Browsing by Subject "G protein-coupled receptor"
Now showing items 1-4 of 4
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Diversity and bias through receptor–receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization
(2014-05-13)
Article
Open AccessAllosteric receptor–receptor interactions in GPCR heteromers appeared to introduce an intermolecular allosteric mechanism contributing to the diversity and bias in the protomers. Examples of dopamine D2R heteromerization ... -
Effect of sodium valproate on the conformational stability of the visual G Protein-coupled receptor rhodopsin
(2021-05-19)
Article
Open AccessRhodopsin is the G protein-coupled receptor of rod photoreceptor cells that mediates vertebrate vision at low light intensities. Mutations in rhodopsin cause inherited retinal degenerative diseases such as retinitis ... -
Human blue cone opsin regeneration involves secondary retinal binding with analog specificity
(2018-03-27)
Article
Open AccessHuman color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein covalently linked to the 11-cis-retinal chromophore. All visual ... -
The zinc binding receptor GPR39 interacts with 5-HT1A and GalR(1) to form dynamic heteroreceptor complexes with signaling diversity
(2015-12-01)
Article
Open AccessGPR39 is a class A G protein-coupled receptor involved in zinc binding and glucose homeostasis regulation, among other physiological processes. GPR39 was originally thought to be the receptor for obestatin peptide but this ...
