Exploració per autor "Weir, B.S."
Ara es mostren els items 1-6 de 6
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A genome-wide study of Hardy–Weinberg equilibrium with next generation sequence data
Graffelman, Jan; Jain, Deepti; Weir, B.S. (2017-04-03)
Article
Accés obertStatistical tests for Hardy–Weinberg equilibrium have been an important tool for detecting genotyping errors in the past, and remain important in the quality control of next generation sequence data. In this paper, we ... -
Exact inference for Hardy-Weinberg proportions with missing genotypes: single and multiple imputation
Graffelman, Jan; Nelson, S.; Gogarten, S.M.; Weir, B.S. (2015-09-15)
Article
Accés obertThis paper addresses the issue of exact-test based statistical inference for Hardy-Weinberg equilibrium in the presence of missing genotype data. Missing genotypes often are discarded when markers are tested for Hardy-Weinberg ... -
Multi-allelic exact tests for Hardy-Weinberg equilibrium that account for gender
Graffelman, Jan; Weir, B.S. (Wiley, 2018-01)
Article
Accés obertStatistical tests for Hardy–Weinberg equilibrium are important elementary tools in genetic data analysis. X-chromosomal variants have long been tested by applying autosomal test procedures to females only, and gender is ... -
On the testing of Hardy-Weinberg proportions and equality of allele frequencies in males and females at biallelic genetic markers
Graffelman, Jan; Weir, B.S. (2018-02-01)
Article
Accés obertStandard statistical tests for equality of allele frequencies in males and females and tests for Hardy-Weinberg equilibrium are tightly linked by their assumptions. Tests for equality of allele frequencies assume Hardy-Weinberg ... -
Testing for Hardy–Weinberg equilibrium at biallelic genetic markers on the X chromosome
Graffelman, Jan; Weir, B.S. (2016-04-13)
Article
Accés obertTesting genetic markers for Hardy–Weinberg equilibrium (HWE) is an important tool for detecting genotyping errors in large-scale genotyping studies. For markers at the X chromosome, typically the ¿2 or exact test is applied ... -
The transitivity of the Hardy-Weinberg law
Graffelman, Jan; Weir, B.S. (2022-05-01)
Article
Accés obertThe Hardy–Weinberg law is shown to be transitive in the sense that a multi-allelic polymorphism that is in equilibrium will retain its equilibrium status if any allele together with its corresponding genotypes is deleted ...