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Browsing by Author "Ivanova, Kristina Dimitrova"
Now showing items 21-40 of 44
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Layer-by-Layer coating of aminocellulose and quorum quenching acylase on silver nanoparticles synergistically eradicate bacteria and their biofilms
(2020-04-24)
Article
Open AccessThe emergence of antibiotic-resistant bacteria and the failure of the existing antibacterial therapeutics call for development of novel treatment strategies. Furthermore, the formation of bacterial biofilms restricts drug ... -
Layer-by-layer decorated nanoparticles with tunable antibacterial and antibiofilm properties against both gram-positive and gram-negative bacteria
(2018-01-09)
Article
Open Accessacteria-mediated diseases are a global healthcare concern due to the development and spread of antibiotic resistant strains. Cationic compounds are considered membrane active biocidal agents having a great potential to ... -
Multifunctional piezoelectric surfaces enhanced with layer-by-layer coating for improved osseointegration and antibacterial performance
(Elsevier, 2024-11)
Article
Open AccessImplant failure is primarily caused by poor osseointegration and bacterial colonization, which demands readmissions and revision surgeries to correct it. A novel approach involves engineering multifunctional interfaces ... -
Multifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort
(2019-02-13)
Article
Open AccessContact lenses (CL) provide visual correction but their use may also induce several adverse effects causative of discomfort and conditions that lead to stop or discontinue their use. Discomfort is mainly caused by insufficient ... -
Multimodal silver-chitosan-acylase nanoparticles inhibit bacterial growth and biofilm formation by gram-negative pseudomonas aeruginosa bacterium
(2023-05)
Article
Open AccessPseudomonas aeruginosa bacteria originate severe infections in hospitalized patients and those with chronic debilitating diseases leading to increased morbidity and mortality, longer hospitalization and huge financial ... -
Mussel-inspired sonochemical nanocomposite coating on catheters for prevention of urinary infections
(2024-06-25)
Article
Open AccessCatheter-associated urinary tract infections are the most common hospital-acquired infections and cause patient discomfort, increased morbidity, and prolonged stays, altogether posing a huge burden on healthcare services. ... -
Nano-engineering of a thermoplastic compound with CuO nanoparticles for the development of safe antimicrobial and anti-biofouling fish cage nets
(Royal Society of Chemistry (RSC), 2025-06-20)
Article
Open AccessThe occurrence of biofouling is the most common problem that may arise on the surface of sh cage nets in freshwater and the marine environment. The issue not only induces structural damage to the netting because of the ... -
Nano-formulation endows quorum quenching enzyme-antibiotic hybrids with improved antibacterial and antibiofilm activities against pseudomonas aeruginosa
(2022-07-11)
Article
Open AccessThe emergence of antibiotic resistant bacteria coupled with the shortage of efficient antibacterials is one of the most serious unresolved problems for modern medicine. In this study, the nano-hybridization of the clinically ... -
Nanomaterials and coatings for managing antibiotic-resistant biofilms
(2023-02-02)
Article
Open AccessBiofilms are a global health concern responsible for 65 to 80% of the total number of acute and persistent nosocomial infections, which lead to prolonged hospitalization and a huge economic burden to the healthcare systems. ... -
Nanoparticle-driven self-assembling injectable hydrogels provide a multi-factorial approach for chronic wound treatment
(Elsevier, 2021-07-14)
Article
Open AccessChronic wounds represent a major health burden and drain on medical system. Efficient wound repair is only possible if the dressing materials target simultaneously multiple factors involved in wound chronicity, such as ... -
Nanostructured coatings for controlling bacterial biofilms and antibiotic resistance
(Universitat Politècnica de Catalunya, 2017-01-27)
Doctoral thesis
Open AccessThe accelerated emergence of drug resistant bacteria is one of the most serious problems in healthcare and the difficulties in finding new antibiotics make it even more challenging. To overcome the action of antibiotics ... -
Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria
(2017-04-10)
Article
Open AccessThe increased emergence of antibiotic-resistant bacteria is a growing public health concern, and although new drugs are constantly being sought, the pace of development is slow compared with the evolution and spread of ... -
Novel lignin-capped silver nanoparticles against multidrug resistant bacteria
(2021-05-04)
Article
Open AccessThe emergence of bacteria resistant to antibiotics and the resulting infections are increasingly becoming a public health issue. Multidrug-resistant (MDR) bacteria are responsible for infections leading to increased morbidity ... -
Poly(sulfobetaine methacrylate)/poly(ethylene glycole) hydrogels for chronic wounds management
(Elsevier, 2019-05-14)
Article
Open AccessPolyzwitterions (PZI) recently emerged as biomaterials with excellent bio- and haemo-compatibility, demonstrating lower protein adsorption on their surfaces even compared to the golden standard in the field – poly(ethylene ... -
Quorum-quenching and matrix-degrading enzymes in multilayer coatings synergistically prevent bacterial biofilm formation on urinary catheters
(2015-12-02)
Article
Open AccessBacteria often colonize in-dwelling medical devices and grow as complex biofilm communities of cells embedded in a self-produced extracellular polymeric matrix, which increases their resistance to antibiotics and the host ... -
Simultaneous ultrasound-assisted hybrid polyzwitterion/antimicrobial peptide nanoparticles synthesis and deposition on silicone urinary catheters for prevention of biofilm-associated infections
(2021-11-21)
Article
Open AccessNosocomial infections caused by antibiotic-resistant bacteria are constantly growing healthcare threats, as they are the reason for the increased mortality, morbidity, and considerable financial burden due to the poor ... -
Smart bactericidal textile enabling in-situ visual assessment of antimicrobial activity
(Elsevier, 2025-06-01)
Article
Open AccessHospital fabrics and wound dressings with antibacterial properties are essential to minimize infection risks associated with bacterial colonization of textiles. A key challenge of these materials lies in the difficulty in ... -
Smart sensing fabrics for live bacteria detection
(Multidisciplinary Digital Publishing Institute (MDPI), 2018-11-27)
Article
Open AccessA smart textile for live bacteria detection of antimicrobial hospital tissues is here proposed. The capacity to detect viable bacteria is based on the use of Prussian Blue (PB) as electrochromic compound, with a clear ... -
Sono-enzymatically embedded antibacterial silver-lignin nanoparticles on cork filter material for water disinfection
(Multidisciplinary Digital Publishing Institute (MDPI), 2022-10-02)
Article
Open AccessProviding clean drinking water is a great challenge worldwide, especially for low-income countries where the access to safe water is limited. During the last decade, new biotechnological approaches have been explored to ... -
Sonochemical coating of Prussian Blue for the production of smart bacterial-sensing hospital textiles
(2020-08-27)
Article
Open AccessIn healthcare facilities, environmental microbes are responsible for numerous infections leading to patient’s health complications and even death. The detection of the pathogens present on contaminated surfaces is crucial, ...
