Browsing by Subject "G protein-coupled receptors"
Now showing items 1-8 of 8
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Advanced mathematics for new therapeutics: a proposal for chronic pain
(Universitat Politècnica de Catalunya, 2022-10)
Master thesis
Open AccessG protein-coupled receptors are membrane proteins that transmit signals inside the cell by the interaction of neurotransmitters, hormones, and synthetic molecules. These proteins may be present in the membrane forming ... -
Characterization of amino acid changes in visual pigment evolution and interaction with associated proteins
(Universitat Politècnica de Catalunya, 2018-06-11)
Doctoral thesis
Open AccessVisual opsins are G protein-coupled receptors that function as light photoreceptors in the vertebrate retina. Rhodopsin is the visual pigment located in the rod photoreceptor cells specialized in scotopic vision. Bovine ... -
Mathematical analysis of desensitization of G protein-coupled receptors
(Universitat Politècnica de Catalunya, 2021-07)
Master thesis
Open AccessG protein-coupled receptors are integral membrane proteins responsible for signal transduction from outside to inside the cell, and the study of their functional conditions may determine the healthy or pathological state ... -
New insights into the molecular mechanism of rhodopsin retinitis pigmentosa from the biochemical and functional characterization of G90V, Y102H and I307N mutations
(Springer Nature, 2022-01-01)
Article
Open AccessMutations in the photoreceptor protein rhodopsin are known as one of the leading causes of retinal degeneration in humans. Two rhodopsin mutations, Y102H and I307N, obtained in chemically mutagenized mice, are currently ... -
Protein classification from primary structures in the context of database biocuration
(Universitat Politècnica de Catalunya, 2017-04)
Master thesis
Open AccessThe problem of automatic protein classification using only their primary structures plays an important role in modern bioinformatics research, especially for proteins whose 3-D structures are yet unknown. One of these ... -
Recognition of conformational states of a G protein coupled receptor from molecular dynamic simulations using sampling techniques
(Springer, 2023)
Conference report
Open AccessProtein structures are complex and dynamic entities relevant to many biological processes. G-protein-coupled receptors in particular are a functionally relevant family of cell membrane proteins of interest as targets in ... -
Reducing the n-gram feature space of class C GPCRs to subtype-discriminating patterns
(2014-10-23)
Article
Open AccessG protein-coupled receptors (GPCRs) are a large and heterogeneous superfamily of receptors that are key cell players for their role as extracellular signal transmitters. Class C GPCRs, in particular, are of great interest ...
