Now showing items 21-40 of 45

  • Diffusion-reaction model for Drosophila embryo development 

    Allena, Rachele; Muñoz Romero, José; Aubry, Denis (Gordon and Breach Science Publishers, 2011-10-04)
    Article
    Open Access
    During the early stages of gastrulation in Drosophila embryo, the epithelial cells composing the single tissue layer of the egg undergo large strains and displacements. These movements have been usually modeled by decomposing ...
  • Forces driving epithelial wound healing 

    Muñoz Romero, José; Gupta, Makund; Ladux, Benoit; Trepat Guixer, Xavier (2014-09-01)
    Article
    Open Access
    A fundamental feature of multicellular organisms is their ability to self-repair wounds through the movement of epithelial cells into the damaged area. This collective cellular movement is commonly attributed to a combination ...
  • Hybrid cell centred/vertex model for cellular nanolayers 

    Mosaffa, Payman; Asadipour, Nina; Millán, Daniel; Rodríguez Ferran, Antonio; Muñoz Romero, José (2015)
    Conference report
    Open Access
    Macroscopic deformations in embryonic soft tissues are due to the intra-cellular remodelling and cell intercalation. We here present a computational approach that can handle the two types of deformations, and also take ...
  • Hybrid cell centred/vertex model for large tissue deformations 

    Muñoz Romero, José; Mosaffa, Payman; Mao, Yanlan; Tetley, Rob; Asadipour, Nina; Rodríguez Ferran, Antonio (2016)
    Conference report
    Open Access
    Macroscopic deformations in embryonic soft tissues are due to the intra-cellular remodelling and cell intercalation. We here present a computational approach that can handle the two types of deformations, and also take ...
  • Hybrid cell-centred/vertex model for multicellular systems with equilibrium-preserving remodelling 

    Mosaffa, Payman; Rodríguez Ferran, Antonio; Muñoz Romero, José (John Wiley & sons, 2018-03)
    Article
    Open Access
    We present a hybrid vertex/cell-centred model for mechanically simulating planar cellular monolayers undergoing cell reorganisation. Cell centres are represented by a triangular nodal network, while the cell boundaries are ...
  • Mapping forces and kinematics during collective cell migration 

    Serra-Picamal, Xavier; Conte, Vito; Sunyer, Raimon; Muñoz Romero, José; Trepat, Xavier (2015-01-08)
    Article
    Restricted access - publisher's policy
    Fundamental biological processes including morphogenesis and tissue repair require cells to migrate collectively. In these processes, epithelial or endothelial cells move in a cooperative manner coupled by intercellular ...
  • Master-slave approach for the modelling of joints with dependent degrees of freedom in flexible mechanisms 

    Muñoz Romero, José; Jelenic, Gordan; Crisfield, M. A. (2003-08-06)
    Article
    Open Access
    The analysis of multibody systems requires an exact description of the kinematics of the joints involved. In the present work the master–slave approach is employed and endowed with the possibility of including several more ...
  • Mechanical oscillations in biological tissues as a result of delayed rest-length changes 

    Muñoz Romero, José; Dingle, Monica; Wenzel, Manuel (American Institute of Physics (AIP), 2018-11-26)
    Article
    Open Access
    Oscillatory behavior in tissue biology is ubiquitous and may be observed in the form of either chemical or mechanical signals. We present here and solve a mechanical cell model that exhibits oscillations emerging from ...
  • Modelling of mixed damage on fibre reinforced composite laminates subjected to low velocity impact 

    Curiel Sosa, José Luis; Phaneendra, S.; Muñoz Romero, José (2013)
    Article
    Open Access
  • Modelling unilateral frictionless contact using the null-space method and cubic B-Spline interpolation 

    Muñoz Romero, José (2008-02)
    Article
    Open Access
    The analysis of unilateral sliding contact in elasticity is equivalent to a minimisation problem subjected to a set of inequality constraints. However, the presence of boundary discontinuities, such as those stemming from ...
  • Non-regularised inverse finite element analysis for 3D traction force microscopy 

    Muñoz Romero, José (2016-06-10)
    Article
    Open Access
    The tractions that cells exert on a gel substrate from the observed displacements is an increasingly attractive and valuable information in biomedical experiments. The computation of these tractions requires in general ...
  • Numerical modelling of multicellular dynamics 

    Muñoz Romero, José; Asadipour, Nina; Mosaffa, P; Conte, V (EUETIB, 2013-12)
    Conference lecture
    Open Access
    En este trabajo se desarrollar un modelo computacional que permite simular y predecir las deformaciones sucesivas que tienen lugar durante fases de la embriogénesis que han sido biológicamente bien detalladas. Las simulaciones ...
  • On the modelling of incompressibility in linear and non-linear elasticity with the master-slave approach 

    Muñoz Romero, José (Wiley and Sons, 2008-04)
    Article
    Open Access
    The master-slave approach is adapted to model the kinematic constraints encountered in incompressibility. The method presented here allows us to obtain discrete displacement and pressure fields for arbitrary finite element ...
  • On the numerical simulation of fatigue driven delamination with interface elements 

    Muñoz Romero, José; Galvanetto, Ugo; Robinson, Paul (2006-10)
    Article
    Open Access
  • Physiology-based model of cell viscoelasticity 

    Muñoz Romero, José; Albo Guijarro, Santiago (2013)
    Article
    Open Access
    The measured viscoelastic properties of biological tissues is the result of the passive and active response of the cells. We propose an evolution law of the remodeling process in the cytoskeleton which is able to mimic the ...
  • Porous-based rheological model for tissue fluidisation 

    Asadipour, Nina; Trepat, Xavier; Muñoz Romero, José (2016-11-01)
    Article
    Restricted access - publisher's policy
    It has been experimentally observed that cells exhibit a fluidisation process when subjected to a transient stretch, with an eventual recovery of the mechanical properties upon removal of the applied deformation. This ...
  • R-adaptivity in limit analysis 

    Muñoz Romero, José; Hambleton, James; Sloan, Scott (Springer, 2017-10-04)
    Part of book or chapter of book
    Restricted access - publisher's policy
    Direct methods aim to find the maximum load factor that a domain made of a plastic material can sustain before undergoing full collapse. Its analytical solution may be posed as a constrained maximisation problem, which is ...
  • Robust mechanisms of ventral furrow invagination require the combination of cellular shape changes 

    Conte, Vito; Muñoz Romero, José; Baum, Buzz; Miodownik, M. (2009-05)
    Article
    Open Access
    Ventral furrow formation in Drosophila is the first large-scale morphogenetic movement during the life of the embryo, and is driven by co-ordinated changes in the shape of individual epithelial cells within the cellular ...
  • Simulation of damage on laminates 

    Curiel Sosa, José Luis; Muñoz Romero, José; Pinho, S.T.; Li, Q.; Beg, O.A. (2012)
    Conference lecture
    Open Access
    An experimental study on controlled faulty perturbed flexible structures is developed using an active mass damper actuator, where the flexible structure is subject to external perturbation and sensor faults. To attenuate ...
  • Sliding contact conditions using the master-slave approach with application on geometrically non-linear beams 

    Muñoz Romero, José; Jelenic, Gordan (2004)
    Article
    Open Access
    Frictionless sliding conditions between two bodies are usually defined using either the method of Lagrangian multipliers or by prescribing an artificial (penalty) stiffness which resists the penetration at the contact ...