Listar por tema "(-)-epigallocatechin-3-gallate"

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Combined treatment with environmental enrichment and (-)-epigallocatechin-3-gallate ameliorates learning deficits and hippocampal alterations in a mouse model of Down Syndrome

Catuara-Solarz, Silvina; Espinoa Carrasco, Jose; Erb, Ionas; Langohr, Klaus; González, Juan Ramon; Notredame, Cedric; Dierssen, Mara (2016-11-08)
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Intellectual disability in Down syndrome (DS) is accompanied by altered neuro-architecture, deficient synaptic plasticity, and excitation-inhibition imbalance in critical brain regions for learning and memory. Recently, ...
Principal component analysis of the effects of environmental enrichment and (-)-epigallocatechin-3-gallate on age-associated learning deficits in a mouse model of Down Syndrome

Catuara, Silvina; Espinosa Carrasco, Jose; Erb, Ionas; Langohr, Klaus; Notredame, Cedric; Gonzalez, Juan R.; Dierssen, Mara (2015-12-11)
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Down syndrome (DS) individuals present increased risk for Alzheimer's disease (AD) neuropathology and AD-type dementia. Here, we investigated the use of green tea extracts containing (-)-epigallocatechin-3-gallate (EGCG), ...