019-01-22)
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Open AccessOxidation of primary alcohols by aryl-alcohol oxidase (AAO), a flavoenzyme that provides H2O2 to fungal peroxidases for lignin degradation in nature, is achieved by concerted hydroxyl proton transfer and stereoselective ... -
Synthesis of 1‐Naphthol by a Natural Peroxygenase engineered by Directed Evolution
Molina-Espeja, Patricia; Cañellas, Marina; Plou, Francisco J.; Hofrichter, Martin; Lucas, Fatima; Guallar, Victor; Alcalde, Miguel (Wiley-VCH, 2016-01-21)
Article
Open AccessThere is an increasing interest in enzymes that catalyze the hydroxylation of naphthalene under mild conditions and with minimal requirements. To address this challenge, an extracellular fungal aromatic peroxygenase with ...