Browsing by Author "Mas Moruno, Carlos"
Now showing items 21-40 of 79
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Chemically diverse multifunctional peptide platforms with antimicrobial and cell adhesive properties
Martín Gómez, Helena; Oliver Cervelló, Lluís; Buxadera Palomero, Judit; Ginebra Molins, Maria Pau; Mas Moruno, Carlos (2020-01-01)
Article
Open AccessBacterial infections and incomplete biomaterial integration are major problems that can lead to the failure of medical implants. However, simultaneously addressing these two issues remains a challenge. Here, we present a ... -
Co-localization of RGD and PHSRN peptides on titanium to guide stem cell behaviour and enhance Implant osteointegration
Fraioli, Roberta; Manero Planella, José María; Gil Mur, Francisco Javier; Mas Moruno, Carlos (2015)
Conference lecture
Open Access -
Comparison of the antibacterial effect of silver nanoparticles and a multifunctional antimicrobial peptide on titanium surface
Moreno Duarte, Daniel; Buxadera Palomero, Judit; Ginebra Molins, Maria Pau; Manero Planella, José María; Martín Gómez, Helena; Mas Moruno, Carlos; Rodríguez Rius, Daniel (Multidisciplinary Digital Publishing Institute (MDPI), 2023-06-04)
Article
Open Access
Covenantee: Institut de Recerca Sant Joan de Déu / Institut de Bioenginyeria de CatalunyaTitanium implantation success may be compromised by Staphylococcus aureus surface colonization and posterior infection. To avoid this issue, different strategies have been investigated to promote an antibacterial character ... -
Conformational control of integrin subtype selectivity in isoDGR peptide motifs: A biological switch
Frank, A.O.; Otto, E.; Mas Moruno, Carlos; Schiller, H.; Marinelli, L.; Cosconati, S.; Bochen, A.; Vossmeyer, D.; Zahn, G.; Stragies, R.; Novellino, E.; Kessler, H. (2010)
Article
Restricted access - publisher's policyThumbnail image of graphical abstract The rearrangement of asparagine to isoaspartate (isoD) is responsible for the deactivation of many functional proteins. However, the isoDGR motif, which is optimally presented as a ... -
Control of stem cell response and bone growth on biomaterials by fully non-peptidic integrin selective ligands
Fraioli, Roberta; Neubauer, Stefanie; Rechenmacher, Florian; Bosch Canals, Begoña María; Dashnyam, Khandmaa; Kim, Joong-Hyun; Gil Mur, Francisco Javier; Ginebra Molins, Maria Pau; Manero Planella, José María; Mas Moruno, Carlos (Royal Society of Chemistry (RSC), 2019-04-01)
Article
Open Access
Covenantee: Technische Universität München / Universitat Internacional de Catalunya / Tan'guk Taehakkyo / Institut de Bioenginyeria de CatalunyaIn this communication we report that anchoring avß3 or a5ß1 integrin-selective RGD peptidomimetics to titanium efficiently tunes mesenchymal stem cell response in vitro and bone growth in rat calvarial defects. Our results ... -
Covalent immobilization of hLf1-11 peptide on a titanium surface reduces bacterial adhesion and biofilm formation
Godoy Gallardo, Maria; Mas Moruno, Carlos; Fernandez Calderon, Maria C.; Perez Giraldo, Ciro; Manero Planella, José María; Albericio, Fernando; Gil Mur, Francisco Javier; Rodríguez Rius, Daniel (2014-08-01)
Article
Restricted access - publisher's policyBacterial infection represents a major cause of implant failure in dentistry. A common approach to overcoming this issue and treating pen-implant infection consists in the use of antibiotics. However, the rise of ... -
Customized interface biofunctionalization of decellularized extracellular matrix: towards enhanced endothelialization
Aubin, Hugh; Mas Moruno, Carlos; Iijima, Makoto; Schütterle, Nicolas; Steinbrink, Meike; Assmann, Alexander; Gil Mur, Francisco Javier; Lichtenberg, Artur; Pegueroles Neyra, Marta; Akhyari, Payam (2016)
Article
Restricted access - publisher's policy
Covenantee: Heinrich-Heine Universität DüsseldorfInterface biofunctionalization strategies try to enhance and control the interaction between implants and host organism. Decellularized extracellular matrix (dECM) is widely used as a platform for bioengineering of medical ... -
Cyclic azapeptide integrin ligand synthesis and biological activity
Spiegel, J.; Mas Moruno, Carlos; Kessler, H.; Lubell, W.D. (2012)
Article
Restricted access - publisher's policyAza-peptides are obtained by replacement of the α-C-atom of one or more amino acids by a nitrogen atom in a peptide sequence. Introduction of aza-residues into peptide sequences may result in unique structural and ... -
Design and facile solid-phase synthesis of peptide-based LPS-inhibitors containing PEG-like functionalities
Mas Moruno, Carlos; Cascales, L.; Mora, P.; Cruz, L.J.; Perez-Paya, E.; Albericio, F. (Wiley, 2009)
Article
Restricted access - publisher's policyLPS release from Gram-negative bacteria can result in sepsis, a serious systemic inflammatory response to infection that can lead to septic shock and multiple organ failure. Thus, easy-to-synthesize, effective, and safe ... -
Design of a minimized cyclic tetrapeptide that neutralizes bacterial endotoxins
Mora, Puig; Mas Moruno, Carlos; Tamborero, Silvia; Cruz, Luis Javier; Pérez-Payá, Enrique; Albericio, Fernando (2006)
Article
Restricted access - publisher's policySeptic shock is a leading cause of mortality in intensive care patients, and no specific drugs are as yet available for its treatment. Therefore, new leads ar e required in order to increase the numbe r of active ... -
Dual peptide functionalization of Zn alloys to enhance endothelialization for cardiovascular applications
García Mintegui, Claudia; Chausse Calbet, Victor; Labay, Cédric Pierre; Mas Moruno, Carlos; Ginebra Molins, Maria Pau; Cortina Pallás, José Luis; Pegueroles Neyra, Marta (Elsevier, 2024-02-01)
Article
Open Access
Covenantee: Institut de Bioenginyeria de CatalunyaA new generation of fully bioresorbable metallic Zn-based alloys could be used for stenting applications; however, the initial surface degradation delays stent re-endothelialization. Thus, this work proposes a dual strategy ... -
Editorial: “Peptides in biomaterials science: New trends and applications”
Mas Moruno, Carlos (2022-01)
Article
Open Access -
Effect of nanosecond laser texturing on the topography, low-temperature degradation behaviour and biological performance of 3Y-TZP
García de Albéniz López de Aberasturi, Nerea; Jiménez Piqué, Emilio; Roa Rovira, Joan Josep; Mas Moruno, Carlos (Universitat Politècnica de Catalunya, 2022-06-16)
Conference lecture
Open Access -
Effectiveness of direct laser interference patterning and peptide immobilization on endothelial cell migration for cardio-vascular applications: an in vitro study
Schieber, Romain; Mas Moruno, Carlos; Lasserre, Federico; Roa Rovira, Joan Josep; Ginebra Molins, Maria Pau; Mücklich, Frank T.; Pegueroles Neyra, Marta (2022-04-01)
Article
Open Access
Covenantee: Universität des Saarlandes / Institut de Bioenginyeria de CatalunyaEndothelial coverage of an exposed cardiovascular stent surface leads to the occurrence of restenosis and late-stent thrombosis several months after implantation. To overcome this difficulty, modification of stent surfaces ... -
Evolution of microstructure and residual stresses in gradually ground/polished 3Y-TZP
Minguela Díaz, Joaquim; Slawik, Sebastian; Mücklich, Frank T.; Ginebra Molins, Maria Pau; Llanes Pitarch, Luis Miguel; Mas Moruno, Carlos; Roa Rovira, Joan Josep (Elsevier, 2019-01-01)
Article
Open Access
Covenantee: Universität des Saarlandes / Institut de Bioenginyeria de CatalunyaA comprehensive study of progressively ground/polished 3Y-TZP was performed with the aim of better understanding the mechanisms driving the microstructural modifications observed after such procedures, and identifying the ... -
Funcionalización de superfícies anti-fouling sobre titanio para mejora de sus propiedades
Buxadera-Palomero, Judit; Mas Moruno, Carlos; Rodríguez Rius, Daniel; Manero Planella, José María (2018-09-01)
Article
Open Access -
Functionalization of 3D printed polymeric bioresorbable stents with a dual cell-adhesive peptidic platform combining RGDS and YIGSR sequences
Chausse Calbet, Victor; Mas Moruno, Carlos; Martín Gómez, Helena; Pino Curto, Marc; Díaz Ricart, Maribel; Escolar Albaladejo, Ginés; Ginebra Molins, Maria Pau; Pegueroles Neyra, Marta (Royal Society of Chemistry (RSC), 2023-05-08)
Article
Open Access
Covenantee: Institut de Recerca Sant Joan de Déu / Hospital Clínic i Provincial de Barcelona / Institut de Bioenginyeria de CatalunyaBiomimetic surface modification with cell-adhesive peptides is a promising approach to improve endothelialization of current bioresorbable stents (BRS). Among them, RGDS and YIGSR sequences have been reported to mediate ... -
Functionalization of alginate hydrogels with a multifunctional peptide supports mesenchymal stem cell adhesion and reduces bacterial colonization
Oliver Cervelló, Lluís; López Gómez, Patricia Victoria; Martín Gómez, Helena; Marion, Mahalia; Ginebra, Maria Pau; Mas Moruno, Carlos (2024-08-22)
Article
Restricted access - publisher's policyHydrogels with cell adhesive moieties stand out as promising materials to enhance tissue healing and regeneration. Nonetheless, bacterial infections of the implants represent an unmet major concern. In the present work, ... -
Functionalization of CoCr surfaces with cell adhesive peptides to promote HUVECs adhesion and proliferation
Castellanos, Maria Isabel; Mas Moruno, Carlos; Grau, Anna; Serra-Picamal, Xavier; Trepat, Xavier; Albericio Palomera, Fernando; Joner, Michael; Gil Mur, Francisco Javier; Ginebra Molins, Maria Pau; Manero Planella, José María; Pegueroles Neyra, Marta (2017-01-30)
Article
Open Access
Covenantee: Center for Research in NanoEngineering (CRNE) / Deutsches Herzzentrum München / Institut de Bioenginyeria de CatalunyaBiomimetic surface modification with peptides that have specific cell-binding moieties is a promising approach to improve endothelialization of metal-based stents. In this study, we functionalized CoCr surfaces with RGDS, ... -
Functionalizing avß3- or a5ß1-selective integrin antagonists for surface coating: A new tool to discriminate integrin subtypes in vitro
Rechenmacher, Florian; Neubauer, Stefanie; Polleux, Julien; Mas Moruno, Carlos; De Simone, Mariarosaria; Cavalcanti-Adam, Elisabetta Ada; Spatz, Joachim P.; Fässler, Reinhard; Kessler, Horst (2013)
Article
Restricted access - publisher's policyThumbnail image of graphical abstract Stuck with the right choice: avß3- or a5ß1-selective integrin ligands were functionalized for surface coating without losing activity and selectivity. The coating of nanostructured ...