Exploració per tema "Biomathematics"
Ara es mostren els items 21-40 de 163
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A system for phenotype harmonization in the National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) program
(2021-10-01)
Article
Accés obertGenotype-phenotype association studies often combine phenotype data from multiple studies to increase statistical power. Harmonization of the data usually requires substantial effort due to heterogeneity in phenotype ... -
A systematic review describes models for recruitment prediction at the design stage of a clinical trial
(2019-11-01)
Article
Accés obertPatient recruitment in clinical trials is challenging with failure to recruit to time and target sample size common. This may be caused by unanticipated problems or by overestimation of the recruitment rate. This study is ... -
A theory of ordering of elongated and curved proteins on membranes driven by density and curvature
(2021-02-02)
Article
Accés obertCell membranes interact with a myriad of curvature-active proteins that control membrane morphology and are responsible for mechanosensation and mechanotransduction. Some of these proteins, such as those containing BAR ... -
Adherence to reporting guidelines increases the number of citations: the argument for including a methodologist in the editorial process and peer-review
(2019-05-31)
Article
Accés obertFrom 2005 to 2010, we conducted 2 randomized studies on a journal (Medicina Clínica), where we took manuscripts received for publication and randomly assigned them to either the standard editorial process or to additional ... -
Advanced mathematics for new therapeutics: a proposal for chronic pain
(Universitat Politècnica de Catalunya, 2022-10)
Projecte Final de Màster Oficial
Accés obertG protein-coupled receptors are membrane proteins that transmit signals inside the cell by the interaction of neurotransmitters, hormones, and synthetic molecules. These proteins may be present in the membrane forming ... -
Algebraic invariants of phylogenetic networks
(Universitat Politècnica de Catalunya, 2023-05-02)
Projecte Final de Màster Oficial
Accés obertPhylogenetics is a scientific field that focuses on understanding the evolutionary relationships between living organisms. Specifically, it seeks to reconstruct the evolutionary history of these organisms and the ... -
Algebraic statistics in phylogenetic reconstruction: incorporating invariable sites
(Universitat Politècnica de Catalunya, 2023-06)
Projecte Final de Màster Oficial
Accés obertIn modern phylogenetics, when comparing sequences of DNA the traditional approach assumes that nu- cleotide substitutions follow a Markov model, that sites on a DNA sequence evolve independently and in the same way. However, ... -
An iterative method to protect the type I error rate in bioequivalence studies under two-stage adaptive 2×2 crossover designs
(2021-01)
Article
Accés obertBioequivalence studies are the pivotal clinical trials submitted to regulatory agen- cies to support the marketing applications of generic drug products. Average bioequivalence (ABE) is used to determine whether the mean ... -
Analysis of miRNA-mRNA interactions in alcoholic hepatitis
(Universitat Politècnica de Catalunya, 2014-01)
Projecte Final de Màster Oficial
Accés restringit per decisió de l'autorThis project is dedicated to the search of miRNA factors that possibly modify the expression of genes related to alcoholic hepatitis. Expression has been measured for a large number of genes and miRNAs in a database of 12 ... -
Analysis of self-overlap reveals trade-offs in plankton swimming trajectories
(2014-07-06)
Article
Accés restringit per política de l'editorialMovement is a fundamental behaviour of organisms that not only brings about beneficial encounters with resources and mates, but also at the same time exposes the organism to dangerous encounters with predators. The movement ... -
Anàlisi i desenvolupament de models matemàtics per a ritmes del son
(Universitat Politècnica de Catalunya, 2018-05)
Treball Final de Grau
Accés obertEl camp de la neurociència estudia el comportament i l'activitat del sistema nerviós, en particular les regions del cervell implicades en la regulació del son. En aquest projecte es considera un model matemàtic per al cicle ... -
Anisotropic microsphere-based approach to damage in soft fibered tissue
(2012-05)
Article
Accés obertAn anisotropic damage model for soft fibered tissue is presented in this paper, using a multi-scale scheme and focusing on the directionally dependent behavior of these materials. For this purpose, a micro-structural or, ... -
Ankle sprain versus muscle strain injury in professional men's basketball: a 9-year prospective follow-up study
(2019-06-11)
Article
Accés obert -
Any internacional de la biologia matemàtica: guia de lectura
(2018-10-29)
Guia temàtica
Accés obert -
Application of algebraic techniques to phylogenetic reconstruction
(Universitat Politècnica de Catalunya, 2015-05)
Treball Final de Grau
Accés obertPhylogenetics is the study of the evolutionary relationships among different species through the analysis of sequences of biological data such as DNA. These relationships are usually represented using phylogenetic trees, ... -
APRIL: a double-blind, placebo-controlled, randomized, Phase Ib/IIa clinical study of ApTOLL for the treatment of acute ischemic stroke
(Frontiers Media SA, 2023-02-24)
Article
Accés obertIn the reperfusion era, a new paradigm of treating patients with endovascular treatment (EVT) and neuroprotective drugs is emerging as a promising therapeutic option for patients with acute ischemic stroke (AIS). In this ... -
Avaluació de procediments d’estimació en models de mescla per a isòtops estables
(Universitat Politècnica de Catalunya, 2013-02)
Projecte Final de Màster Oficial
Accés restringit per decisió de l'autorEn l’àmbit de l'ecologia, els isòtops estables constitueixen un eina molt valuosa per a reconstruir la dieta, ja que a partir de les signatures isotòpiques d’una mostra de consumidors i de les signatures isotòpiques de les ... -
Biological convergence of cancer signatures
(2009-09-18)
Article
Accés obertGene expression profiling has identified cancer prognostic and predictive signatures with superior performance to conventional histopathological or clinical parameters. Consequently, signatures are being incorporated into ... -
Biomedical applications of bacterial inclusion bodies
(John Wiley & Sons, Inc., 2014-08)
Capítol de llibre
Accés obert -
Boosting the chances to imporve stroke treatment
(2009-12-24)
Article
Accés obertBackground and Purpose— There is a lack of agreement regarding measuring the effects of stroke treatment in clinical trials, which often relies on the dichotomized value of 1 outcome scale. Alternative analyses consist ...