• Accelerating the hierarchical multi-scale software by spatial clustering strategies 

      Khairullah, Md; Gawad, Jerzy; Roose, Dirk; Bael, Albertan (CIMNE, 2015)
      Comunicació de congrés
      Accés obert
      In multi-scale simulations of material forming processes, macroscopic zones of nearly homogeneous strain response can be observed. In such zones the evolution of material properties at each finite element integration point ...
    • BioFVM-X: an MPI+OpenMP 3-D simulator for biological systems 

      Saxena, Gaurav; Ponce De Leon, Miguel; Montagud, Arnau; Vicente Dorca, David; Valencia, Alfonso (Springer, 2021)
      Text en actes de congrés
      Accés obert
      Multi-scale simulations require parallelization to address large-scale problems, such as real-sized tumor simulations. BioFVM is a software package that solves diffusive transport Partial Differential Equations for 3-D ...
    • Implementation of cellular transport models within a multiscale simulation software 

      Hayoun-Mya, Othmane; Ponce De Leon, Miguel; Montagud, Arnau; Valencia, Alfonso (Barcelona Supercomputing Center, 2022-05)
      Text en actes de congrés
      Accés obert
      Agent-based models (ABM) have been increasingly employed to study dynamics of biological systems. However, these mostly lack transport mechanisms that interface between the agents and their microenvironment. We considered ...
    • Optimizing dosage-specific treatments in a multi-Scale model of a tumor growth 

      Ponce De Leon, Miguel; Montagud, Arnau; Akasiadis, Charilaos; Schreiber, Janina; Ntiniakou, Thaleia; Valencia, Alfonso (Frontiers Media, 2022-04)
      Article
      Accés obert
      The emergence of cell resistance in cancer treatment is a complex phenomenon that emerges from the interplay of processes that occur at different scales. For instance, molecular mechanisms and population-level dynamics ...