Exploració per tema "Cancer cells"
Ara es mostren els items 1-18 de 18
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A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma
(Springer Nature, 2023)
Article
Accés obertTherapy Induced Senescence (TIS) leads to sustained growth arrest of cancer cells. The associated cytostasis has been shown to be reversible and cells escaping senescence further enhance the aggressiveness of cancers. ... -
Antibacterial and antiproliferative activities of Azadirachta indica leaf extract and its effect on oil-in-water food emulsion stability
(2022-11-11)
Article
Accés obertThe present study aims to identify and quantify the phenolic compounds of Azadirachta indica leaf extract using HPLC-MS and to evaluate the antioxidant, antibacterial (against different Gram-positive and negative bacteria) ... -
Antiproliferative activity and mode of action analysis of novel amino and amido substituted phenantrene and naphtho[2,1-b]thiophene derivatives
(Elsevier, 2019)
Article
Accés obertHerein we present and describe the design and synthesis of novel phenantrene derivatives substituted with either amino or amido side chains and their biological activity. Antiproliferative activities were assessed in vitro ... -
Collective cell durotaxis emerges from long-range intercellular force transmission
(2016-09-09)
Article
Accés obertThe ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that exhibited durotaxis even if isolated ... -
Computational analysis of sense-antisense chimeric transcripts reveals their potential regulatory features and the landscape of expression in human cells
(Oxford University Press, 2021-08)
Article
Accés obertMany human genes are transcribed from both strands and produce sense-antisense gene pairs. Sense-antisense (SAS) chimeric transcripts are produced upon the coalescing of exons/introns from both sense and antisense transcripts ... -
Deep learning-based image analysis methods for the localization and classification of cancer cells in culture
(Universitat Politècnica de Catalunya, 2021-05-14)
Treball Final de Grau
Accés restringit per acord de confidencialitat -
Enhanced generation of reactive species by cold plasma in gelatin solutions for selective cancer cell death
(2020-10-06)
Article
Accés obert
Realitzat a/amb: GREMI Groupe de Recherches sur l’Energétique des Milieux IonisésAtmospheric pressure plasma jets generate reactive oxygen and nitrogen species (RONS) in liquids and biological media, which find application in the new area of plasma medicine. These plasma-treated liquids were demonstrated ... -
Experimental measurements and numerical analysis of volume changes in living cell after mechanical deformation
(Universitat Politècnica de Catalunya, 2021-07-02)
Treball Final de Grau
Accés obertLes forces mecàniques intervenen en el funcionament normal de les cèl·lules, tant en el funcionament vital dels òrgans, com el cor o els pulmons, o en el cas de les malalties, com quan una cèl·lula cancerosa migra i es ... -
Fabrication and characterization of hydrogels mimicking the tumor environment
(Universitat Politècnica de Catalunya, 2020-11-24)
Treball Final de Grau
Accés restringit per acord de confidencialitat -
FUS-CHOP promotes invasion in myxoid liposarcoma through a SRC/FAK/RHO/ROCK-dependent pathway
(2017-01-28)
Article
Accés obertDeregulated SRC/FAK signaling leads to enhanced migration and invasion in many types of tumors. In myxoid and round cell liposarcoma (MRCLS), an adipocytic tumor characterized by the expression of the fusion oncogene ... -
Loading of antibiotic into biocoated hydroxyapatite nanoparticles: smart antitumor platforms with regulated release
(American Chemical Society (ACS), 2018-07-26)
Article
Accés obertIn this research we propose a nanoplatform for anticancer therapy that is based on the combination of three components: (1) an antibiotic to target selectively the mitochondria of cancer cells, inhibiting their functions; ... -
Lymphoid chemockine secretion by B16 melanoma cancer cells and it effects on communication with lymphatics and the immune systhem
(Universitat Politècnica de Catalunya / École Polytechnique Fédérale de Lausanne, 2008)
Projecte/Treball Final de Carrera
Accés restringit per acord de confidencialitat -
Optimizing dosage-specific treatments in a multi-Scale model of a tumor growth
(Frontiers Media, 2022-04)
Article
Accés obertThe emergence of cell resistance in cancer treatment is a complex phenomenon that emerges from the interplay of processes that occur at different scales. For instance, molecular mechanisms and population-level dynamics ... -
PhysiBoSS 2.0: a sustainable integration of stochastic Boolean and agent-based modelling frameworks
(Nature Research, 2023)
Article
Accés obertIn systems biology, mathematical models and simulations play a crucial role in understanding complex biological systems. Different modelling frameworks are employed depending on the nature and scales of the system under ... -
Reconocimiento automático de células malignas en sangre periférica a partir de imágenes digitales y utilizando redes neuronales convolucionales
(Universitat Politècnica de Catalunya, 2018-06-28)
Treball Final de Grau
Accés obertExiste una gran variedad de patologías que afectan a los glóbulos blancos, desde enfermedades benignas a patologías graves. Las leucemias son patologías que se originan por proliferaciones incontroladas de los precursores ... -
SENTISIM: A hybrid training platform for SLNB in local melanoma staging
(Università degli Studi di Genova, 2019)
Text en actes de congrés
Accés obertSentinel Lymph Node Biopsy (SLNB) has been established as an accurate procedure for regional melanoma staging. SNLB has a diagnostic significance as biopsy-based staging identifies patients with nodal metastases who may ... -
Simulació de creixement cel·lular en tumors
(Universitat Politècnica de Catalunya, 2014-10-14)
Treball Final de Grau
Accés obertS'ha recollit informació sobre el comportament de les cèl·lules tumorals i dades estadístiques dels diferents paràmetres que defineixen el seu comportament. Degut al gran nombre de tipus com de subtipus de tumors, s'ha ... -
Solid-phase-assisted synthesis of targeting peptide-PEG-oligo(ethane amino)amides for receptor-mediated gene delivery
(2012)
Article
Accés obert
Realitzat a/amb: Technische Universität MünchenIn the forthcoming era of cancer gene therapy, efforts will be devoted to the development of new efficient and non-toxic gene delivery vectors. In this regard, the use of Fmoc/Boc-protected oligo(ethane amino)acids as ...