Now showing items 41-60 of 68

    • Layer-by-layer bioassembly of cellularized polylactic acid porous 3 membranes for bone tissue engineering 

      Guduric, Vera; Metz, Carole; Robin, Siadous; Bareille, Reine; Levato, Riccardo; Engel López, Elisabeth; Fricain, Jean-Christophe; Devillard, Raphaël; Luzanin, Ognjan; Catros, Sylvain (Springer, 2017-03-22)
      Article
      Open Access
      The conventional tissue engineering is based on seeding of macroporous scaffold on its surface (“top–down” approach). The main limitation is poor cell viability in the middle of the scaffold due to poor diffusion of oxygen ...
    • Layer-by-layer modification effects on a nanopore's inner surface of polycarbonate track-etched membranes 

      Paoli, Roberto; Engel López, Elisabeth; Homs-Corbera, A; Samitier Martí, Josep (Royal Society of Chemistry (RSC), 2020)
      Article
      Open Access
      The control of the morphology, as well as the physical and chemical properties, of nanopores is a key issue for many applications. Reducing pore size is important in nanopore-based sensing applications as it helps to ...
    • Modular bioink for 3D printing of biocompatible hydrogels: sol-gel polymerization of hybrid peptides and polymers 

      Echalier, Cecile; Levato, Riccardo; Mateos Timoneda, Miguel Ángel; Castaño Linares, Óscar; Dejean, S; Garric, X; Pinese, C; Noël, D; Engel López, Elisabeth; Martinez, J; Mehdi, A; Subra, Gilles (Royal Society of Chemistry, 2017-02-21)
      Article
      Open Access
      An unprecedented generic system allowing the 3D printing of peptide-functionalized hydrogels by soft sol–gel inorganic polymerization is presented. Hybrid silylated inorganic/bioorganic blocks are mixed in biological buffer ...
    • Modular polylactic acid microparticle-based scaffolds prepared via microfluidic emulsion/solvent displacement process: Fabrication, characterization, and in vitro mesenchymal stem cells interaction study 

      Salerno, Aurelio; Levato, R.; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth; Netti, Paolo Antonio; Planell Estany, Josep Anton (2012-08-31)
      Article
      Restricted access - publisher's policy
      The present study reports a novel approach for the design and fabrication of polylactic acid (PLA) microparticle- based scaffolds with microstructural properties suitable for bone and cartilage regeneration. Macroporous ...
    • Nanotechnology approaches in chronic wound healing 

      Blanco Fernández, Bárbara; Castaño, Óscar; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth; Pérez Amodio, Soledad Graciela (2020-06-02)
      Article
      Restricted access - publisher's policy
      Significance: The incidence of chronic wounds is increasing due to our aging population and the augment of people afflicted with diabetes. With the extended knowledge on the biological mechanisms underlying these diseases, ...
    • Nanotechnology in regenerative medicine: the materials side 

      Engel López, Elisabeth; Michiardi, A; Navarro, M; Lacroix, Damien Jerome; Planell Estany, Josep Anton (2008-01)
      Article
      Open Access
      Regenerative medicine is an emerging multidisciplinary field that aims to restore, maintain or enhance tissues and hence organ functions. Regeneration of tissues can be achieved by the combination of living cells, which ...
    • Neurogenesis and vascularization of the damaged brain using a lactate-releasing biomimetic scaffold 

      Álvarez Pinto, Zaída; Castaño Linares, Óscar; Castells, Alba; Mateos Timoneda, Miguel Ángel; Planell Estany, Josep Anton; Engel López, Elisabeth; Alcántara, Soledad (2014-06)
      Article
      Restricted access - publisher's policy
      Regenerative medicine strategies to promote recovery following traumatic brain injuries are currently focused on the use of biomaterials as delivery systems for cells or bioactive molecules. This study shows that cell-free ...
    • Optimization of blend parameters for the fabrication of polycaprolactone-silicon based ormoglass nanofibers by electrospinning 

      Sachot, Nadège; Castaño Linares, Óscar; Planell Estany, Josep Anton; Engel López, Elisabeth (2015-08-01)
      Article
      Open Access
      Electrospinning is a method that can be used to efficiently produce scaffolds that mimic the fibrous structure of natural tissue, such as muscle structures or the extracellular matrix of bone. The technique is often used ...
    • Osteoblast-like cellular response to dynamic changes in the ionic extracellular environment produced by calcium-deficient hydroxyapatite 

      Gustavsson, Johan; Ginebra Molins, Maria Pau; Planell Estany, Josep Anton; Engel López, Elisabeth (2012-10)
      Article
      Restricted access - publisher's policy
      Solution-mediated reactions due to ionic substitutions are increasingly explored as a strategy to improve the biological performance of calcium phosphate-based materials. Yet, cellular response to well-defined ...
    • Oxidación superficial de aleaciones de NiTi para la mejora de la biocompatibilidad 

      Michiardi, Alexandra; Engel López, Elisabeth; Planell Estany, Josep Anton; Gil Mur, Francisco Javier (Sociedad Ibérica de Biomecánica y Biomateriales, 2004-12)
      Article
      Open Access
      Se han estudiado diferentes tratamientos superficiales con el fin de obtener una capa de TiO2 con una mínima concentración de Ni en la superficie de aleaciones de NiTi 50/50 con memoria de forma: pulido espejo, autoclave, ...
    • PEG hydrogel containing calcium-releasing particles and mesenchymal stromal cells promote vessel maturation 

      Navarro Requena, Claudia; Weaver, Jessica D.; Clark, Amy Y.; Clift, Douglas; Pérez Amodio, Soledad Graciela; Castaño Linares, Óscar; Zhou, Dennis W.; García, Andrés J.; Engel López, Elisabeth (2018-02)
      Article
      Restricted access - publisher's policy
      The use of human mesenchymal stromal cells (hMSC) for treating diseased tissues with poor vascularization has received significant attention, but low cell survival has hampered its translation to the clinic. Bioglasses and ...
    • Perfusion cell seeding on large porous PLA/calcium phosphate composite scaffolds in a perfusion bioreactor system under varying perfusion parameters. 

      Koch, M.A.; Vrij, E.J.; Engel López, Elisabeth; Planell Estany, Josep Anton; Lacroix, Damien Jerome (2010-12-17)
      Article
      Restricted access - publisher's policy
      A promising approach to bone tissue engineering lies in the use of perfusion bioreactors where cells are seeded and cultured on scaffolds under conditions of enhanced nutrient supply and removal of metabolic products. ...
    • Poly-L/DL-lactic acid films functionalized with collagen IV as carrier substrata for corneal epithelial stem cells 

      de la Mata Sampedro, Ana; Mateos Timoneda, Miguel Ángel; Nieto Miguel, Teresa; Galindo de la Rosa, Sara; López Paniagua, Marina; Planell Estany, Josep Anton; Engel López, Elisabeth; Calonge Cano, Margarita (2019-05-01)
      Article
      Restricted access - publisher's policy
      Limbal epithelial stem cells (LESCs) are responsible for the renewal of corneal epithelium. Cultivated limbal epithelial transplantation is the current treatment of choice for restoring the loss or dysfunction of LESCs. ...
    • Polylactic acid organogel as versatile scaffolding technique 

      Punet, Xavier; Levato, Riccardo; Bataille, Isabelle; Letourneur, Didier; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel (Elsevier, 2017-03-24)
      Article
      Open Access
      Tissue engineering requires scaffolding techniques based on non-toxic processes that permits the fabrication of constructs with tailored properties. Here, a two-step methodology based on the gelation and precipitation of ...
    • Polymeric composite dressings containing calcium-releasing nanoparticles accelerate wound healing in diabetic mice 

      Pérez Amodio, Soledad Graciela; Rubio, Nuria; Vila, Olaia; Navarro Requena, Claudia; Castaño, Óscar; Sanchez Ferrero, Aitor; Martí Muñoz, Joan; Alsina Gibert, Merce; Blanco Fernández, Jerónimo; Engel López, Elisabeth (2020-08-07)
      Article
      Restricted access - publisher's policy
      Objective: Wound healing is a complex process that involves the interaction between different cell types and bioactive factors. Impaired wound healing is characterized by a loss in synchronization of these interactions, ...
    • Polymers for bone repair 

      Rey Viñoles, Sergi; Engel López, Elisabeth; Mateos Timoneda, Miguel Ángel (Woodhead Publishing, 2019-01-11)
      Part of book or chapter of book
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      The substitution of tissues due to tumors, pathologies, or traumatic accidents is well known, and different surgical branches perform these kinds of surgeries on a daily basis with relative ease. The substitution of bone ...
    • Real-time bioluminescence imaging of cell distribution, growth, and differentiation in a three-dimensional scaffold under interstitial perfusion for tissue engineering 

      Vila, Olaia; Garrido, Cristina; Guerra Rebollo, Marta; Navarro Toro, Melba; Meca-Cortes, O; Mas, S; Engel López, Elisabeth; Rubio, Nuria; Blanco, Jeronimo (2016-09-01)
      Article
      Restricted access - publisher's policy
      Bioreactor systems allow safe and reproducible production of tissue constructs and functional analysis of cell behavior in biomaterials. However, current procedures for the analysis of tissue generated in biomaterials ...
    • Relevance of PEG in PLA-based blends for tissue engineering 3D-printed scaffolds 

      Serra, Tiziano; Ortiz Hernández, Mónica; Engel López, Elisabeth; Planell Estany, Josep Anton; Navarro Toro, Melba Eugenia (2014-05-01)
      Article
      Restricted access - publisher's policy
      Achieving high quality 3D-printed structures requires establishing the right printing conditions. Finding processing conditions that satisfy both the fabrication process and the final required scaffold properties is crucial. ...
    • Role of ECM/peptide coatings on SDF-1a triggered mesenchymal stromal cell migration from microcarriers for cell therapy 

      Levato, Riccardo; Planell Estany, Josep Anton; Mateos Timoneda, Miguel Ángel; Engel López, Elisabeth (2015-05-01)
      Article
      Open Access
      Many cell therapies rely on the ability of mesenchymal stromal cells (MSCs) to diffuse and localize throughout the target tissue-such as tumoral and ischemic tissues-, in response to specific cytokine signals, rather than ...
    • Streptococcus sanguinis adhesion on titanium rough surfaces: effect of shot blasting particles 

      Rodríguez Hernández, Ana Guadalupe; Juárez, A.; Engel López, Elisabeth; Gil Mur, Francisco Javier (Springer, 2011)
      Article
      Restricted access - publisher's policy
      Dental implant failure is commonly associated to dental plaque formation. This problem starts with bacterial colonization on implant surface upon implantation. Early colonizers (such as Streptococcus sanguinis) play ...