Exploració per tema "Cardiac tissue engineering"
Ara es mostren els items 1-4 de 4
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A microphysiological system combining electrospun fibers and electrical stimulation for the maturation of highly anisotropic cardiac tissue
(2021-06-01)
Article
Accés oberthe creation of cardiac tissue models for preclinical testing is still a non-solved problem in drug discovery, due to the limitations related to the in vitro replication of cardiac tissue complexity. Among these limitations, ... -
Electrical stimulation of cardiac adipose tissue-derived progenitor cells modulates cell phenotype and genetic machinery
(2015-11)
Article
Accés obertA major challenge of cardiac tissue engineering is directing cells to establish the physiological structure and function of the myocardium being replaced. Our aim was to examine the effect of electrical stimulation on the ... -
Engineered macroscale cardiac constructs elicit human myocardial tissue-like functionality
(2019-07-09)
Article
Accés obertIn vitro surrogate models of human cardiac tissue hold great promise in disease modeling, cardiotoxicity testing, and future applications in regenerative medicine. However, the generation of engineered human cardiac ... -
The generation of a lactate-rich environment stimulates cell cycle progression and modulates gene expression on neonatal and hiPSC-derived cardiomyocytes
(Elsevier, 2022-08)
Article
Accés obertIn situ tissue engineering strategies are a promising approach to activate the endogenous regenerative potential of the cardiac tissue helping the heart to heal itself after an injury. However, the current use of complex ...