Now showing items 21-34 of 34

  • Models no-lineals d'efectes mixtes per estudiar la dinàmica viral de pacients infectats pel VIH 

    López Blázquez, Raquel (Universitat Politècnica de Catalunya, 2006-12)
    Master thesis (pre-Bologna period)
    Open Access
    Objectiu: Valorar si I'Enfurvitide (ENF; T-20) augmenta I'activitat antiviral d'una combinació de quatre fàrmacs antirretrovirals (Lopinavir/Ritonavir. Efavirenz, Lamivudina í Tenofovir) en pacíents infectats pel VIH que ...
  • Regression and residual analysis in linear models with interval censored data 

    Topp, Rebekka (Universitat Politècnica de Catalunya, 2002-07-19)
    Doctoral thesis
    Open Access
    This work consists of two parts, both related with regression analysis for interval censored data. Interval censored data x have the property that their value cannot be observed exactly but only the respective interval ...
  • Regression models with an interval-censored covariate 

    Langohr, Klaus (Universitat Politècnica de Catalunya, 2004-06-16)
    Doctoral thesis
    Open Access
    El análisis de supervivencia trata de la evaluación estadística de variables que miden el tiempo transcurrido hasta un evento de interés. Una particularidad que ha de considerar el análisis de supervivencia son datos ...
  • Relative efficiency between two tests 

    Bofill Roig, Marta (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2016-06)
    Master thesis
    Restricted access - author's decision
    The choice of the primary endpoint is an important issue when designing a clinical trial. The motivation of this Master thesis is to develop a methodology based on the Asymptotic Relative Efficiency (ARE) that discerns ...
  • Sample size computation for binary composite endpoints 

    Bertran Melines, Alexandra (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2015-10)
    Master thesis
    Restricted access - author's decision
    Covenantee:  Hospital Universitari Vall d'Hebron
    In this project we propose a way of computing the needed sample size, for a binary endpoint and for a binary composite endpoint, needed to detect the effect of a certain treatment considering a type I error of alpha and a ...
  • Statistical efficiency of survival endpoints in breast cancer clinical trials 

    Ferrer Playan, Jordi (Universitat Politècnica de Catalunya, 2012-07)
    Master thesis
    Open Access
    Per demostrar l'eficàia d'una nova teràpia, en assajos clínics en càncer es recomana l'ús d'endpoints basats en la supervivència. D'entre ells, les principals agències reguladores (FDA i EMA) recomanen l'ús d' Overall ...
  • Statistical metidos applied to volcanology and volcanic hazard assessment 

    Sobradelo Pérez, Rosa Maria (Universitat Politècnica de Catalunya, 2011-07-21)
    Doctoral thesis
    Open Access
    Disasters are large intractable problems that test the ability of communities and nations to effectively protect their populations and infrastructure, to reduce both human and property loss, and to rapidly recover. The ...
  • Study and validation of data structures with missing values. Application to survival analysis 

    Serrat Piè, Carles (Universitat Politècnica de Catalunya, 2001-05-21)
    Doctoral thesis
    Open Access
    En aquest treball tractem tres metodologies diferents -no paramètrica, paramètrica i semiparamètrica- per tal de considerar els patrons de dades amb valors no observats en un context d'anàlisi de la supervivència. Les dues ...
  • Study of the therapeutic drug adherence in patients with ischemic cardiopathology 

    Carbonell Mirabent, Pere Josep (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2015-06)
    Master thesis
    Open Access
    The present study is divided into two different parts. The first part will be devoted to detect risk factors for the non adherence to treatment in patients with isquemic cardiopathology. The aim of the second part of the ...
  • Survival analysis issues with interval-censored data 

    Oller Piqué, Ramon (Universitat Politècnica de Catalunya, 2006-06-30)
    Doctoral thesis
    Open Access
    L'anàlisi de la supervivència s'utilitza en diversos àmbits per tal d'analitzar dades que mesuren el temps transcorregut entre dos successos. També s'anomena anàlisi de la història dels esdeveniments, anàlisi de temps de ...
  • Survival data analysis with heavy-censoring and long-term survivors 

    López Segovia, Lucas (Universitat Politècnica de Catalunya, 2014-06-10)
    Doctoral thesis
    Open Access
    The research developed in this thesis has been motivated by two datasets, which are introduced in Chapter 2, one concerning the mortality of calves from birth to weaning while the other refers to survival of patients ...
  • Testing Goodness-of-Fit of Parametric Survival Models for Right Censored Data 

    Besalú Mayol, Mireia (Universitat Politècnica de Catalunya / Universitat de Barcelona, 2016-06)
    Master thesis
    Open Access
    The main goal of this work it is to present a review of the existing methods to deal with the goodness-of-fit for right-censored data. Goodness-of-fit tests are developed to assess whether a given distribution is suited ...
  • The analysis of interval-censored survival data. From a Nonparametric perspective to a nonparametric Bayesian approach 

    Calle, M. Luz (Universitat Politècnica de Catalunya, 1997-02-27)
    Doctoral thesis
    Open Access
    This work concerns some problems in the area of survival analysis that arise in real clinical or epidemiological studies. In particular, we approach the problem of estimating the survival function based on interval-censored ...
  • Using Gumbel copula to assess the efficiency of the main endpoint in a randomized clinical trial and comparison with Frank copula 

    Plana Ripoll, Oleguer (Universitat Politècnica de Catalunya, 2012-07-13)
    Master thesis
    Open Access
    In time-to-event randomized clinical trials, it is common to use composite endpoints as the main endpoint when comparing two treatment groups. A new statistical methodology has been recently developed in order to derives ...