Exploració per autor "Nicolai, Beatrice"
Ara es mostren els items 1-6 de 6
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An integrated view of theiInfluence of temperature, pressure, and humidity on the stability of trimorphic cysteamine hydrochloride
Gana, Inès; Barrio Casado, María del; Ghaddar, Carine; Nicolai, Beatrice; Do, Bernard; Tamarit Mur, José Luis; Safta, Fathi; Rietveld, Ivo B. (2015-07-01)
Article
Accés obertUnderstanding the phase behavior of pharmaceuticals is important for dosage form development and regulatory requirements, in particular after the incident with ritonavir. In the present paper, a comprehensive study of the ... -
Liquid-liquid miscibility gaps in drug-water binary systems: crystal Structure and thermodynamic properties of prilocaine and the temperature-composition phase diagram of the prilocaine-water system
Rietveld, Ivo B.; Perrin, Jean-Claude; Toscani, Siro; Barrio Casado, María del; Nicolai, Beatrice; Tamarit Mur, José Luis; Céolin, René (2013-04)
Article
Accés restringit per política de l'editorialEMLA cream, a “eutectic mixture of local anesthetics”, was developed in the early 1980s by Astra Pharmaceutical Production. The mixture of anesthetics containing lidocaine, prilocaine, and water is liquid at room ... -
On the polymorphism of l -citrulline: Crystal structure and characterization of the orthorhombic d form
Allouchi, Hassan; Nicolai, Beatrice; Barrio Casado, María del; Céolin, René; Mahé, Nathalie; Tamarit Mur, José Luis; Do, Bernard; Rietveld, Ivo B. (2014-03-01)
Article
Accés restringit per política de l'editorialSolid-state properties of active pharmaceutical compounds are closely related to their dissolution behavior and bioavailability, and understanding their phase behavior leads to better control in the drug formulation process. ... -
Solid-state properties and dehydration behavior of the active pharmaceutical ingredient potassium guaiacol-4-sulfonate
Mahé, Nathalie; Nicolai, Beatrice; Barrio Casado, María del; Perrin, Marc Antoine; Do, Bernard; Tamarit Mur, José Luis; Céolin, René; Rietveld, Ivo B. (2013-05-20)
Article
Accés restringit per política de l'editorialPotassium guaiacolsulfonate is an active pharmaceutical ingredient that has been in use for more than a century, and it is still widely used in cough syrups. Nonetheless, no crystal structure has ever been determined to ... -
Thermodynamics by synchrotron X-ray diffraction: phase relationships and crystal structure of L-tyrosine ethyl ester form III
Nicolai, Beatrice; Itie, Jean-Paul; Barrio Casado, María del; Tamarit Mur, José Luis; Rietveld, Ivo B. (2015-01-01)
Article
Accés obertIn the case of small organic molecules, phase behaviour, which is important for pharmaceutical applications, is often only studied as a function of temperature. However, for a full thermodynamic description, not only the ... -
Triethylenetetramine dihydrochloride: interactions and conformations in two anhydrous structures and a hydrate
Henriet, Theo; Nicolai, Beatrice; Ghaddar, Carine; Barrio Casado, María del; Do, Bernard; Yagoubi, Najet; Tamarit Mur, José Luis; Rietveld, Ivo B. (2015-01-01)
Article
Accés obertTriethylenetetramine is a polyamine type chelating ligand for copper(II), which is currently used, mainly in its dihydrochloride form, as an alternative to d-penicillamine against Wilsons disease. Because knowledge about ...