Exploració per autor "Subirana, Juan Antonio"

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    • In and out of the minor groove: Interaction of an AT-rich DNA with the drug CD27 

      Acosta Reyes, Francisco Javier; Dardonville, Cristophe Y.; De Koning, Harry Pieter; Natto, Manal J.; Subirana, Juan Antonio; Campos López, Josefina de Lourdes (2014-06)
      Article
      Accés obert
      The DNA of several pathogens is very rich in AT base pairs. Typical examples include the malaria parasite Plasmodium falciparum and the causative agents of trichomoniasis and trypanosomiases. This fact has prompted studies ...

    • Structure of the DNA duplex d(ATTAAT)(2) with Hoogsteen hydrogen bonds 

      Acosta Reyes, Francisco Javier; Subirana, Juan Antonio; Campos López, Josefina de Lourdes; Alechaga, Elida (2015-03-17)
      Article
      Accés obert
      The traditional Watson-Crick base pairs in DNA may occasionally adopt a Hoogsteen conformation, with a different organization of hydrogen bonds. Previous crystal structures have shown that the Hoogsteen conformation is ...