Ara es mostren els items 21-40 de 56

  • Escherichia coli and pseudomonas aeruginosa eradication by nano-penicillin G 

    Macedo Fernandes, Margarida Maria; Ivanova, Kristina Dimitrova; Francesko, Antonio; Rivera, Diana; Torrent Burgués, Juan; Mendoza Gómez, Ernesto; Tzanov, Tzanko (2016-06-09)
    Article
    Accés obert
    The transformation of penicillin G into nano/micro-sized spheres (nanopenicillin) using sonochemical technology was explored as a novel tool for the eradication of Gram-negative bacteria and their biofilms. Known by its ...
  • Functional biopolymer-based matrices for modulation of chronic wound enzyme activities 

    Francesko, Antonio; Soares da Costa, Diana; Reis, Rui L.; Pashkuleva, Iva; Tzanov, Tzanko (2012-10-13)
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    Accés restringit per política de l'editorial
    Collagen, collagen/hyaluronic acid (HA) and collagen/HA/chitosan (CS) sponges loaded with epigallocatechin gallate (EGCG), catechin (CAT) and gallic acid (GA) were developed and evaluated as active chronic wound dressings. ...
  • GAGs-thiolated chitosan assemblies for chronic wounds treatment: control of enzyme activity and cell attachment 

    Francesko, Antonio; Soares da Costa, Diana; Lisboa, Patricia; Reis, Rui L.; Tzanov, Tzanko; Iva Hristova, Pashkuleva (2012-04-20)
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    Multilayered polyelectrolyte coatings comprising thiolated chitosan (TC) and glycosaminoglycans (GAGs), chondroitin sulphate and hyaluronic acid, were built using a layer-by-layer approach. The surface activity of these ...
  • Hybrid chitosan-silver nanoparticles enzymatically-embedded on cork filter material for water disinfection 

    Garcia Peña, Lina Vanesa; Petkova, Petya; Margalef-Marti, Rosanna; Vives, Marc; Aguilar, Lorena; Gallegos, Angel; Francesko, Antonio; Perelshtein, Ilana; Gedanken, Aharon; Mendoza Gómez, Ernesto; Casas-Zapata, Juan Carlos; Morató Farreras, Jordi; Tzanov, Tzanko (2017-04-05)
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    Accés restringit per política de l'editorial
    Microbial contamination remains a major challenge in supply of drinking water in developing regions, despite the continuous advances being made in water purification processes. The spread and transmission of pathogens due ...
  • Hydrogel dressings for advanced wound management 

    Francesko, Antonio; Petkova, Petya; Tzanov, Tzanko (2018-12)
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    Accés obert
    Composed in a large extent of water and due to their non-adhesiveness, hydrogels found their way to the wound dressing market as materials that provide a moisture environment for healing while being comfortable to the ...
  • Immobilization of antimicrobial core-shell nanospheres onto silicone for prevention of Escherichia coli biofilm formation 

    Macedo Fernandes, Margarida Maria; Ivanova, Kristina Dimitrova; Mendoza Gómez, Ernesto; Tzanov, Tzanko; Francesko, Antonio (2016-09-16)
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    Accés obert
    Escherichia coli (E. coli) strains are among the most frequently isolated microorganisms in urinary tract infections able to colonize the surface of urinary catheters and form biofilms. These biofilms are highly resistant ...
  • Inhibition of deleterious chronic wound enzymes with plant polyphenols 

    Díaz González, María; Rocasalbas Lozano, Guillem; Francesko, Antonio; Touriño Eirín, Sonia; Torres, Josep Lluis; Tzanov, Tzanko (2012-01-18)
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    Accés restringit per política de l'editorial
    The chronic wound environment is characterized by high concentrations of reactive oxygen species (ROS) and elevated levels of myeloperoxidase (MPO) and collagenases, together impairing the healing process. Therefore, the ...
  • Inhibition of quorum-sensing: A new paradigm in controlling bacterial virulence and biofilm formation 

    Asenova Ivanova, Aleksandra; Ivanova, Kristina Dimitrova; Tzanov, Tzanko (Springer Nature, 2018-05-31)
    Capítol de llibre
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    Bacterial pathogens coordinate the expression of multiple virulence factors and formation of biofilms in cell density dependent manner, through a phenomenon named quorum sensing (QS). Protected in the biofilm community, ...
  • Innovative approaches for controlling clinically relevant biofilms: current trends and future prospects 

    Ivanova, Kristina Dimitrova; Tzanov, Tzanko; Hoyo, Javier; Ramon, Eva (2017-01-05)
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    Accés obert
    Bacteria that colonize and form biofilms on living tissues and medical devices are a global healthcare concern. They cause life threatening infections and are associated with increased mortality and morbidity in the ...
  • In situ chitosan gelation initiated by atmospheric plasma treatment 

    Molina, Ricardo; Jovancic, P.; Vilchez, S.; Tzanov, Tzanko; Solans, C. (2014-01-06)
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  • Laccase-assisted formation of bioactive chitosan/gelatin hydrogel stabilized with plant polyphenols 

    Rocasalbas Lozano, Guillem; Francesko, Antonio; Touriño Eirín, Sonia; Fernández Francos, Xavier; Guebitz, Georg M.; Tzanov, Tzanko (2012-11-02)
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    Laccase-assisted simultaneous cross-linking and functionalization of chitosan/gelatin blends with phenolic compounds from Hamamelis virginiana was investigated for the development of bioactive hydrogel dressings. The ...
  • Layer-by-layer decorated nanoparticles with tunable antibacterial and antibiofilm properties against both gram-positive and gram-negative bacteria 

    Asenova Ivanova, Aleksandra; Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Sanchez-Gomez, Susana; Heinze, Thomas; Tzanov, Tzanko (2018-01-09)
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    Accés obert
    acteria-mediated diseases are a global healthcare concern due to the development and spread of antibiotic resistant strains. Cationic compounds are considered membrane active biocidal agents having a great potential to ...
  • Making the hospital a safer place by sonochemical coating of all its textiles with antibacterial nanoparticles 

    Perelshtein, Ilana; Lipovsky, Anat; Perkas, Nina; Tzanov, Tzanko; Arguirova, M; Leseva, Marya D.; Gedanken, Aharon (2015-01-28)
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    Accés obert
    The ability to scale-up the sonochemical coating of medical textiles with antibacterial nanoparticles is demonstrated in the current paper. A roll-to-roll pilot installation to coat textiles was built taking into consideration ...
  • Metal-enzyme nanoaggregates eradicate both gram-positive and gram-negative bacteria and their biofilms 

    Ferreres Cabanes, Guillem; Bassegoda Puigdomenech, Arnau; Hoyo Pérez, Javier; Torrent Burgués, Juan; Tzanov, Tzanko (2018-11-13)
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    Accés restringit per política de l'editorial
    To palliate the appearance of antimicrobial resistance (AMR), the use of bactericidal agents acting differently than conventional antibiotics and the elimination of bacterial biofilm, are the two most promising strategies. ...
  • Multifunctional enzymatically generated hydrogels for chronic wound application 

    Stefanov, Ivaylo; Hoyo Pérez, Javier; Cailloux, Jonathan; Santana Pérez, Orlando Onofre; Tzanov, Tzanko; Pérez Rafael, Silvia; Hinojosa-Caballero, Dolores (2017-04-19)
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    Accés restringit per política de l'editorial
    The healing of chronic wounds requires intensive medical intervention at huge healthcare costs. Dressing materials should consider the multifactorial nature of these wounds comprising deleterious proteolytic and oxidative ...
  • Multifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort 

    Hoyo Pérez, Javier; Ivanova, Kristina Dimitrova; Guaus Guerrero, Ester; Tzanov, Tzanko (2019-02-13)
    Article
    Accés restringit per política de l'editorial
    Contact lenses (CL) provide visual correction but their use may also induce several adverse effects causative of discomfort and conditions that lead to stop or discontinue their use. Discomfort is mainly caused by insufficient ...
  • Nanotransformation of vancomycin overcomes the intrinsic resistance of Gram-negative bacteria 

    Ivanova, Kristina Dimitrova; Hoyo Pérez, Javier; Francesko, Antonio; Tzanov, Tzanko; Fernandes, Margarida M.; Pérez Rafael, Silvia (2017-04-10)
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    Accés obert
    The increased emergence of antibiotic-resistant bacteria is a growing public health concern, and although new drugs are constantly being sought, the pace of development is slow compared with the evolution and spread of ...
  • New myeloperoxidase detection system based on enzyme-catalysed oxidative synthesis of a dye for paper-based diagnostic devices 

    Bassegoda Puigdomenech, Arnau; Ferreres Cabanes, Guillem; Pérez Rafael, Silvia; Hinojosa-Caballero, Dolores; Torrent Burgués, Juan; Tzanov, Tzanko (2018-10-21)
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    The severity and cost of wound infections strongly demands for simple and fast methods for wound infection determination. Point-of-care testing devices play a crucial role in order to achieve a fast diagnosis and early ...
  • One-step preparation of multifunctional chitosan microspheres by a simple sonochemical method 

    Skirtenko, Natalia; Tzanov, Tzanko; Gedanken, Aharon; Rahimipour, Shai (2010)
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    Chitosan is a biodegradable natural polymer with great potential for pharmaceutical applications due to its biocompatibility, high charge density, nontoxicity, and mucoadhesion properties. Processing techniques for the ...
  • One-step sonochemical preparation of redox-responsive nanocapsules for glutathione mediated RNA release 

    Francesko, Antonio; Macedo Fernandes, Margarida Maria; Tzanov, Tzanko; Perelshtein, Illana; Benisvy Aharonovich, Lena; Gedanken, Aharon (Royal Society of Chemistry, 2014-07-09)
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    Efficient RNA delivery to targeted cells requires the use of stable interactive carriers that provide RNA protection during the extracellular transit and trigger release once internalised. One strategy to avoid the premature ...