• Disassembling bacterial extracellular matrix with DNase-coated nanoparticles to enhance antibiotic delivery in biofilm infections 

      Baelo, Aida; Levato, Riccardo; Julian, Esther; Crespo, A.; Astola, Jose; Gavalda, Joan; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel; Torrents, Eduard (2015-07-10)
      Article
      Accés obert
      Realitzat a/amb:   Hospital Universitari Vall d'Hebron
      Infections caused by biofilm-forming bacteria are a major threat to hospitalized patients and the main cause of chronic obstructive pulmonary disease and cystic fibrosis. There is an urgent necessity for novel therapeutic ...
    • Injectable biodegradable carriers for the delivery of therapeutic agents and tissue engineering 

      Levato, Riccardo (Universitat Politècnica de Catalunya, 2015-01-09)
      Tesi
      Accés obert
      The design of smart biomaterial devices plays a key role to improve the way conventional therapies are being delivered, and to promote the development of new approaches for advanced therapies, such as regenerative medicine ...
    • Layer-by-layer bioassembly of cellularized polylactic acid porous 3 membranes for bone tissue engineering 

      Guduric, Vera; Metz, Carole; Robin, Siadous; Bareille, Reine; Levato, Riccardo; Engel López, Elisabeth; Fricain, Jean-Christophe; Devillard, Raphaël; Luzanin, Ognjan; Catros, Sylvain (Springer, 2017-03-22)
      Article
      Accés obert
      The conventional tissue engineering is based on seeding of macroporous scaffold on its surface (“top–down” approach). The main limitation is poor cell viability in the middle of the scaffold due to poor diffusion of oxygen ...
    • Modular bioink for 3D printing of biocompatible hydrogels: sol-gel polymerization of hybrid peptides and polymers 

      Echalier, Cecile; Levato, Riccardo; Mateos Timoneda, Miguel Ángel; Castaño Linares, Óscar; Dejean, S; Garric, X; Pinese, C; Noël, D; Engel López, Elisabeth; Martinez, J; Mehdi, A; Subra, Gilles (Royal Society of Chemistry, 2017-02-21)
      Article
      Accés obert
      An unprecedented generic system allowing the 3D printing of peptide-functionalized hydrogels by soft sol–gel inorganic polymerization is presented. Hybrid silylated inorganic/bioorganic blocks are mixed in biological buffer ...
    • Polylactic acid organogel as versatile scaffolding technique 

      Punet, Xavier; Levato, Riccardo; Bataille, Isabelle; Letourneur, Didier; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel (Elsevier, 2017-03-24)
      Article
      Accés obert
      Tissue engineering requires scaffolding techniques based on non-toxic processes that permits the fabrication of constructs with tailored properties. Here, a two-step methodology based on the gelation and precipitation of ...
    • Role of ECM/peptide coatings on SDF-1a triggered mesenchymal stromal cell migration from microcarriers for cell therapy 

      Levato, Riccardo; Planell Estany, Josep Anton; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth (2015-05-01)
      Article
      Accés obert
      Many cell therapies rely on the ability of mesenchymal stromal cells (MSCs) to diffuse and localize throughout the target tissue-such as tumoral and ischemic tissues-, in response to specific cytokine signals, rather than ...