Now showing items 21-40 of 53

  • Heavy right censoring: when is too heavy? 

    López-Segovia, Lucas; Gómez Melis, Guadalupe; Espinal Berenguer, Anna (2009)
    Conference report
    Restricted access - publisher's policy
    The main purpose of this work is to study the effect that a large percentage of right censoring has on the estimation of the regression parameters under a proportional hazards model. To accomplish this we conduct a simulation ...
  • High risk and probability of progression to osteoporosis at 10 years in HIV-infected individuals: the role of PIs 

    Negredo Puigmal, Eugènia; Langohr, Klaus; Bonjoch Badia, Anna; Pérez Álvarez, Nuria; Estany Quera, Carla; Puig, Jordi; Echevarría, Patricia; Clotet Sala, Bonaventura; Gómez Melis, Guadalupe (2018-09-01)
    Article
    Restricted access - publisher's policy
  • Identification of interleukin-27 (IL-27)/IL-27 receptor subunit alpha as a critical immune axis for in vivo hiv control 

    Ruiz-Riol, M.; Berdnik, D.; Llano, A.; Mothe, Beatriz; Gálvez, C.; Pérez Alvarez, Susana; Oriol Tordera, B.; Olvera Van der Stoep, Alex; Silva Arrieta, S.; Meulbroek, M.; Salvat Pujol, Francesc; Coll, J.; Martínez Picado, Javier; Ganoza, Carmela; Sánchez, J.; Gómez Melis, Guadalupe; Coray, Wyss; Brander, Christian (2017-08-01)
    Article
    Open Access
    Intact and broad immune cell effector functions and specific individual cytokines have been linked to HIV disease outcome, but their relative contribution to HIV control remains unclear. We asked whether the proteome of ...
  • INFERÈNCIA I DECISIÓ//INFERÈNCIA 

    Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya, 2011-01-13)
    Exam
    Restricted access to the UPC academic community
  • INFERÈNCIA I DECISIÓ//INFERÈNCIA 

    Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya, 2010-01-14)
    Exam
    Restricted access to the UPC academic community
  • INFERÈNCIA I DECISIÓ//INFERÈNCIA 

    Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya, 2009-11-09)
    Exam
    Restricted access to the UPC academic community
  • INFERÈNCIA I DECISIÓ//INFERÈNCIA 

    Gómez Melis, Guadalupe (Universitat Politècnica de Catalunya, 2012-01-18)
    Exam
    Restricted access to the UPC academic community
  • Interruptions of antiretroviral therapy in human immunodeficiency virus infection: are they detrimental to neurocognitive functioning? 

    Clotet, Bonaventura; Garolera, Maite; Muñoz Moreno, Jose A.; Fumaz, Carmina R.; Prats, Anna; Ferrer, Maria J.; Negredo, Eugènia; Pérez Álvarez, Nuria; Molto, Jose; Gómez Melis, Guadalupe (2010-06)
    Article
    Restricted access - publisher's policy
    Because interruptions of antiretroviral treatment may entail clinical risks for human immunodeficiency virus (HIV)-infected individuals, we investigated their impact on neurocognitive functioning. Cross-sectional study ...
  • Joint modelling of two sequential times to event with longitudinal information 

    Huertas, Jaime-Abel; Gómez Melis, Guadalupe; Serrat Piè, Carles (2011)
    Conference lecture
    Open Access
    In survival analysis, the lifetimes may be observed in some speci¯ed order, where the time to event Tk, cannot be observed until T1; :::; Tk¡1 have been observed. The present work proposes a joint model of two sequential ...
  • La Estadística: una cuestión de supervivencia 

    Gómez Melis, Guadalupe (2007-12-12)
    Audiovisual
    Open Access
    Podríamos empezar preguntándonos el porqué de este título. O mejor aún, el porqué de esta charla en el ciclo “La mujer: elemento innovador en la ciencia”, … Podríamos reflexionar sobre el significado de cada una de las ...
  • Mesa redonda: La Estadística en la Investigación Médica 

    Abraira Santos, Víctor; Cadarso, Carmen; Gómez Melis, Guadalupe; Martín Andrés, Antonio; Pita, Salvador (Institut d'Estadística de Catalunya, 2001)
    Article
    Open Access
    Este artículo es una transcripción de las conferencias dictadas en la mesa organizada en el 4º Congreso Galego de Estatistica y Investigación de Operacions que tuvo lugar en Santiago de Compostela en noviembre de 1999. Los ...
  • Multiple imputation approach for interval-censored time to HIV RNA viral rebound within a mixed effects Cox model 

    Alarcón Soto, Yovaninna; Langohr, Klaus; Fehér, C.; García Alcaide, Felipe; Gómez Melis, Guadalupe (2018-01-01)
    Article
    Open Access
    We present a method to fit a mixed effects Cox model with interval-censored data. Our proposal is based on a multiple imputation approach that uses the truncated Weibull distribution to replace the interval-censored data ...
  • Nonlinear transformation models: application to mortality of calves 

    López-Segovia, Lucas; Espinal Berenguer, Anna; Gómez Melis, Guadalupe (2010)
    Conference report
    Open Access
    We present. an appl ication of the proportional hazard-proportional hazard cure models to evalu ate the environmental and genetic factors that affect both mortality and survival up to weaning of beef calves. We usc the ...
  • Quantile estimation of the rejection distribution of food products integrating assessor values and interval-censored consumer data 

    Langohr, Klaus; Gómez Melis, Guadalupe; Hough, Guillermo (2013-12)
    Article
    Restricted access - publisher's policy
    Fitting parametric survival models with interval-censore d data is a common task in survival analysis and implemented in many statistical software pack ages. Here, we present a novel approach to fit such models if the ...
  • Recommendations to choose the primary endpoint in cardiovascular clinical trials 

    Gómez Melis, Guadalupe; Gómez Mateu, Moisés; Dafni, Urania (2013)
    External research report
    Open Access
    Background – A composite endpoint is often used as the primary endpoint to assess the efficacy of a new treatment in randomized clinical trials (RCT). In cardiovascular trials, the often rare event of the relevant primary ...
  • Review of multivariate survival data 

    Gómez Melis, Guadalupe; Calle Rosingana, M. Luz; Serrat Piè, Carles; Espinal Berenguer, Anna (2004-09)
    External research report
    Open Access
    This paper reviews some of the main contributions in the area of multivariate survival data and proposes some possible extensions. In particular, we have concentrated our search and study on those papers that are relevant ...
  • Selecting the primary endpoint in a randomized clinical trial: the ARE method 

    Plana-Ripoll, Oleguer; Gómez Melis, Guadalupe (2016)
    Article
    Open Access
    The decision on the primary endpoint in a randomized clinical trial is of paramount importance and the combination of several endpoints might be a reasonable choice. Gómez and Lagakos (2013) have developed a method that ...
  • Selection of composite binary endpoints in clinical trials 

    Bofill Roig, Marta; Gómez Melis, Guadalupe (2017-10-12)
    Article
    Open Access
    The choice of a primary endpoint is an important issue when designing a clinical trial. It is common to use composite endpoints as a primary endpoint because it increases the number of observed events, captures more ...
  • Selection of the primary end point in an observational cohort study 

    Gómez Melis, Guadalupe; Plana Ripoll, Oleguer; Dafni, Urania (2016-04-12)
    Article
    Open Access
    Any study exploring specific research questions requires to test well-defined hypotheses that efficiently translate these questions into measurable quantities. To attribute differences in outcomes between two or more groups ...
  • Semi-competing risks methods accounting for interval-censoring 

    Porta Bleda, Núria; Calle Rosingana, M. Luz; Gómez Melis, Guadalupe (2009)
    Conference lecture
    Open Access