Now showing items 21-40 of 71

    • Effectiveness of a new one-hour blood pressure monitoring method to diagnose hypertension: a diagnostic accuracy clinical trial protocol 

      González de Paz, Luis; Kostov, Belchin Adriyanov; Alvira Balada, Maria del Carme; Colungo, Cristina (2019-05-01)
      Article
      Open Access
      Introduction 24-hour ambulatory blood pressure monitoring (ABPM) is the gold standard diagnostic method for hypertension, but has some shortcomings in clinical practice while clinical settings often lack sufficient devices ...
    • Eigenanalysis analysis and metric multidimensional scaling on hierarchical structures 

      Cuadras, C.M. (Carlos Maria); Oller Sala, Josep Maria (Universitat Politècnica de Barcelona. Centre de Càlcul, 1987)
      Article
      Open Access
      The known hierarchical clustering scheme is equivalent to the concept of ul- trametric distance. AII distance can be represented in a spatial model using multidimensional scaling. We relate both clases of representations ...
    • El modelo evolutivo de Kimura, un enlace entre el álgebra, la biología i la estadística 

      Casanellas Rius, Marta (Real Sociedad Matemática Española, 2018-06-01)
      Article
      Open Access
      El álgebra y la estadística han estado presentes en biología evo- lutiva desde sus inicios. En este artículo mostramos una pequeña parte de la interrelación entre el álgebra, la estadística y la biología evolutiva centrándonos ...
    • Estimation of synaptic conductances using control theory 

      Tresserras Pujadas, Lluc (Universitat Politècnica de Catalunya, 2020-10)
      Master thesis
      Open Access
      Unveiling the input a neuron receives and distinguishing between excitation and inhibition provides information on local connectivity and brain operating conditions. However, experimental techniques do not allow direct ...
    • Estudi de fiabilitat i validació d’un score per avaluar la bronquiolitis en nens 

      Fabre Mitjans, Noëlle (Universitat Politècnica de Catalunya, 2014-06)
      Master thesis
      Restricted access - author's decision
      Actualment no existeix un gold estàndard per valorar el pronòstic ni la gravetat de la bronquiolitis, tot hi que resultaria molt útil per optimitzar l assistència clínica. En el present treball es va avaluar si l score ...
    • Force transduction and lipid binding in MscL: a continuum-molecular approach 

      Vanegas, Juan Manuel; Arroyo Balaguer, Marino (2014-12-01)
      Article
      Open Access
      The bacterial mechanosensitive channel MscL, a small protein mainly activated by membrane tension, is a central model system to study the transduction of mechanical stimuli into chemical signals. Mutagenic studies suggest ...
    • Front propagation speeds of T7 virus mutants 

      López de Rioja, Víctor; Fort, J.; Isern, N. (2015-11)
      Article
      Open Access
      We propose a new reaction-diffusion model with an eclipse time to study the spread of viruses on bacterial populations. This new model is both biologically and physically sound, unlike previous ones. We determine important ...
    • Hybrid cell-centred/vertex model for multicellular systems with equilibrium-preserving remodelling 

      Mosaffa, Payman; Rodríguez Ferran, Antonio; Muñoz Romero, José (John Wiley & sons, 2018-03)
      Article
      Open Access
      We present a hybrid vertex/cell-centred model for mechanically simulating planar cellular monolayers undergoing cell reorganisation. Cell centres are represented by a triangular nodal network, while the cell boundaries are ...
    • Hypergravity induces changes in physiology, gene expression and epigenetics in zebrafish 

      Salazar Moscoso, Marcela; Joly Ruiz Castellanos, Silvia; Anglada Escudé, Guillem; Ribas Cabezas, Laia (Universitat Politècnica de Catalunya, 2022-04-29)
      Conference lecture
      Open Access
      All living organisms that inhabit Earth have evolved under a common value of gravity, which amounts to an acceleration of 9.81 m/s2 at mean sea level. Changes on it could cause important alterations that affect vital ...
    • Impacto del bilingüismo en el rendimiento cognitivo y en la estructura cerebral de personas sanas a riesgo de padecer la enfermedad de Alzheimer 

      Cuadros Ramos, Anna (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2018-06)
      Master thesis
      Restricted access - author's decision
      Covenantee:   Btech Technical Center
      Uno de cada tres casos de enfermedad de Alzheimer (EA) es atribuible a factores que son modificables y, en consecuencia, potencialmente evitables. Adicionalmente existen una serie de variables asociadas con la formación ...
    • Inverting angiogenesis with interstitial flow and chemokine matrix-binding affinity 

      Moure, Adrian; Vilanova Caicoya, Guillermo; Gomez, Hector (Nature, 2022-05-10)
      Article
      Open Access
      The molecular signaling pathways that orchestrate angiogenesis have been widely studied, but the role of biophysical cues has received less attention. Interstitial flow is unavoidable in vivo, and has been shown to ...
    • La investigació ambiental dels brots de legionel·losi a l'Hospitalet de Llobregat en el període 2016-21 

      Caralt Pérez, Clara de (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2022-06)
      Master thesis
      Open Access
      Covenantee:   Universitat de Barcelona
      La legionel·losi és una malaltia produïda per un bacteri anomenat legionel·la que es contrau en inhalar vapor o aerosols d'aigua contaminada. Actualment és un problema de salut pública sobretot, per la seva presentació en ...
    • Lung cancer immunophenotyping with CT- radiomics 

      Zubieta Martin, Iker (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2022-06)
      Master thesis
      Open Access
      Covenantee:   Vall d'Hebron Institut d’Oncologia
      This master thesis has two aims. The first main objective is to study and obtain robust voxel-wise (3D) radiomic features for lung cancer and with them compute the habitats (unsupervised clusters) to unravel tumor heterogeneity ...
    • Machine learning for cancer classification 

      García Ortegón, Miguel (Universitat Politècnica de Catalunya, 2018-10)
      Master thesis
      Restricted access - author's decision
      Covenantee:   Centre de Regulació Genòmica. Departament de Teoria del Senyal i Comunicacions
      In this thesis, we used support vector machines (SVMs) to build a tissue-of-origin classifier of 17 cancer types. Our classifier, which uses RNA expression data from over 20000 genes, works with high accuracy on primary ...
    • Macroscopic limit of a kinetic model describing the switch in T cell migration modes via binary interactions 

      Estrada Rodríguez, Gissell; Lorenzi, Tommaso (2021-12-23)
      Article
      Open Access
      Experimental results on the immune response to cancer indicate that activation of cytotoxic T lymphocytes (CTLs) through interactions with dendritic cells (DCs) can trigger a change in CTL migration patterns. In particular, ...
    • Mathematical modeling of calcium handling dysfunctions leading to atrial fibrillation 

      Krizanec, Nikolina (Universitat Politècnica de Catalunya, 2017-10)
      Master thesis
      Open Access
      The aim of this master s thesis is to study the basic cardiac cellular electrophysiology in order to understand and examine the role of SK3 channels. Among the many channels present in an atrial myocyte, SK3 channels are ...
    • Maximum-likelihood estimation of the geometric niche preemption model 

      Graffelman, Jan (2021-12)
      Article
      Open Access
      The geometric series or niche preemption model is an elementary ecological model in biodiversity studies. The preemption parameter of this model is usually estimated by regression or iteratively by using May’s equation. ...
    • Mechanotransmission of haemodynamic forces by the endothelial glycocalyx in a full-scale arterial model 

      Sáez Viñas, Pablo; Gallo, Diego; Morbiducci, Umberto (2019-06-05)
      Article
      Open Access
      The glycocalyx has been identified as a key mechano-sensor of the shear forces exerted by streaming blood onto the vascular endothelial lining. Although the biochemical reaction to the blood flow has been extensively ...
    • Mining the integrated connectedness of biomedical systems 

      Przulj, Natasa (Barcelona Supercomputing Center, 2018)
      Conference report
      Open Access
    • Modeling and analysis of longitudinal data in clinical trials. Code of analysis implemented in R 

      Sánchez Martínez, Néstor (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2018-10)
      Master thesis
      Restricted access - author's decision
      En este trabajo hemos analizado un estudio de cohorte de pacientes de VIH, se ha realizado todo el proceso de gestión de datos y estadístico necesario. Se han realizado análisis descriptivos, análisis de supervivencia y ...