Exploració per tema "Enzims"
Ara es mostren els items 21-40 de 48
-
Isohexide and sorbitol-derived, enzymatically synthesized renewable polyesters with enhanced Tg
(2016-10-10)
Article
Accés obertSugar-based polyesters derived from sorbitol and isohexides were obtained via solvent-free enzymatic catalysis. Pendant hydroxyl groups, coming from the sorbitol units, were present along the polyester backbone, whereas ... -
Known evolutionary paths are accessible to engineered ß-Lactamases having altered protein motions at the timescale of catalytic turnover
(Frontiers, 2020)
Article
Accés obertThe evolution of new protein functions is dependent upon inherent biophysical features of proteins. Whereas, it has been shown that changes in protein dynamics can occur in the course of directed molecular evolution ... -
Laccase from Pycnoporus cinnabarinus and phenolic compounds: can the efficiency of an enzyme mediator for delignifying kenaf pulp be predicted?
(2012-03)
Article
Accés restringit per política de l'editorialIn this work, kenaf pulp was delignified by using laccase in combination with various redox mediators and the efficiency of the different laccase–mediator systems assessed in terms of the changes in pulp properties after ... -
Mapping enzyme-substrate interactions: its potential to study the mechanism of enzymes
(Academic Press Inc., 2020-09)
Capítol de llibre
Accés obertWith the increase of the need to use more sustainable processes for the industry in our society, the modeling of enzymes has become crucial to fully comprehend their mechanism of action and use this knowledge to enhance ... -
Mapping the Long-Range Electron Transfer Route in Ligninolytic Peroxidases
(ACS Publications, 2017-04-04)
Article
Accés obertCombining a computational analysis with site-directed mutagenesis, we have studied the long-range electron transfer pathway in versatile and lignin peroxidases, two enzymes of biotechnological interest that play a key role ... -
Mechanistic insights into the reaction of chlorination of tryptophan catalyzed by tryptophan 7-halogenase
(Macmillan Publishers, 2017-12-12)
Article
Accés obertTryptophan 7-halogenase catalyzes chlorination of free tryptophan to 7-chlorotryptophan, which is the first step in the antibiotic pyrrolnitrin biosynthesis. Many biologically and pharmaceutically active natural products ... -
Metagenomic mining for esterases in the microbial community of Los Rueldos acid mine drainage formation
(Frontiers Media, 2022-05)
Article
Accés obertAcid mine drainage (AMD) systems are extremely acidic and are metal-rich formations inhabited by relatively low-complexity communities of acidophiles whose enzymes remain mostly uncharacterized. Indeed, enzymes from only ... -
Modelización de la acción de una proteasa en las características físicas de un tejido de lana
(Instituto de Investigación Textil y Cooperación Industrial, 2004-01)
Article
Accés obertSe estudia la acción de proteasas en una serie de propiedades físicas de tejidos de calada, considerando la aplicación de este tipo de enzimas en el acabado textil. Se estudia la influencia de la concentración de enzima, ... -
Molecular Modeling in Enzyme Design, Toward In Silico Guided Directed Evolution
(Springer, 2017-02-15)
Capítol de llibre
Accés obertDirected evolution (DE) creates diversity in subsequent rounds of mutagenesis in the quest of increased protein stability, substrate binding, and catalysis. Although this technique does not require any structural/mechanistic ... -
Multiple implications of an active site phenylalanine in the catalysis of aryl-alcohol oxidase
(Nature Publishing Group, 2018-05-25)
Article
Accés obertAryl-alcohol oxidase (AAO) has demonstrated to be an enzyme with a bright future ahead due to its biotechnological potential in deracemisation of chiral compounds, production of bioplastic precursors and other reactions ... -
Nano-engineering stable contact-based antimicrobials: Chemistry at the interface between nano-gold and bacteria
(Elsevier, 2021-12)
Article
Accés obertContact-based antimicrobials, as antibiotic-free technologies that use non-specific interactions with bacterial cells to exert antimicrobial activity, are a prospective solution in fighting the global issue of bacterial ... -
Obtenció de nanocel·lulosa utilitzant enzims
(Universitat Politècnica de Catalunya, 2016-04-26)
Treball Final de Grau
Accés obertEls nanocristalls de cel·lulosa (NCC) tenen unes propietats físico-mecàniques i de biocompatibilitat que es poden aplicar als camps de biomedicina, electrònica i farmacèutica. Els NCC s’obtenen a partir d’una hidròlisis ... -
Oxidoreductases on their way to industrial biotransformations
(Elsevier, 2017-11)
Article
Accés obertFungi produce heme-containing peroxidases and peroxygenases, flavin-containing oxidases and dehydrogenases, and different copper-containing oxidoreductases involved in the biodegradation of lignin and other recalcitrant ... -
PluriZymes: new enzymes for new times
(Barcelona Supercomputing Center, 2019-05-07)
Text en actes de congrés
Accés obert -
Probing the Surface of a Laccase for Clues towards the Design of Chemo-Enzymatic Catalysts
(Wiley, 2017-04)
Article
Accés obertSystems featuring a multi-copper oxidase associated with transition-metal complexes can be used to perform oxidation reactions in mild conditions. Here, a strategy is presented for achieving a controlled orientation of a ... -
Protein modelling for enzyme engineering
(Barcelona Supercomputing Center, 2017-05-04)
Text en actes de congrés
Accés obert -
Rational engineering of AA5_2 copper radical oxidases to probe the molecular determinants governing their substrate selectivity
(Wiley, 2023)
Article
Accés obertFungal copper radical oxidases (CROs) from the Auxiliary Activity family 5 (AA5) constitute a group of metalloenzymes that oxidize a wide panel of natural compounds, such as galactose-containing saccharides or primary ... -
Rational Engineering of Multiple Active Sites in an Ester Hydrolase
(American Chemical Society, 2018-03-30)
Article
Accés obertEffects of altering the properties of an active site in an enzymatic homogeneous catalyst have been extensively reported. However, the possibility of increasing the number of such sites, as commonly done in heterogeneous ... -
Rational Enzyme Engineering Through Biophysical and Biochemical Modeling
(ACS Publications, 2016-02-03)
Article
Accés obertDue to its importance in the pharmaceutical industry, ligand dynamic simulations have experienced a great expansion. Using all-atom models and cutting edge hardware, one can perform non-biased ligand migration, active site ... -
Repurposing designed mutants: a valuable strategy for computer-aided laccase engineering – the case of POXA1b
(Royal Society of Chemistry, 2017-01-04)
Article
Accés obertThe broad specificity of laccases, a direct consequence of their shallow binding site, makes this class of enzymes a suitable template to build specificity toward putative substrates. In this work, a computational methodology ...