Now showing items 1-4 of 4

    • Binding of a C-end rule peptide to the neuropilin-1 receptor: a molecular modeling approach 

      Haspel, Nurit; Zanuy Gomara, David; Nussinov, Ruth; Teesalu, Tambet; Ruoslahti, Erkki; Alemán Llansó, Carlos (2011-03-15)
      Article
      Restricted access - publisher's policy
      Neuropilin-1 (NRP-1) is a receptor that plays an essential role in angiogenesis, vascular permeability, and nervous system development. Previous studies have shown that peptides with an N-terminal Arg, especially peptides ...
    • Journal of Structural Biology 

      Zanuy Gomara, David; Kotla, Rohith; Nussinov, Ruth; Teesalu, Tambet; Sugahara, Kazuki N.; Alemán Llansó, Carlos; Haspel, Nurit (2013-02-24)
      Article
      Restricted access - publisher's policy
      Neuropilin-1 (NRP-1) is a hub receptor that plays an essential role in angiogenesis and vascular perme- ability. It is over-expres sed in the new blood vessels grown by tumor cells and is a target for anti-tumor treatment ...
    • Phage-display-derived peptide binds to human CD206 and modeling reveals a new binding site on the receptor 

      Asciutto, Eliana K.; Kopanchuk, Sergei; Lepland, Anni; Simón Gracia, Lorena; Alemán Llansó, Carlos; Teesalu, Tambet; Scodeller, Pablo (American Chemical Society (ACS), 2019-03-07)
      Article
      Open Access
      We recently identified a tumor-homing peptide (mUNO, sequence: “CSPGAK”) that specifically interacts with mouse CD206 to target CD206/MRC1-expressing tumor-associated macrophages in mice. Here, we report studies on the ...
    • Sequence dependence of C-end rule peptides in binding and activation of > neuropilin-1 receptor 

      Zanuy Gomara, David; Kotla, Rohith; Nussinov, Ruth; Teesalu, Tambet; Sugahara, Kazuki N.; Alemán Llansó, Carlos; Haspel, Nurit (2013-05)
      Article
      Restricted access - publisher's policy
      Neuropilin-1 (NRP-1) is a hub receptor that plays an essential role in angiogenesis and vascular permeability. It is over-expressed in the new blood vessels grown by tumor cells and is a target for anti-tumor treatments. ...